Browsing by Author "Solé Vicente, Ricard, 1962-"

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  • A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology
    Carbonell Ballestero, Max, 1988-; Duran Nebreda, Salvador, 1987-; Montañez, Raúl; Solé Vicente, Ricard, 1962-; Macía, Javier; Rodríguez Caso, Carlos (Oxford University Press, 2014)
    Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses-the so-called transfer function-and how to tune them. However, a commonly ...
  • A cultural diffusion model for the rise and fall of programming languages
    Valverde, Sergi; Solé Vicente, Ricard, 1962- (Wayne State University Press, 2015)
    Our interaction with complex computing machines is mediated by programming languages (PLs), which constitute one of the major innovations in the evolution of technology. PLs allow flexible, scalable, and fast use of hardware ...
  • Accelerated tumor invasion under non-isotropic cell dispersal in glioblastomas
    Fort, Joaquim; Solé Vicente, Ricard, 1962- (IOP Science, 2013)
    Glioblastomas are highly diffuse, malignant tumors that have so far evaded clinical treatment. The strongly invasive behavior of cells in these tumors makes them very resistant to treatment, and for this reason both ...
  • Adaptive dynamics of unstable cancer populations: the canonical equation
    Solé Vicente, Ricard, 1962-; Aguadé Gorgorió, Guim, 1991- (Wiley, 2018)
    In most instances of tumour development, genetic instability plays a role in allowing cancer cell populations to respond to selection barriers, such as physical constraints or immune responses, and rapidly adapt to an ...
  • Ambiguity in language networks
    Solé Vicente, Ricard, 1962-; Seoane, Luís F., 1985- (De Gruyter, 2015)
    Human language defines the most complex outcomes of evolution. The emergence of such an elaborated form of communication allowed humans to create extremely structured societies and manage symbols at different levels ...
  • An oncospace for human cancers
    Aguadé Gorgorió, Guim, 1991-; Costa, José; Solé Vicente, Ricard, 1962- (Wiley, 2023)
    Human cancers comprise an heterogeneous array of diseases with different progression patterns and responses to therapy. However, they all develop within a host context that constrains their natural history. Since it occurs ...
  • Avoiding transcription factor competition at promoter level increases the chances of obtaining oscillations
    Munteanu, Andreea; Constante Pereira, Marco; Isalan, Mark; Solé Vicente, Ricard, 1962- (BioMed Central, 2010)
    Background: The ultimate goal of synthetic biology is the conception and construction of genetic circuits that are reliable with respect to their designed function (e.g. oscillators, switches). This task remains still to ...
  • Before the endless forms: embodied model of transition from single cells to aggregates to ecosystem engineering
    Solé Vicente, Ricard, 1962-; Valverde, Sergi (Public Library of Science (PLoS), 2013)
    The emergence of complex multicellular systems and their associated developmental programs is one of the major problems of evolutionary biology. The advantages of cooperation over individuality seem well known but it is ...
  • Biodiversity as a firewall to engineered microbiomes for restoration and conservation
    Maull, Victor; Solé Vicente, Ricard, 1962- (Royal Society, 2024)
    The possibility of abrupt transitions threatens to poise ecosystems into irreversibly degraded states. Synthetic biology has recently been proposed to prevent them from crossing tipping points. However, there is little ...
  • Bioremediation at a global scale: from the test tube to planet Earth
    de Lorenzo, Víctor; Marlière, Philippe; Solé Vicente, Ricard, 1962- (Wiley, 2016)
    Planet Earth's biosphere has evolved over billions of years as a balanced bio-geological system ultimately sustained by sunpower and the large-scale cycling of elements largely run by the global environmental microbiome. ...
  • Cellular heterogeneity results from indirect effects under metabolic tradeoffs
    Ollé-Vila, Aina; Solé Vicente, Ricard, 1962- (Royal Society, 2019)
    The emergence and maintenance of multicellularity requires the coexistence of diverse cellular populations displaying cooperative relationships. This enables long-term persistence of cellular consortia, particularly under ...
  • Chromatic transitions in the emergence of syntax networks
    Corominas Murtra, Bernat; Sànchez Fibla, Martí; Valverde, Sergi; Solé Vicente, Ricard, 1962- (Royal Society, 2018)
    The emergence of syntax during childhood is a remarkable example of how complex correlations unfold in nonlinear ways through development. In particular, rapid transitions seem to occur as children reach the age of two, ...
  • Computational implementation of a tunable multicellular memory circuit for engineered eukaryotic consortia
    Sardanyés i Cayuela, Josep; Bonforti, Adriano; Conde Pueyo, Núria, 1983-; Solé Vicente, Ricard, 1962-; Macía, Javier (Frontiers, 2015)
    Cells are complex machines capable of processing information by means of an entangled network of molecular interactions. A crucial component of these decision-making systems is the presence of memory and this is also a ...
  • Criticality in pareto optimal grammars?
    Seoane, Luís F., 1985-; Solé Vicente, Ricard, 1962- (MDPI, 2020)
    What are relevant levels of description when investigating human language? How are these levels connected to each other? Does one description yield smoothly into the next one such that different models lie naturally along ...
  • Design principles of stripe-forming motifs: the role of positive feedback
    Munteanu, Andreea; Cotterell, James; Solé Vicente, Ricard, 1962-; Sharpe, James (Nature Publishing Group, 2014)
    Interpreting a morphogen gradient into a single stripe of gene-expression is a fundamental unit of patterning in early embryogenesis. From both experimental data and computational studies the feed-forward motifs stand out ...
  • Do plants have the cognitive complexity for sentience?
    Solé Vicente, Ricard, 1962- (WellBeing International, 2023)
    Are plants sentient? Like other aspects of the cognitive potential of plants, this is a controversial issue, often driven by analogies and seldom supported on solid theoretical grounds. Sentience is understood in cognitive ...
  • Dynamics in a time-discrete food-chain model with strong pressure on preys
    Alsedà, Lluís; Vidiella Rocamora, Blai; Solé Vicente, Ricard, 1962-; Lázaro, J. Tomás; Sardanyés i Cayuela, Josep (Elsevier, 2020)
    Discrete-time dynamics, mainly arising in boreal and temperate ecosystems for species with non-overlapping generations, have been largely studied to understand the dynamical outcomes due to changes in relevant ecological ...
  • Ecological complexity and the biosphere: the next 30 years
    Solé Vicente, Ricard, 1962-; Levin, Simon (Royal Society, 2022)
    Global warming, habitat loss and overexploitation of limited resources are leading to alarming biodiversity declines. Ecosystems are complex adaptive systems that display multiple alternative states and can shift from one ...
  • Ecological firewalls for synthetic biology
    Vidiella Rocamora, Blai; Solé Vicente, Ricard, 1962- (Elsevier, 2022)
    It has been recently suggested that engineered microbial strains could be used to protect ecosystems from undesirable tipping points and biodiversity loss. A major concern in this context is the potential unintended ...
  • Emergent chemical behavior in variable-volume protocells
    Shirt-Ediss, Ben; Solé Vicente, Ricard, 1962-; Ruíz-Mirazo, Kepa (MPDI, 2015)
    Artificial protocellular compartments and lipid vesicles have been used as model systems to understand the origins and requirements for early cells, as well as to design encapsulated reactors for biotechnology. One prominent ...

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