Browsing by Author "Soler, María José"

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  • Palau González, Vanesa; Riera, Marta; Soler, María José (Oxford University Press, 2020)
  • Rodríguez, Eva; Latzke, Belén; Sierra Carpio, Milagros; Romera, Ana María; Siedel, Diego; Agraz, Irene; Soler, María José; García Carro, Clara; Draibe, Juliana; Prada, Francisco José de la; Villacorta, Javier; Buxeda, Anna; Sierra Ochoa, Adriana; Lozano, Inés; Durán, Xavier; Barrios Barrera, Clara; Pascual, Julio (Pascual Santos); Spanish Group for the Study of Glomerular Diseases (GLOSEN) (Oxford University Press, 2021)
    Background: The value of myeloperoxidase and proteinase 3 antibodies titers in the assessment of renal disease activity and flare prediction in patients with ANCA-associated-vasculitis (AAV) is not well-known. Methods: ...
  • Bermejo García, Sheila; García, Carles Oriol; Rodríguez García, Eva; Barrios Barrera, Clara; Otero, Sol; Mojal, Sergio; Pascual Santos, Julio; Soler, María José (Elsevier, 2018)
    BACKGROUND AND OBJECTIVES: Diabetic kidney disease is the leading cause of end-stage chronic kidney disease. The renin-angiotensin-aldosterone system (RAAS) blockade has been shown to slow the progression of diabetic kidney ...
  • Palau González, Vanesa; Nugraha, Bramasta; Benito, David; Pascual Santos, Julio; Emmert, Maximilian Y.; Hoerstrup, Simon P.; Riera, Marta; Soler, María José (MDPI, 2021)
    ADAM17 is a disintegrin and metalloproteinase capable of cleaving the ectodomains of a diverse variety of molecules including TNF-α, TGF-α, L-selectin, and ACE2. We have previously demonstrated that renal ADAM17 is upregulated ...
  • Roca-Ho, Heleia; Riera Oliva, Marta; Palau González, Vanesa; Pascual Santos, Julio; Soler, María José (MDPI, 2017)
    Renin angiotensin system (RAS) is known to play a key role in several diseases such as diabetes, and renal and cardiovascular pathologies. Its blockade has been demonstrated to delay chronic kidney disease progression and ...
  • Riera Oliva, Marta; Márquez, Eva; Clotet, Sergi; Gimeno Beltran, Javier; Roca-Ho, Heleia; Lloreta Trull, Josep, 1958-; Juanpere, Nuria; Batlle, Daniel; Pascual Santos, Julio; Soler, María José (Public Library of Science (PLoS), 2014)
    We studied the non-obese diabetic (NOD) mice model because it develops autoimmune diabetes that resembles human type 1 diabetes. In diabetic mice, urinary albumin excretion (UAE) was ten-fold increased at an “early stage” ...
  • Anguiano Gómez, Lidia; Riera Oliva, Marta; Pascual Santos, Julio; Soler, María José (MDPI, 2015)
    Diabetic kidney disease (DKD) remains the most common cause of chronic kidney disease and multiple therapeutic agents, primarily targeted at the renin-angiotensin system, have been assessed. Their only partial effectiveness ...
  • Bermejo García, Sheila; Soler, María José; Gimeno Beltran, Javier; Barrios Barrera, Clara; Rodríguez, Eva; Mojal, Sergio; Pascual Santos, Julio (Sociedad Española de Nefrologia, 2016)
    Antecedentes y objetivos: La afectación renal del diabético solo puede determinarse mediante biopsia renal, que presenta una elevada prevalencia de lesiones no diabéticas. Los objetivos del estudio fueron determinar la ...
  • Clotet, Sergi; Soler, María José; Rebull, Marta; Gimeno Beltran, Javier; Gurley, Susan Bailey; Pascual Santos, Julio; Riera Oliva, Marta (Lippincott Williams & Wilkins, 2016)
    BACKGROUND: Angiotensin-converting enzyme 2 (ACE2) deletion worsens kidney injury, and its amplification ameliorates diabetic nephropathy. Male sex increases the incidence, prevalence, and progression of chronic kidney ...
  • Rodriguez García, Eva; Arias Cabrales, Carlos Enrique; Bermejo García, Sheila; Sierra Ochoa, Adriana; Burballa Tàrrega, Carla, 1988-; Soler, María José; Barrios Barrera, Clara (Karger (S. Karger AG), 2018)
    BACKGROUND/AIMS: Recurrent acute kidney injury (AKI) is common among patients after a first hospitalized AKI. However, little is known about the prognosis of recurrent AKI episodes in chronic kidney disease (CKD) development, ...
  • Rodriguez García, Eva; Gimeno Beltran, Javier; Arias Cabrales, Carlos Enrique; Barrios Barrera, Clara; Redondo Pachón, María Dolores; Soler, María José; Crespo Barrio, Marta; Sierra Ochoa, Adriana; Riera Oliva, Marta; Pascual Santos, Julio (Karger (S. Karger AG), 2018)
    BACKGROUND AND AIMS: Complement system seems to play an important role in the pathogenesis of Acute Kidney Injury (AKI). The aim of this study was to investigate the role of complement system in the pathogenesis of human ...
  • Mora-Gutiérrez, José María; Rodríguez, José Antonio; Fernández-Seara, María A.; Orbe, Josune; Escalada, Francisco Javier; Soler, María José; Slon Roblero, María Fernanda; Riera Oliva, Marta; Páramo, José Antonio; García-Fernández, Nuria (Nature Research, 2020)
    Matrix metalloproteinases have been implicated in diabetic microvascular complications. However, little is known about the pathophysiological links between MMP-10 and the renin-angiotensin system (RAS) in diabetic kidney ...
  • Pombas, Beatriz; Sánchez Parrila, Juan; Radosevic, Aleksandar; Gimeno Beltran, Javier; Busto Barrera, Marcos; Barrios Barrera, Clara; Sans Atxer, Laia; Pascual Santos, Julio; Soler, María José (Karger (S. Karger AG), 2020)
    Introduction: Percutaneous renal biopsy (PRB) of native kidneys is an important tool for diagnosis and management of renal disease. In this study, we analyzed the success, safety, and risk complications of PRB in our center. ...
  • Bermejo García, Sheila; Pascual Santos, Julio; Soler, María José (Oxford University Press, 2020)
    Background: Diabetic patients with kidney disease have a high prevalence of non-diabetic renal disease (NDRD). Renal and patient survival regarding the diagnosis of diabetic nephropathy (DN) or NDRD have not been widely ...
  • Palau González, Vanesa; Pascual Santos, Julio; Soler, María José; Riera Oliva, Marta (American Physiological Society, 2019)
    It is known that the renin-angiotensin system plays a major role in the pathophysiology of cardiovascular disease and renal injury. Within the renin-angiotensin system, angiotensin-converting enzyme 2 (ACE2) cleaves ANG ...
  • Rodriguez García, Eva; Barrios Barrera, Clara; Soler, María José (Oxford University Press, 2017)
    Atypical hemolytic uremic syndrome (aHUS) is a life-threatening disorder for which prompt diagnosis and eculizumab treatment is indicated. The time for relapse and patients at risk for relapse after eculizumab discontinuation ...
  • Bermejo García, Sheila; Soler, María José; Pascual Santos, Julio (Oxford University Press, 2017)
    The prevalence of diabetic nephropathy (DN) among diabetic patients seems to be overestimated. Recent studies with renal biopsies show that the incidence of non-diabetic nephropathy (NDN) among diabetic patients is higher ...