Browsing by Author "Ralston, Stuart H."

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Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density

Alonso, Nerea; Garcia Giralt, Natàlia; Lucas, Gavin, 1977-; Elosua Llanos, Roberto; Ralston, Stuart H. (BMJ Publishing Group, 2018)

OBJECTIVES: To identify genetic determinants of susceptibility to clinical vertebral fractures, which is an important complication of osteoporosis. METHODS: Here we conduct a genome-wide association study in 1553 postmenopausal ...
Randomised trial of genetic testing and targeted intervention to prevent the development and progression of Paget's disease of bone

Phillips, Jonathan; Blanch-Rubió, Josep; Ralston, Stuart H. (BMJ Publishing Group, 2024)

Introduction: Paget's disease of bone (PDB) frequently presents at an advanced stage with irreversible skeletal damage. Clinical outcomes might be improved by earlier diagnosis and prophylactic treatment. Methods: We ...
Zoledronate in the prevention of Paget’s (ZiPP): protocol for a randomised trial of genetic testing and targeted zoledronic acid therapy to prevent SQSTM1-mediated Paget’s disease of bone

Cronin, Owen; Blanch-Rubió, Josep; Ralston, Stuart H. (BMJ Publishing Group, 2019)

INTRODUCTION: Paget's disease of bone (PDB) is characterised by increased and disorganised bone remodelling affecting one or more skeletal sites. Complications include bone pain, deformity, deafness and pathological ...

Now showing items 1-3 of 3

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