Browsing by Author "Schimmang, Thomas"

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  • Domínguez Frutos, Elena; López Hernández, Iris; Vendrell, Víctor; Neves, Joana; Gallozzi, Micaela; Gutsche, Katja; Quintana, Laura; Sharpe, James; Knoepfler, Paul S.; Eisenman, Robert N.; Trumpp, Andreas; Giráldez, Fernando; Schimmang, Thomas (Society for Neuroscience, 2011)
    Myc family members play crucial roles in regulating cell proliferation, size, and differentiation during organogenesis. Both N-myc and c-myc are expressed throughout inner ear development. To address their function in the ...
  • Vendrell, Víctor; López Hernández, Iris; Durán Alonso, Beatriz; Feijoo Redondo, Ana; Abelló Sumpsi, Gina, 1980-; Gálvez García, Héctor, 1989-; Giráldez, Fernando; Lamonerie, Thomas; Schimmang, Thomas (Company of Biologists, 2015)
    Transcriptional regulatory networks are essential during the formation and differentiation of organs. The transcription factor N-myc is required for proper morphogenesis of the cochlea and to control correct patterning of ...
  • Vendrell, Víctor; Vázquez Echeverría, Citlali; López Hernández, Iris; Durán Alonso, Beatriz; Martinez, Salvador; Pujades Corbi, Cristina; Schimmang, Thomas (Elsevier, 2013)
    Fgf and Wnt signalling have been shown to be required for formation of the otic placode in vertebrates. Whereas several Fgfs including Fgf3, Fgf8 and Fgf10 have been shown to participate during early placode induction, Wnt ...
  • Duran Alonso, María Beatriz; López Hernández, Iris; Fuente, Miguel Angel de la; Garcia-Sancho, Javier; Giráldez, Fernando; Schimmang, Thomas (Public Library of Science (PLoS), 2018)
    Hearing loss is the most common sensorineural disorder, affecting over 5% of the population worldwide. Its most frequent cause is the loss of hair cells (HCs), the mechanosensory receptors of the cochlea. HCs transduce ...