Browsing by Author "Serra Pascual, Selma A., 1981-"

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  • Bahamonde Santos, María Isabel, 1972-; Serra Pascual, Selma A., 1981-; Drechsel, Oliver; Rahman, Rubayte; Marcé-Grau, Anna; Prieto, Marta; Ossowski, Stephan; Macaya, Alfons; Fernández-Fernández, José Manuel, 1967- (Public Library of Science (PLoS), 2015)
    Mutations in the CACNA1A gene, encoding the pore-forming CaV2.1 (P/Q-type) channel α1A subunit, result in heterogeneous human neurological disorders, including familial and sporadic hemiplegic migraine along with episodic ...
  • Serra Pascual, Selma A., 1981- (Universitat Pompeu Fabra, 2011-07-04)
    Migraine is one of most disabling neurological disorders for which the genetic and molecular mechanisms are not fully resolved. This PhD thesis has focused on the functional characterization of two new missense mutations ...
  • Hung, Wei-Chien; Yang, Jessica R.; Yankaskas, Christopher L.; Wong, Bin Sheng; Wu, Pei-Hsun; Pardo Pastor, Carlos; Serra Pascual, Selma A., 1981-; Chiang, Meng-Jung; Gu, Zhizhan; Wirtz, Denis; Valverde, M. A. (Miguel Ángel), 1963-; Zhang, Jin; Konstantopoulos, Konstantinos (Elsevier, 2016)
    Cells adopt distinct signaling pathways to optimize cell locomotion in different physical microenvironments. However, the underlying mechanism that enables cells to sense and respond to physical confinement is unknown. ...
  • Serra Pascual, Selma A., 1981-; Gené, Gemma; Elorza Vidal, Xabier; Fernández-Fernández, José Manuel, 1967- (Wiley, 2018)
    Modulation of CaV 2.1 channel activity plays a key role in interneuronal communication and synaptic plasticity. SNAREs interact with a specific synprint site at the second intracellular loop (LII-III) of the CaV 2.1 ...
  • Fernandes, Jacqueline; Lorenzo, Ivan M.; Andrade, Yaniré N.; Garcia-Elias Heras, Anna; Serra Pascual, Selma A., 1981-; Fernández-Fernández, José Manuel, 1967-; Valverde, M. A. (Miguel Ángel), 1963- (Rockefeller University Press, 2008)
    Mechanical and osmotic sensitivity of the transient receptor potential vanilloid 4 (TRPV4) channel depends on phospholipase A(2) (PLA(2)) activation and the subsequent production of the arachidonic acid metabolites, ...
  • Rovira Clusellas, Meritxell; Delaspre, Fabien; Massumi, Mohammad; Serra Pascual, Selma A., 1981-; Valverde, M. A. (Miguel Ángel), 1963-; Lloreta Trull, Josep, 1958-; Dufresne, Marlène; Payré, Bruno; Konieczny, Stephen F.; Savatier, Pierre; Real, Francisco X.; Skoudy, Anouchka (Elsevier, 2008)
    Background & Aims: Acinar cells constitute 90% of the pancreas epithelium, are polarized, and secrete digestive enzymes. These cells play a crucial role in pancreatitis and pancreatic cancer. However, there are limited ...
  • Carreño, Oriel; Corominas, Roser; Serra Pascual, Selma A., 1981-; Sintas, Cèlia; Fernández Castillo, Noelia; Vila Pueyo, Marta; Toma, Claudio; Gené, Gemma; Pons, Roser; Llaneza, Miguel; Sobrido, María Jesús; Grinberg, Daniel; Valverde, M. A. (Miguel Ángel), 1963-; Fernández-Fernández, José Manuel, 1967-; Macaya, Alfons; Cormand, Bru (Wiley, 2013)
    Hemiplegic migraine (HM) is a rare and severe subtype of autosomal dominant migraine, characterized by a complex aura including some degree of motor weakness. Mutations in four genes (CACNA1A, ATP1A2, SCN1A and PRRT2) have ...
  • Berna Erro, Alejandro; Izquierdo Serra, Mercè; Sepúlveda, Romina V.; Rubio Moscardó, Fanny; Doñate-Macián, Pau; Serra Pascual, Selma A., 1981-; Carrillo García, Julia; Perálvarez Marín, Alex; González Nilo, Fernando; Fernández-Fernández, José Manuel, 1967-; Valverde, M. A. (Miguel Ángel), 1963- (Nature Publishing Group, 2017)
    TRPV4 cation channel activation by cytochrome P450-mediated derivatives of arachidonic acid (AA), epoxyeicosatrienoic acids (EETs), constitute a major mechanisms of endothelium-derived vasodilatation. Besides, TRPV4 ...