Browsing by Author "Serrano, Lourdes"

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  • Bosch Presegué, Laia; Raurell Vila, Helena; Thackray, Joshua K.; González, Jessica V.; Casal, Carmen; Kane-Goldsmith, Noriko; Vizoso, Miguel; Brown, Jeremy P.; Gómez, Antonio; Ausió, Juan; Zimmermann, Timo; Esteller, Manel; Schotta, Gunnar; Singh, Prim B.; Serrano, Lourdes; Vaquero, Alejandro (Elsevier, 2017)
    HP1 is a structural component of heterochromatin. Mammalian HP1 isoforms HP1α, HP1β, and HP1γ play different roles in genome stability, but their precise role in heterochromatin structure is unclear. Analysis of Hp1α-/-, ...
  • Santos-Barriopedro, Irene; Bosch-Presegué, Laia; Marazuela-Duque, Anna; Torre, Carolina de la; Colomer Montañá, Carlota; Vázquez, Berta N.; Fuhrmann, Thomas; Martínez-Pastor, Bárbara; Lu, Wenfu; Braun, Thomas; Bober, Eva; Jenuwein, Thomas; Serrano, Lourdes; Esteller, Manel; Chen, Zhenbang; Barceló-Batllori, Silvia; Mostoslavsky, Raúl; Espinosa Blay, Lluís; Vaquero, Alejandro (Nature Publishing Group, 2018)
    Sirtuins are NAD+-dependent deacetylases that facilitate cellular stress response. They include SirT6, which protects genome stability and regulates metabolic homeostasis through gene silencing, and whose loss induces an ...