Browsing by Author "Steinmetz, Lars M."

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  • Nadal Ribelles, Mariona, 1984-; Solé, Carme; Xu, Zhenyu; Steinmetz, Lars M.; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Elsevier, 2014)
    Genomic analysis has revealed the existence of a large number of long noncoding RNAs (lncRNAs) with different functions in a variety of organisms, including yeast. Cells display dramatic changes of gene expression upon ...
  • Vonesch, Sibylle C.; Li, Shengdi; Szu-Tu, Chelsea; Henning, Bianca P.; Dobrev, Nikolay; Steinmetz, Lars M. (Oxford University Press, 2021)
    Through the increase in the capacity of sequencing machines massively parallel sequencing of thousands of samples in a single run is now possible. With the improved throughput and resulting drop in the price of sequencing, ...
  • Velten, Lars; Story, Benjamin A.; Hernández-Malmierca, Pablo; Raffel, Simon; Leonce, Daniel R.; Milbank, Jennifer; Paulsen, Malte; Demir, Aykut; Szu-Tu, Chelsea; Frömel, Robert; Lutz, Christoph; Novak, Daniel; Jann, Johann-Christoph; Pabst, Caroline; Boch, Tobias; Hofmann, Wolf-Karsten; Müller-Tidow, Carsten; Trumpp, Andreas; Haas, Simon; Steinmetz, Lars M. (Nature Research, 2021)
    Cancer stem cells drive disease progression and relapse in many types of cancer. Despite this, a thorough characterization of these cells remains elusive and with it the ability to eradicate cancer at its source. In acute ...
  • Carter, Jason A.; Strömich, Léonie; Peacey, Matthew; Chapin, Sarah R.; Velten, Lars; Steinmetz, Lars M.; Brors, Benedikt; Pinto, Sheena; Meyer, Hannah V. (Nature Research, 2022)
    The induction of central T cell tolerance in the thymus depends on the presentation of peripheral self-epitopes by medullary thymic epithelial cells (mTECs). This promiscuous gene expression (pGE) drives mTEC transcriptomic ...
  • Carter, Jason A.; Strömich, Léonie; Peacey, Matthew; Chapin, Sarah R.; Velten, Lars; Steinmetz, Lars M.; Brors, Benedikt; Pinto, Sheena; Meyer, Hannah V. (Nature Research, 2022)
    The induction of central T cell tolerance in the thymus depends on the presentation of peripheral self-epitopes by medullary thymic epithelial cells (mTECs). This promiscuous gene expression (pGE) drives mTEC transcriptomic ...

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