Browsing by Author "Saura, Cristina"

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  • Clearance of ctDNA in triple-negative and HER2-positive breast cancer patients during neoadjuvant treatment is correlated with pathologic complete response
    Ciriaco, Nikaoly; Zamora, Esther; Escrivá-de-Romaní, Santiago; Miranda Gómez, Ignacio; Jiménez Flores, José; Saura, Cristina; Sloane, Hillary; Starus, Anna; Fredebohm, Johannes; Georgieva, Lucy; Speight, Graham; Jones, Frederick; Ramón y Cajal, Santiago; Espinosa-Bravo, Martín; Peg, Vicente (SAGE Publications, 2022)
    Background: Although the standard of care is to perform surgery of primary breast cancer (BC) after neoadjuvant chemotherapy (NAC), for certain patients achieving clinical complete response (cCR) and pathologic complete ...
  • Early-stage breast cancer detection in breast milk
    Saura, Cristina; Arribas, Joaquín; Sansó Martínez, Miriam, 1979- (American Association for Cancer Research (AACR), 2023)
    Breast cancer occurring during pregnancy (PrBC) and postpartum (PPBC) is usually diagnosed at more advanced stages compared with other breast cancer, worsening its prognosis. PPBC is particularly aggressive, with increased ...
  • GDF15 is an eribulin response biomarker also required for survival of DTP breast cancer cells
    Bellio, Chiara; Emperador, Marta; Castellano, Pol; Gris-Oliver, Albert; Canals, Francesc; Sánchez Pla, Alexandre; Zamora, Esther; Arribas, Joaquín; Saura, Cristina; Serra, Violeta; Tabernero Cartula, Josep; Littlefield, Bruce A.; Villanueva, Josep (MDPI, 2022)
    Drug tolerant persister (DTP) cells enter into a reversible slow-cycling state after drug treatment. We performed proteomic characterization of the breast cancer (BC) DTP cell secretome after eribulin treatment. We showed ...
  • Therapy-induced senescence enhances the efficacy of HER2-targeted antibody-drug conjugates in breast cancer
    Duro-Sánchez, Santiago; Nadal-Serrano, Mercedes; Lalinde-Gutiérrez, Marta; Arenas, Enrique J.; Bernadó Morales, Cristina; Morancho Armisen, Beatriz; Escorihuela, Marta; Pérez-Ramos, Sandra; Escrivá-de-Romaní, Santiago; Gandullo-Sánchez, Lucía; Pandiella, Atanasio; Esteve-Codina, Anna; Rodilla, Verónica; Dijcks,Fred A.; Dokter, Wim H.A.; Cortés, Javier; Saura, Cristina; Arribas, Joaquín (American Association for Cancer Research (AACR), 2022)
    Antibody-drug conjugates (ADC) are antineoplastic agents recently introduced into the antitumor arsenal. T-DM1, a trastuzumab-based ADC that relies on lysosomal processing to release the payload, is approved for HER2-positive ...

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