Browsing by Author "Rodrigo Melero, Natalia"

Sort by: Order: Results:

  • Antibody conversion rates to SARS-CoV-2 in saliva from children attending summer schools in Barcelona, Spain
    Dobaño, Carlota; Rodrigo Melero, Natalia; Carolis, Carlo; Jordan, Iolanda (BioMed Central, 2021)
    Background: Surveillance tools to estimate viral transmission dynamics in young populations are essential to guide recommendations for school opening and management during viral epidemics. Ideally, sensitive techniques are ...
  • Determinants of early antibody responses to COVID-19 mRNA vaccines in a cohort of exposed and naïve healthcare workers
    Moncunill, Gemma; Aguilar, Ruth; Ribes, Marta; Ortega, Natalia; Rubio, Rocío; Molina, María José; Vidal, Marta; Barrios, Diana; Mitchell, Robert A.; Jiménez, Alfons; Castellana, Cristina; Rodó, Pau; Méndez, Susana; Llupià, Anna; Puyol, Laura; Rodrigo Melero, Natalia; Carolis, Carlo; Mayor, Alfredo; Izquierdo, Luis; Trilla, Antoni; Vilella, Anna; García-Basteiro, Alberto L.; Dobaño, Carlota (Elsevier, 2022)
    Background: Two doses of mRNA vaccination have shown >94% efficacy at preventing COVID-19 mostly in naïve adults, but it is not clear if the second dose is needed to maximize effectiveness in those previously exposed to ...
  • Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes
    Vicencio, Jeremy, 1990-; Sánchez-Bolaños, Carlos; Moreno-Sánchez, Ismael; Brena, David; Vejnar, Charles E.; Kukhtar, Dmytro; Ruiz-López, Miguel; Cots-Ponjoan, Mariona; Rubio, Alejandro; Rodrigo Melero, Natalia; Crespo-Cuadrado, Jesús; Carolis, Carlo; Pérez-Pulido, Antonio J.; Giráldez, Antonio; Kleinstiver, Benjamin P.; Cerón Madrigal, Julián; Moreno Mateos, Miguel Ángel (Nature Research, 2022)
    The requirement for Cas nucleases to recognize a specific PAM is a major restriction for genome editing. SpCas9 variants SpG and SpRY, recognizing NGN and NRN PAMs, respectively, have contributed to increase the number of ...
  • Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile
    Rubio, Rocío; Aguilar, Ruth; Bustamante Pineda, Mariona; Muñoz, Erica; Vázquez-Santiago, Miquel; Santano, Rebeca; Vidal, Marta; Rodrigo Melero, Natalia; Parras, Daniel; Serra, Pau; Santamaria, Pere; Carolis, Carlo; Izquierdo, Luis; Gómez-Roig, María Dolores; Dobaño, Carlota; Moncunill, Gemma; Mazarico, Edurne (Frontiers, 2022)
    SARS-CoV-2 infected pregnant women are at increased risk of severe COVID-19 than non-pregnant women and have a higher risk of adverse pregnancy outcomes like intrauterine/fetal distress and preterm birth. However, little ...
  • Multiplex antibody analysis of IgM, IgA and IgG to SARS-CoV-2 in saliva and serum from infected children and their close contacts
    Dobaño, Carlota; Alonso, Selena; Vidal, Marta; Jiménez, Alfons; Rubio, Rocío; Santano, Rebeca; Barrios, Diana; Puyol, Laura; Baró, Bàrbara; Millat-Martínez, Pere; Ajanovic, Sara; Balanza, Núria; Arias, Sara; Rodrigo Melero, Natalia; Carolis, Carlo; Bassat, Quique; Izquierdo, Luis; Aguilar, Ruth; Moncunill, Gemma (Frontiers, 2022)
    COVID-19 affects children to a lesser extent than adults but they can still get infected and transmit SARS-CoV-2 to their contacts. Field deployable non-invasive sensitive diagnostic techniques are needed to evaluate the ...
  • Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19
    Dobaño, Carlota; Ramírez-Morros, Anna; Alonso, Selena; Vidal Alaball, Josep; Ruiz-Olalla, Gemma; Vidal, Marta; Rubio, Rocío; Cascant, Emma; Parras, Daniel; Rodrigo Melero, Natalia; Serra, Pau; Carolis, Carlo; Santamaria, Pere; Forcada, Anna; Mendioroz Peña, Jacobo; Aguilar, Ruth; Moncunill, Gemma; Ruiz-Comellas, Anna (BioMed Central, 2021)
    We assessed the duration and baseline determinants of antibody responses to SARS-CoV-2 spike antigens and the occurrence of reinfections in a prospective cohort of 173 Spanish primary health care worker patients followed ...
  • SARS-CoV-2 sculpts the immune system to induce sustained virus-specific naïve-like and memory B-cell responses
    Campos Mata, Leire de, 1991-; Tejedor Vaquero, Sonia, 1988-; Tachó-Piñot, Roser; Piñero González, Janet, 1977-; Grasset, Emilie K.; Arrieta Aldea, Itziar; Rodrigo Melero, Natalia; Carolis, Carlo; Horcajada Gallego, Juan Pablo; Cerutti, Andrea, 1965-; Villar García, Judit; Magri, Giuliana, 1978- (Wiley Open Access, 2021)
    Objectives: SARS-CoV-2 infection induces virus-reactive memory B cells expressing unmutated antibodies, which hints at their emergence from naïve B cells. Yet, the dynamics of virus-specific naïve B cells and their impact ...
  • Seroprevalence and socioeconomic impact of the first SARS-CoV-2 infection wave in a small town in Navarre, Spain
    Ribes, Marta; Montañà, Júlia; Vidal, Marta; Aguilar, Ruth; Nicolás, Patricia; Alfonso, Uxue; Rodrigo Melero, Natalia; Carolis, Carlo; Dobaño, Carlota; Moncunill, Gemma; Chaccour, Carlos (Nature Research, 2023)
    The characterization of the antibody response to SARS-CoV-2 and its determinants are key for the understanding of COVID-19. The identification of vulnerable populations to the infection and to its socioeconomic impact is ...
  • Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses
    Ortega, Natalia; Ribes, Marta; Vidal, Marta; Rubio, Rocío; Aguilar, Ruth; Williams, Sarah; Barrios, Diana; Alonso, Selena; Mitchell, Robert A.; Jairoce, Chenjerai; Cruz, Angeline; Jimenez, Alfons; Santano, Rebeca; Méndez, Susana; Lamoglia, Montserrat; Rosell, Neus; Llupià, Anna; Puyol, Laura; Chi, Jordi; Rodrigo Melero, Natalia; Mayor, Alfredo; Vilella, Anna; Trilla, Antoni; Carolis, Carlo; Izquierdo, Luis; García-Basteiro, Alberto L.; Moncunill, Gemma; Dobaño, Carlota (Nature Research, 2021)
    Unraveling the long-term kinetics of antibodies to SARS-CoV-2 and the individual characteristics influencing it, including the impact of pre-existing antibodies to human coronaviruses causing common cold (HCoVs), is essential ...
  • Sustained seropositivity up to 20.5 months after COVID-19
    Dobaño, Carlota; Ramírez-Morros, Anna; Alonso, Selena; Rubio, Rocío; Ruiz-Olalla, Gemma; Vidal Alaball, Josep; Macià, Dídac; Miró Catalina, Queralt; Vidal, Marta; Fuster Casanovas, Aina; Prados de la Torre, Esther; Barrios, Diana; Jiménez, Alfons; Zanoncello, Jasmina; Rodrigo Melero, Natalia; Carolis, Carlo; Izquierdo, Luis; Aguilar, Ruth; Moncunill, Gemma; Ruiz-Comellas, Anna (BioMed Central, 2022)
    This study evaluated the persistence of IgM, IgA, and IgG to SARS-CoV-2 spike and nucleocapsid antigens up to 616 days since the onset of symptoms in a longitudinal cohort of 247 primary health care workers from Barcelona, ...
  • The mRNA-1273 vaccine induces cross-variant antibody responses to SARS-CoV-2 with distinct profiles in individuals with or without pre-existing immunity
    Tejedor Vaquero, Sonia, 1988-; Campos Mata, Leire de, 1991-; Ramada Rodilla, José María, 1961-; Díaz, Pilar; Navarro-Barriuso, Juan; Ribas-Llauradó, Clara; Rodrigo Melero, Natalia; Carolis, Carlo; Cerutti, Andrea, 1965-; Gimeno Martínez, Ramón; Magri, Giuliana, 1978- (Frontiers Media, 2021)
    mRNA-based vaccines effectively induce protective neutralizing antibodies against SARS-CoV-2, the etiological agent of COVID-19. Yet, the kinetics and compositional patterns of vaccine-induced antibody responses to the ...