Browsing by Author "Segalés Dalmau, Jessica"

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  • Sreenivasan, Krishnamoorthy; Rodríguez de la Rosa, Alejandra; Kim, Johnny; Mesquita, Diana; Segalés Dalmau, Jessica; Gómez del Arco, Pablo; Espejo, Isabel; Ianni, Alessandro; Di Croce, Luciano; Relaix, Frederic; Redondo, Juan Miguel; Braun, Thomas; Serrano Sánchez, Antonio L.; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962- (Elsevier, 2021)
    Regeneration of skeletal muscle requires resident stem cells called satellite cells. Here, we report that the chromatin remodeler CHD4, a member of the nucleosome remodeling and deacetylase (NuRD) repressive complex, is ...
  • Segalés Dalmau, Jessica; Islam, Abul, 1978-; Kumar, Roshan; Liu, Qi-Cai; Sousa-Victor, Pedro; Dilworth, F. Jeffrey; Ballestar, Esteban; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962- (BioMed Central, 2016)
    Background: Extracellular stimuli induce gene expression responses through intracellular signaling mediators. The p38 signaling pathway is a paradigm of the mitogen-activated protein kinase (MAPK) family that, although ...
  • Hong, Xiaotong; Isern, Joan; Campanario, Silvia; Perdiguero, Eusebio, 1968-; Ramírez Pardo, Ignacio; Segalés Dalmau, Jessica; Hernansanz-Agustín, Pablo; Curtabbi, Andrea; Deryagin, Oleg; Pollán, Angela; González-Reyes, José A.; Villalba, José M.; Sandri, Marco; Serrano Sánchez, Antonio L.; Enríquez, José Antonio; Muñoz Cánoves, Pura, 1962- (Elsevier, 2022)
    Skeletal muscle regeneration depends on the correct expansion of resident quiescent stem cells (satellite cells), a process that becomes less efficient with aging. Here, we show that mitochondrial dynamics are essential ...
  • Segalés Dalmau, Jessica; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962- (Frontiers, 2016)
    Formation of skeletal muscle fibers (myogenesis) during development and after tissue injury in the adult constitutes an excellent paradigm to investigate the mechanisms whereby environmental cues control gene expression ...
  • Moiseeva, Victoria, 1992-; Cisneros, Andrés; Sica, Valentina; Deryagin, Oleg; Andrés, Eva; Segalés Dalmau, Jessica; Ortet Cortada, Laura; Lukesova, Vera; Serrano Sánchez, Antonio L.; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962- (Nature Research, 2023)
    Tissue regeneration requires coordination between resident stem cells and local niche cells1,2. Here we identify that senescent cells are integral components of the skeletal muscle regenerative niche that repress regeneration ...
  • Segalés Dalmau, Jessica; Perdiguero, Eusebio, 1968-; Serrano, Antonio L.; Sousa-Victor, Pedro; Ortet Cortada, Laura; Jardí, Mercè; Budanov, Andrei V.; García-Prat, Laura, 1987-; Sandri, Marco; Thomson, David M.; Karin, Michael; Hee Lee, Jun; Muñoz Cánoves, Pura, 1962- (Nature Research, 2020)
    A unique property of skeletal muscle is its ability to adapt its mass to changes in activity. Inactivity, as in disuse or aging, causes atrophy, the loss of muscle mass and strength, leading to physical incapacity and poor ...
  • Chang, Natasha C.; Sincennes, Marie-Claude; Chevalier, Fabien P.; Brun, Caroline E.; Lacaria, Melanie; Segalés Dalmau, Jessica; Muñoz Cánoves, Pura, 1962-; Ming, Hong; Rudnicki, Michael A. (Elsevier, 2018)
    Asymmetrically dividing muscle stem cells in skeletal muscle give rise to committed cells, where the myogenic determination factor Myf5 is transcriptionally activated by Pax7. This activation is dependent on Carm1, which ...

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