Browsing by Author "Sebastián Pérez, Rubén"

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  • Neguembor, Maria Victoria; Sebastián Pérez, Rubén; Aulicino, Francesco, 1987-; Gómez García, Pablo; Cosma, Maria Pia, 1970-; Lakadamyali, Melike (Oxford University Press, 2018)
    CRISPR/dCas9-based labeling has allowed direct visualization of genomic regions in living cells. However, poor labeling efficiency and signal-to-background ratio have limited its application to visualize genome organization ...
  • Sebastián Pérez, Rubén; Nakagawa, Shoma; Tu, Xiaochuan; Aranda Aragón, Sergio; Pesaresi, Martina; Gómez García, Pablo; Alcoverro-Bertran, Marc; Gómez Vázquez, José Luis; Carnevali, Davide; Borràs, Eva; Sabidó Aguadé, Eduard, 1981-; Martin, Laura; Nissim Rafinia, Malka; Meshorer, Eran; Neguembor, Maria Victoria; Di Croce, Luciano; Cosma, Maria Pia (eLife, 2023)
    Chromocenters are established after the 2-cell (2C) stage during mouse embryonic development, but the factors that mediate chromocenter formation remain largely unknown. To identify regulators of 2C heterochromatin ...
  • Pesaresi, Martina; Bonilla-Pons, Sergi A.; Sebastián Pérez, Rubén; Di Vicino, Umberto; Alcoverro-Bertran, Marc; Michael, Ralph; Cosma, Maria Pia (Science Direct, 2021)
    Cell therapy approaches hold great potential for treating retinopathies, which are currently incurable. This study addresses the problem of inadequate migration and integration of transplanted cells into the host retina. ...
  • Neguembor, Maria Victoria; Martin, Laura; Castells García, Àlvaro, 1991-; Gómez García, Pablo; Vicario, Chiara; Carnevali, Davide; Abed, Jumana AlHaj; Granados, Alba; Sebastián Pérez, Rubén; Sottile, Francesco, 1988-; Solon, Jérôme; Wu, Chao-Ting; Lakadamyali, Melike; Cosma, Maria Pia, 1970- (Elsevier, 2021)
    The chromatin fiber folds into loops, but the mechanisms controlling loop extrusion are still poorly understood. Using super-resolution microscopy, we visualize that loops in intact nuclei are formed by a scaffold of cohesin ...

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