Browsing by Author "Sabidó Aguadé, Eduard, 1981-"

Sort by: Order: Results:

  • Roewenstrunk, Julia Maria, 1981-; Di Vona, Chiara, 1981-; Chen, Jie; Borràs, Eva; Dong, Chao; Arató, Krisztina, 1981-; Sabidó Aguadé, Eduard, 1981-; Huen, Michael S. Y.; Luna Gargantilla, Susana de la (Nature Research, 2019)
    Dysregulation of the DYRK1A protein kinase has been associated with human disease. On the one hand, its overexpression in trisomy 21 has been linked to certain pathological traits of Down syndrome, while on the other, ...
  • Sabidó Aguadé, Eduard, 1981-; Tarragó, Teresa; Niessen, Sherry; Cravatt, Benjamin F.; Giralt, Ernest (Wiley-VCH Verlag, 2009)
    Postproline proteases constitute a subset of serine proteases involved in the regulation of many signaling events and are emerging as promising therapeutic targets for prevalent diseases, such as diabetes and cancer. ...
  • Aranda Aragón, Sergio; Alcaine Colet, Anna; Blanco, Enrique; Borràs, Eva; Caillot, Claire; Sabidó Aguadé, Eduard, 1981-; Di Croce, Luciano (American Association for the Advancement of Science (AAAS), 2019)
    Profiling the chromatin-bound proteome (chromatome) in a simple, direct, and reliable manner might be key to uncovering the role of yet uncharacterized chromatin factors in physiology and disease. Here, we have designed ...
  • Liñeiro, Eva; Chiva, Cristina; Cantoral, Jesús M.; Sabidó Aguadé, Eduard, 1981-; Fernández-Acero, Francisco Javier (Elsevier, 2016)
    Phosphorylation is one of the main post-translational modification (PTM) involved in signaling network in the ascomycete Botrytis cinerea, one of the most relevant phytopathogenic fungus. The data presented in this article ...
  • Borràs, Eva; Sabidó Aguadé, Eduard, 1981- (American Chemical Society (ACS), 2018)
    Data-independent acquisition methods that acquire fragment ions from virtually any peptide in a sample have expanded the benefits of low-throughput targeted proteomics to proteome-wide analyses. While these methods have ...
  • Ortega Crespo, Mireia, 1988- (Universitat Pompeu Fabra, 2018-01-23)
    Down syndrome (DS) is the most frequent genetic cause of intellectual disability. It is a multifaceted condition characterized by impairments in cognition, communication, behavior and/or motor skills resulting from abnormal ...
  • Espadas, Guadalupe; Borràs, Eva; Chiva, Cristina; Sabidó Aguadé, Eduard, 1981- (Wiley, 2017)
    One of the major additions in MS technology has been the irruption of the Orbitrap mass analyzer, which has boosted the proteomics analyses of biological complex samples since its introduction. Here, we took advantage of ...
  • Sebé-Pedrós, Arnau; Peña Paz, Marcia I.; Capella Gutiérrez, Salvador Jesús, 1985-; Antó Subirats, Meritxell; Gabaldón Estevan, Juan Antonio, 1973-; Ruiz Trillo, Iñaki; Sabidó Aguadé, Eduard, 1981- (Elsevier, 2016)
    Cell-specific regulation of protein levels and activity is essential for the distribution of functions among multiple cell types in animals. The finding that many genes involved in these regulatory processes have a premetazoan ...
  • Maitre, Léa; de Bont, Jeroen; Casas Sanahuja, Maribel; Robinson, Oliver; Basagaña Flores, Xavier; Borràs, Eva; Bustamante Pineda, Mariona; de Castro, Montserrat; Donaire González, David; Estivill, Xavier, 1955-; Fossati, Serena; González, Juan R.; Hernández-Ferrer, Carles; Júlvez Calvo, Jordi; Manzano Salgado, Cyntia Beatriz, 1987-; Sabidó Aguadé, Eduard, 1981-; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; van Gent, Diana; Vives Usano, Marta, 1990-; Warembourg, Charline; Nieuwenhuijsen, M.; Vrijheid, Martine (BMJ Publishing Group, 2018)
    PURPOSE: Essential to exposome research is the collection of data on many environmental exposures from different domains in the same subjects. The aim of the Human Early Life Exposome (HELIX) study was to measure and ...
  • Vrijheid, Martine; Robinson, Oliver; Basagaña Flores, Xavier; Bustamante Pineda, Mariona; Casas, Maribel; Estivill, Xavier, 1955-; van Gent, Diana; González Ruiz, Juan Ramón; Júlvez Calvo, Jordi; Kogevinas, Manolis; Sabidó Aguadé, Eduard, 1981-; Sunyer Deu, Jordi; Nieuwenhuijsen, Mark J. (National Institute of Environmental Health Sciences (NIEHS), 2014)
    Background: Developmental periods in early life may be particularly vulnerable to impacts of environmental exposures. Human research on this topic has generally focused on single exposure–health effect relationships. The ...
  • Chiva, Cristina; Pastor, Olga; Trilla Fuertes, Lucía; Gámez Pozo, Angelo; Fresno Vara, Juan Ángel; Sabidó Aguadé, Eduard, 1981- (American Chemical Society (ACS), 2019)
    Targeted proteomics has become the method of choice for biomarker validation in human biopsies due to its high sensitivity, reproducibility, accuracy, and precision. However, for targeted proteomics to be transferred to ...
  • Campos, Alex; Díaz, Ramón; Martínez Bartolomé, Salvador; Sierra, Jose; Gallardo, Oscar; Sabidó Aguadé, Eduard, 1981-; López Lucendo, María; Casal, José Ignacio; Pasquarello, Carla; Scherl, Alexander; Chiva, Cristina; Borrás, Eva; Odena, Antonia; Elortza, Félix; Azkargorta, Mikel; Ibarrola, Nieves; Canals, Francesc; Albar, Juan P.; Oliveira, Eliandre (Elsevier, 2015)
    Proteomic technologies based on mass spectrometry (MS) have greatly evolved in the past years, and nowadays it is possible to routinely identify thousands of peptides from complex biological samples in a single LC-MS/MS ...
  • Casas, Caty; Isús Díaz, Laura, 1989-; Herrando Grabulosa, Mireia; Mancuso, Francesco M.; Borrás, Eva; Sabidó Aguadé, Eduard, 1981-; Forés, Joaquim; Aloy, Patrick, 1972- (Nature Publishing Group, 2015)
    Neurodegenerative processes are preceded by neuronal dysfunction and synaptic disconnection. Disconnection between spinal motoneuron (MN) soma and synaptic target leads either to a retrograde degenerative process or to a ...
  • Ruiz Orera, Jorge, 1988-; Hernández Rodríguez, Jéssica, 1983-; Chiva, Cristina; Sabidó Aguadé, Eduard, 1981-; Kondova, Ivanela; Bontrop, Ronald E.; Marquès i Bonet, Tomàs, 1975-; Albà Soler, Mar (Public Library of Science, 2015)
    The birth of new genes is an important motor of evolutionary innovation. Whereas many new genes arise by gene duplication, others originate at genomic regions that did not contain any genes or gene copies. Some of these ...
  • Chiva, Cristina; Sabidó Aguadé, Eduard, 1981- (American Chemical Society (ACS), 2017)
    Targeted proteomics methods in their different flavors rely on the use of a few peptides as proxies for protein quantitation, which need to be specified either prior to or after data acquisition. However, in contrast with ...
  • Gámez Pozo, Angelo; Trilla Fuertes, Lucía; Prado Vázquez, Guillermo; Chiva, Cristina; López Vacas, Rocío; Nanni, Paolo; Berges Soria, Julia; Grossmann, Jonas; Díaz Almirón, Mariana; Ciruelos, E.; Sabidó Aguadé, Eduard, 1981-; Espinosa Arranz, Enrique; Fresno Vara, Juan Ángel (Public Library of Science (PLoS), 2017)
    BACKGROUND: Triple-negative breast cancer (TNBC) accounts for 15-20% of all breast cancers and usually requires the administration of adjuvant chemotherapy after surgery but even with this treatment many patients still ...
  • Borrás, Eva; Cantó, Ester; Choi, Meena; Villar, Luisa Maria; Álvarez Cermeño, Jose Carlos; Chiva, Cristina; Montalbán Gairín, Xavier; Vitek, Olga; Comabella López, Manuel; Sabidó Aguadé, Eduard, 1981- (American Society for Biochemistry and Molecular Biology (ASBMB), 2016)
    Multiple sclerosis is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system. In most patients, the disease initiates with an episode of neurological disturbance referred to as clinically ...
  • Rojas Laimito, Katerin; Trilla Fuertes, Lucía; Gámez Pozo, Angelo; Chiva, Cristina; Sepúlveda, Juan M.; Manso, Luis; Prado Vázquez, Guillermo; Zapater-Moros, Andrea; López Vacas, Rocío; Ferrer-Gómez, María; Mendiola, César; Espinosa Arranz, Enrique; Sabidó Aguadé, Eduard, 1981-; Ciruelos, Eva; Fresno Vara, Juan Ángel (Cancer Intelligence, 2019)
    Background: Breast cancer (BC) is the most frequent tumour in women. Triple negative tumours (TNBC)–which are associated with minor survival rates—lack markers predictive of response to anticancer drugs. Triple negative ...
  • Imperlini, Esther; Gnecchi, Massimiliano; Rognoni, Paola; Sabidó Aguadé, Eduard, 1981-; Ciuffreda, Maria Chiara; Palladini, Giovanni; Espadas, Guadalupe; Mancuso, Francesco M.; Bozzola, Margherita; Malpasso, Giuseppe; Valentini, Veronica; Palladini, Giuseppina; Orrù, Stefania; Ferraro, Giovanni; Milani, Paolo; Perlini, Stefano; Salvatore, Francesco; Merlini, Giampaolo; Lavatelli, Francesca (Nature Publishing Group, 2017)
    AL amyloidosis is characterized by widespread deposition of immunoglobulin light chains (LCs) as amyloid fibrils. Cardiac involvement is frequent and leads to life-threatening cardiomyopathy. Besides the tissue alteration ...
  • Lluch-Senar, Maria 1982-; Mancuso, Francesco M.; Climente González, Héctor; Peña Paz, Marcia I.; Sabidó Aguadé, Eduard, 1981-; Serrano Pubull, Luis, 1982- (Wiley-VCH Verlag, 2016)
    A common problem encountered when performing large-scale MS proteome analysis is the loss of information due to the high percentage of unassigned spectra. To determine the causes behind this loss we have analyzed the ...