Muiño, Elena; Rodríguez-Campello, Ana; Romeral, Gemma; Roquer, Jaume; Fernández-Cadenas, Israel
(Nature Research, 2021)
CADASIL is a small vessel disease caused by mutations in NOTCH3 that lead to an odd number of cysteines in the EGF-like repeat domain, causing protein misfolding and aggregation. The main symptoms are migraine, psychiatric ...