Browsing by Author "Sala Vila, Aleix"

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  • Milà Alomà, Marta; Salvadó, Gemma; Gispert López, Juan Domingo; Vilor Tejedor, Natàlia, 1988-; Grau-Rivera, Oriol; Sala Vila, Aleix; Sánchez Benavides, Gonzalo; Arenaza Urquijo, Eider M.; Crous-Bou, Marta; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Suárez-Calvet, Marc; Molinuevo, José Luis; ALFA Study (Wiley, 2020)
    Introduction: The biological pathways involved in the preclinical stage of the Alzheimer's continuum are not well understood. Methods: We used NeuroToolKit and Elecsys® immunoassays to measure cerebrospinal fluid (CSF) ...
  • Sánchez Benavides, Gonzalo; Suárez-Calvet, Marc; Milà Alomà, Marta; Arenaza Urquijo, Eider M.; Grau-Rivera, Oriol; Operto, Grégory; Domingo Gispert, Juan; Vilor Tejedor, Natàlia, 1988-; Sala Vila, Aleix; Crous-Bou, Marta; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Molinuevo, José Luis; ALFA Study (Elsevier, 2021)
    Neurofilament light chain (NfL) is an axonal protein that when measured in cerebrospinal fluid (CSF) serves as a biomarker of neurodegeneration. We aimed at investigating the association among CSF NfL, presence of Subjective ...
  • Piñol, S.; Sala Vila, Aleix; Guzman, C.; Marcos, S.; Joya, Xavier; Puig, Carme; Velasco, Manel; Velez, D.; Vall Combelles, Oriol; García Algar, Oscar (Springer Verlag, 2015)
    Arsenic is a highly toxic element that pollutes groundwater, being a major environmental problem worldwide, especially in the Bengal Basin. About 40% of patients in our outpatient clinics come from those countries, and ...
  • Grau-Rivera, Oriol; Navalpotro Gómez, Irene; Sánchez Benavides, Gonzalo; Suárez-Calvet, Marc; Milà Alomà, Marta; Arenaza Urquijo, Eider M.; Salvadó, Gemma; Sala Vila, Aleix; Shekari, Mahnaz; González de Echávarri, José Maria; Minguillón, Carolina; Niñerola-Baizán, Aida; Perissinotti, Andrés; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Gispert López, Juan Domingo; Molinuevo, José Luis; ALFA Study (BioMed Central, 2021)
    Background: Recognizing clinical manifestations heralding the development of Alzheimer's disease (AD)-related cognitive impairment could improve the identification of individuals at higher risk of AD who may benefit from ...
  • Harris, William S.; Sala Vila, Aleix; The Fatty Acids and Outcomes Research Consortium (FORCE) (Nature Research, 2021)
    The health effects of omega-3 fatty acids have been controversial. Here we report the results of a de novo pooled analysis conducted with data from 17 prospective cohort studies examining the associations between blood ...
  • Lázaro, Iolanda; Rueda, Ferran; Cediel, German; Ortega, Emilio; García-García, Cosme; Sala Vila, Aleix; Bayés-Genís, Antoni (Elsevier, 2020)
    Background: Dietary omega-3 eicosapentaenoic acid (EPA) has multiple cardioprotective properties. The proportion of EPA in serum phosphatidylcholine (PC) mirrors dietary EPA intake during previous weeks. Circulating EPA ...
  • Milà Alomà, Marta; Shekari, Mahnaz; Salvadó, Gemma; Gispert López, Juan Domingo; Arenaza Urquijo, Eider M.; Operto, Grégory; Falcón, Carles; Vilor Tejedor, Natàlia, 1988-; Grau-Rivera, Oriol; Sala Vila, Aleix; Sánchez Benavides, Gonzalo; González de Echávarri, José Maria; Minguillón, Carolina; Suárez-Calvet, Marc; Molinuevo, José Luis; ALFA Study (BioMed Central, 2021)
    Background: Understanding the changes that occur in the transitional stage between absent and overt amyloid-β (Aβ) pathology within the Alzheimer's continuum is crucial to develop therapeutic and preventive strategies. The ...
  • Sala Vila, Aleix; Arenaza Urquijo, Eider M.; Sánchez Benavides, Gonzalo; Suárez-Calvet, Marc; Milà Alomà, Marta; Grau-Rivera, Oriol; González de Echávarri, José Maria; Crous-Bou, Marta; Minguillón, Carolina; Fauria, Karine; Operto, Grégory; Falcón, Carles; Salvadó, Gemma; Cacciaglia, Raffaele; Ingala, Silvia; Barkhof, Frederik; Schröder, Helmut, 1958-; Scarmeas, Nikolaos; Gispert López, Juan Domingo; Molinuevo, José Luis; ALFA Study (American Society for Nutrition, 2021)
    Background: The number of APOE-ε4 alleles is a major nonmodifiable risk factor for sporadic Alzheimer disease (AD). There is increasing evidence on the benefits of dietary DHA (22:6n-3) before the onset of AD symptoms, ...
  • Sala Vila, Aleix; Muñoz, Miguel Ángel; Fitó Colomer, Montserrat; Ros, Emilio; PREDIMED investigators (American Heart Association- Wiley, 2016)
    BACKGROUND: Epidemiological evidence suggests a cardioprotective role of α-linolenic acid (ALA), a plant-derived ω-3 fatty acid. It is unclear whether ALA is beneficial in a background of high marine ω-3 fatty acids ...
  • Amor, Antonio J.; Gómez-Guerrero, Carmen; Ortega, Emilio; Sala Vila, Aleix; Lázaro, Iolanda (MDPI, 2020)
    Oxidative stress contributes not only to the pathogenesis of type 2 diabetes (T2D) but also to diabetic vascular complications. It follows that antioxidants might contribute to limiting the diabetes burden. In this review ...
  • Muralidharan, Jananee; Papandreou, Christopher; Sala Vila, Aleix; Rosique-Esteban, Nuria; Fitó Colomer, Montserrat; Estruch, Ramón; Martínez-González, Miguel A.; Corella, Dolores; Ros, Emilio; Razquin, Cristina; Castañer, Olga; Salas-Salvadó, Jordi; Bulló, Mònica (MDPI, 2019)
    There is limited evidence from epidemiological studies for the inflammatory or anti-inflammatory properties of fatty acids in blood cell membranes. Therefore, this study examined associations between baseline (n = 282) and ...
  • Chrysafi, Pavlina; Perakakis,Nikolaos; Farr, Olivia M.; Stefanakis, Konstantinos; Peradze, Natia; Sala Vila, Aleix; Mantzoros, Christos S. (Nature Research, 2020)
    Based on studies in mice, leptin was expected to decrease body weight in obese individuals. However, the majority of the obese are hyperleptinemic and do not respond to leptin treatment, suggesting the presence of leptin ...
  • Valls Pedret, Cinta; Sala Vila, Aleix; Serra-Mir, Mercè; Corella, Dolores; Torre Fornell, Rafael de la; Martínez-González, Miguel A.; Martínez Lapiscina, Elena H.; Fitó Colomer, Montserrat; Pérez Heras, Ana; Salas-Salvadó, Jordi; Estruch, Ramón; Ros, Emilio (American Medical Association, 2015)
    IMPORTANCE: Oxidative stress and vascular impairment are believed to partly mediate age-related cognitive decline, a strong risk factor for development of dementia. Epidemiologic studies suggest that a Mediterranean diet, ...
  • Suárez-Calvet, Marc; Milà Alomà, Marta; Gispert López, Juan Domingo; Salvadó, Gemma; Minguillón, Carolina; Shekari, Mahnaz; Grau-Rivera, Oriol; Arenaza Urquijo, Eider M.; Sala Vila, Aleix; González de Echávarri, José Maria; Molinuevo, José Luis; ALFA Study (Wiley, 2020)
    In Alzheimer's disease (AD), tau phosphorylation in the brain and its subsequent release into cerebrospinal fluid (CSF) and blood is a dynamic process that changes during disease evolution. The main aim of our study was ...
  • Bargallo, Nuria; Gilabert, Rosa; Romero-Mamani, Edwin-Saúl; Cofán, Montserrat; Calder, Philip C.; Fitó Colomer, Montserrat; Corella, Dolores; Salas-Salvadó, Jordi; Ruiz-Canela, Miguel; Estruch, Ramón; Ros, Emilio; Sala Vila, Aleix (MDPI, 2017)
    Supplemental marine omega-3 eicosapentaenoic acid (EPA) has an anti-atherosclerotic effect. Clinical research on EPA supplied by the regular diet and atherosclerosis is scarce. In the framework of the PREvención con DIeta ...
  • García-Layana, Alfredo; Gianfranco, Ciufo; Toledo, Estefania; Martínez-González, Miguel A.; Corella, Dolores; Fitó Colomer, Montserrat; Estruch, Ramón; Gómez-Gracia, Enrique; Fiol, Miquel; Lapetra, José; Serra-Majem, Luis; Pinto, Xavier; Portillo, María P.; Sorlí, José Vicente; Bulló, Mònica; Vinyoles, Ernest; Sala Vila, Aleix; Ros, Emilio; Salas-Salvadó, Jordi; Arós, Fernando (MDPI, 2017)
    BACKGROUND: Cataract is a leading cause of vision impairment worldwide, and surgery is the only available treatment. The process that initiates lens opacification is dependent on the oxidative stress experienced by the ...
  • Díaz-Rizzolo, Diana A.; Serra, A.; Colungo, Cristina; Sala Vila, Aleix; Sisó-Almirall, Antoni; Gomis, Ramon (Elsevier, 2021)
    Background: Fish could play a role in preventing type 2 diabetes (T2D) but there has been little specification about the type of fish and the preventive mechanism involved in its health claim. The sardine is a source of ...