Browsing by Author "Slama, Rémy"

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  • A systematic comparison of statistical methods to detect interactions in exposome-health associations
    Barrera Gómez, Jose; Agier, Lydiane; Portengen, Lützen; Chadeau-Hyam, Marc; Giorgis-Allemand, Lise; Siroux, Valérie; Robinson, Oliver; Vlaanderen, Jelle; González, Juan Ramón; Nieuwenhuijsen, Mark J.; Vineis, Paolo; Vrijheid, Martine; Vermeulen, Roel; Slama, Rémy; Basagaña Flores, Xavier (BioMed Central, 2017)
    There is growing interest in examining the simultaneous effects of multiple exposures and, more generally, the effects of mixtures of exposures, as part of the exposome concept (being defined as the totality of human ...
  • Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview
    Vrijheid, Martine; Basagaña Flores, Xavier; Gonzalez, Juan Ramon; Porcel, Joana; Bustamante Pineda, Mariona; Casas Sanahuja, Maribel; Dadvand, Payam; Fossati, Serena; Guxens Junyent, Mònica; Maitre, Léa; Nieuwenhuijsen, Mark J.; Ortiz, Rodney; Stratakis, Nikos; Sunyer Deu, Jordi; Slama, Rémy (Wolters Kluwer (LWW), 2021)
    Early life stages are vulnerable to environmental hazards and present important windows of opportunity for lifelong disease prevention. This makes early life a relevant starting point for exposome studies. The Advancing ...
  • Childhood exposure to non-persistent endocrine disrupting chemicals and multi-omic profiles: a panel study
    Fabbri, Lorenzo; Garlantézec, Ronan; Audouze, Karine; Bustamante Pineda, Mariona; Carracedo, Ángel; Chatzi, Leda; González, Juan Ramón; Gražulevičienė, Regina; Keun, Hector C.; Lau, Chung-Ho E.; Sabidó, Eduard; Siskos, Alexandros P.; Slama, Rémy; Thomsen, Cathrine; Wright, John; Yuan, Wen Lun; Casas, Maribel; Vrijheid, Martine; Maitre, Léa (Elsevier, 2023)
    Individuals are exposed to environmental pollutants with endocrine disrupting activity (endocrine disruptors, EDCs) and the early stages of life are particularly susceptible to these exposures. Previous studies have focused ...
  • Diet as a source of exposure to environmental contaminants for pregnant women and children from six european countries
    Papadopoulou, Eleni, 1985-; Haug, Line Småstuen; Sakhi, Amrit Kaur; Andrušaitytė, Sandra; Basagaña Flores, Xavier; Brantsaeter, Anne Lise; Casas Sanahuja, Maribel; Fernández-Barrés, Sílvia; Gražulevičienė, Regina; Knutsen, Helle Katrine; Maitre, Léa; Meltzer, Helle Margrete; McEachan, Rosemary R.C.; Roumeliotaki, Theano; Slama, Rémy; Vafeiadi, Marina, 1983-; Wright, John; Vrijheid, Martine; Thomsen, Cathrine; Chatzi, Leda (National Institute of Environmental Health Sciences, 2019)
    Background: Pregnant women and children are especially vulnerable to exposures to food contaminants, and a balanced diet during these periods is critical for optimal nutritional status. Objectives: Our objective was to ...
  • Early life multiple exposures and child cognitive function: A multi-centric birth cohort study in six European countries
    Julvez, Jordi; López Vicente, Mònica, 1988-; Warembourg, Charline; Maitre, Léa; Philippat, Claire; Gützkow, Kristine B.; Guxens Junyent, Mònica; Evandt, Jorunn; Andrušaitytė, Sandra; Burgaleta Díaz, Miguel, 1981-; Casas Sanahuja, Maribel; Chatzi, Leda; de Castro, Montserrat; Donaire González, David; Gražulevičienė, Regina; Hernandez-Ferrer, Carles, 1987-; Heude, Barbara; McEachan, Rosie; Mon-Williams, Mark; Nieuwenhuijsen, Mark J.; Robinson, Oliver; Sakhi, Amrit Kaur; Sebastián Gallés, Núria; Slama, Rémy; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Thomsen, Cathrine; Urquiza, José M.; Vafeiadi, Marina, 1983-; Basagaña Flores, Xavier; Vrijheid, Martine (Elsevier, 2021)
    Epidemiological studies mostly focus on single environmental exposures. This study aims to systematically assess associations between a wide range of prenatal and childhood environmental exposures and cognition. The study ...
  • Elemental Constituents of Particulate Matter and Newborn's Size in Eight European Cohorts.
    Pedersen, Marie; Basagaña Flores, Xavier; Cirach, Marta; Sunyer Deu, Jordi; Nieuwenhuijsen, Mark J.; Kogevinas, Manolis; Slama, Rémy (National Institute of Environmental Health Sciences (NIEHS), 2016)
    BACKGROUND: The health effects of suspended particulate matter (PM) may depend on its chemical composition. Associations between maternal exposure to chemical constituents of PM and newborn's size have been little examined. ...
  • Environmental burden of childhood disease in Europe
    Rojas Rueda, David, 1979-; Vrijheid, Martine; Robinson, Oliver; Gunn Marit, Aasvang; Gražulevičienė, Regina; Slama, Rémy; Nieuwenhuijsen, Mark J. (MDPI, 2019)
    Background: Environmental factors determine children's health. Quantifying the health impacts related to environmental hazards for children is essential to prioritize interventions to improve health in Europe. Objective: ...
  • Influence of the urban exposome on birth weight
    Nieuwenhuijsen, Mark J.; Basagaña Flores, Xavier; Urquiza, José M.; Maitre, Léa; de Castro, Montserrat; Valentín, Antònia; Donaire González, David; Dadvand, Payam; Vrijheid, Martine; Slama, Rémy (National Institute of Environmental Health Sciences, 2019)
    Background: The exposome is defined as the totality of environmental exposures from conception onwards. It calls for providing a holistic view of environmental exposures and their effects on human health by evaluating ...
  • Obesity is associated with shorter telomeres in 8 year-old children
    Clemente Batalha Pardal, Diana, 1990-; Maitre, Léa; Bustamante Pineda, Mariona; Chatzi, Leda; Roumeliotaki, Theano; Fossati, Serena; Gražulevičienė, Regina; Gützkow, Kristine B.; Lepeule, Johanna; Martens, Dries S.; McEachan, Rosemary R.C.; Meltzer, Helle Margrete; Petraviciene, Inga; Slama, Rémy; Tamayo-Uria, Ibon; Urquiza, José M.; Vafeiadi, Marina, 1983-; Wright, John; Nawrot, Tim S.; Vrijheid, Martine (Nature Research, 2019)
    Telomere length is considered a biomarker of biological aging. Shorter telomeres and obesity have both been associated with age-related diseases. To evaluate the association between various indices of obesity with leukocyte ...
  • Performance of approaches relying on multidimensional intermediary data to decipher causal relationships between the exposome and health: A simulation study under various causal structures
    Cadiou, Solène; Basagaña Flores, Xavier; González, Juan Ramón; Lepeule, Johanna; Vrijheid, Martine; Siroux, Valérie; Slama, Rémy (Elsevier, 2021)
    Challenges in the assessment of the health effects of the exposome, defined as encompassing all environmental exposures from the prenatal period onwards, include a possibly high rate of false positive signals. It might be ...
  • Prenatal and childhood traffic-related air pollution exposure and telomere length in european children: The HELIX Project
    Clemente Batalha Pardal, Diana, 1990-; Vrijheid, Martine; Martens, Dries S.; Bustamante Pineda, Mariona; Chatzi, Leda; Danileviciute, Asta; de Castro, Montserrat; Gražulevičienė, Regina; Gutzkow, Kristine B.; Lepeule, Johanna; Maitre, Léa; McEachan, Rosemary R.C.; Robinson, Oliver; Schwarze, Per E.; Tamayo-Uria, Ibon; Vafeiadi, Marina, 1983-; Wright, John; Slama, Rémy; Nieuwenhuijsen, Mark J.; Nawrot, Tim S. (National Institute of Environmental Health Sciences, 2019)
    Background: Telomere length is a molecular marker of biological aging. Objective: Here we investigated whether early-life exposure to residential air pollution was associated with leukocyte telomere length (LTL) at 8 y of ...
  • Unravelling sex-specific BPA toxicokinetics in children using a pediatric PBPK model
    Deepika, Deepika; Sharma, Raju Prasad; Schuhmacher, Marta; Sakhi, Amrit Kaur; Thomsen, Cathrine; Chatzi, Leda; Vafeiadi, Marina, 1983-; Quentin, Joane; Slama, Rémy; Gražulevičienė, Regina; Andrušaitytė, Sandra; Waiblinger, Dagmar; Wright, John; Yang, Tiffany C.; Urquiza, José M.; Vrijheid, Martine; Casas Sanahuja, Maribel; Domingo, José L.; Kumar, Vikas (Elsevier, 2022)
    Bisphenol A (BPA) is a widely known endocrine disruptor (ED) found in many children's products such as toys, feeding utensils, and teething rings. Recent epidemiology association studies have shown postnatal BPA exposure ...
  • Urban environment during early-life and blood pressure in young children
    Warembourg, Charline; Nieuwenhuijsen, Mark J.; Ballester, Ferran; de Castro, Montserrat; Chatzi, Leda; Esplugues, Ana; Heude, Barbara; Maitre, Léa; McEachan, Rosemary R.C.; Robinson, Oliver; Slama, Rémy; Sunyer Deu, Jordi; Urquiza, José M.; Wright, John; Basagaña Flores, Xavier; Vrijheid, Martine (Elsevier, 2021)
    Background: The urban environment is characterised by many exposures that may influence hypertension development from early life onwards, but there is no systematic evaluation of their impact on child blood pressure (BP). ...
  • Urinary metabolite quantitative trait loci in children and their interaction with dietary factors
    Calvo Serra, Beatriz; Maitre, Léa; Lau, Chung-Ho E.; Siskos, Alexandros P.; Gützkow, Kristine B.; Andrušaitytė, Sandra; Casas Sanahuja, Maribel; Cadiou, Solène; Chatzi, Leda; González, Juan Ramón; Gražulevičienė, Regina; McEachan, Rosemary R.C.; Slama, Rémy; Vafeiadi, Marina, 1983-; Wright, John; Coen, Muireann; Vrijheid, Martine; Keun, Hector C.; Escaramís, Geòrgia; Bustamante Pineda, Mariona (Oxford University Press, 2021)
    Human metabolism is influenced by genetic and environmental factors. Previous studies have identified over 23 loci associated with more than 26 urine metabolites levels in adults, which are known as urinary metabolite ...
  • Using methylome data to inform exposome-health association studies: An application to the identification of environmental drivers of child body mass index
    Cadiou, Solène; Bustamante Pineda, Mariona; Basagaña Flores, Xavier; González, Juan Ramón; Maitre, Léa; Nieuwenhuijsen, Mark J.; Vrijheid, Martine; Slama, Rémy (Elsevier, 2020)
    Background: The exposome is defined as encompassing all environmental exposures one undergoes from conception onwards. Challenges of the application of this concept to environmental-health association studies include a ...