Browsing by Author "Sharma, Priyanka"

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  • Hormone-control regions mediate steroid receptor-dependent genome organization
    Le Dily, François; Vidal, Enrique; Cuartero, Yasmina; Quilez Oliete, Javier; Nacht, A. Silvina; Vicent, Guillermo Pablo; Carbonell-Caballero, Jose; Sharma, Priyanka; Villanueva Cañas, José Luis, 1984-; Ferrari, Roberto; De Llobet, Lara Isabel; Verde, Gaetano; Wright, Roni H.G.; Beato, Miguel (Cold Spring Harbor Laboratory Press (CSHL Press), 2019)
    In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. Here we further ...
  • Hormone-induced repression of genes requires BRG1-mediated H1.2 deposition at target promoters
    Nacht, A. Silvina; Pohl, Andy, 1979-; Zaurín Quer, Roser; Soronellas, Daniel; Quilez Oliete, Javier; Sharma, Priyanka; Wright, Roni H.G.; Beato, Miguel; Vincent, Guillermo P. (EMBO Press, 2016)
    Eukaryotic gene regulation is associated with changes in chromatin compaction that modulate access to DNA regulatory sequences relevant for transcriptional activation or repression. Although much is known about the mechanism ...
  • Peptidyl arginine deiminase 2 (PADI2)-mediated arginine citrullination modulates transcription in cancer
    Beato, Miguel; Sharma, Priyanka (MDPI, 2020)
    Protein arginine deimination leading to the non-coded amino acid citrulline remains a key question in the field of post-translational modifications ever since its discovery by Rogers and Simmonds in 1958. Citrullination ...