Browsing by Author "Stam, Ronald W."

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  • A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1
    Closa, Adrià; Reixachs-Solé, Marina; Fuentes-Fayos, Antonio C.; Hayer, Katharina E.; Melero, Juan L.; Adriaanse, Fabienne R.S.; Bos, Romy S.; Torres-Diz, Manuel; Hunger, Stephen P.; Roberts, Kathryn G.; Mullighan, Charles G.; Stam, Ronald W.; Thomas-Tikhonenko, Andrei; Castaño, Justo P.; Luque, Raul M.; Eyras Jiménez, Eduardo (Oxford University Press, 2022)
    A significant proportion of infant B-cell acute lymphoblastic leukemia (B-ALL) patients remains with a dismal prognosis due to yet undetermined mechanisms. We performed a comprehensive multicohort analysis of gene expression, ...
  • Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis
    Agraz-Doblas, Antonio; Bueno, Clara; Bashford-Rogers, Rachael; Roy, Anindita; Schneider, Pauline; Bardini, Michela; Ballerini, Paola; Cazzaniga, Gianni; Moreno, Thaidy; Revilla, Carlos; Gut, Marta; Valsecchi, Maria G.; Roberts, Irene; Pieters, Rob; De Lorenzo, Paola; Varela, Ignacio; Menéndez, Pablo; Stam, Ronald W. (Ferrata Storti Foundation, 2019)
    B-cell acute lymphoblastic leukemia is the commonest childhood cancer. In infants, B-cell acute lymphoblastic leukemia remains fatal, especially in patients with t(4;11), present in ~80% of cases. The pathogenesis of ...

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