Browsing by Author "Quilez Oliete, Javier"

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  • Ramírez, Oscar; Olalde Marquínez, Íñigo, 1987-; Berglund, Jonas; Lorente-Galdós, Belén, 1981-; Hernández Rodríguez, Jéssica, 1983-; Quilez Oliete, Javier; Webster, Matthew T; Wayne, Robert K.; Lalueza Fox, Carles, 1965-; Vilà, Carles; Marquès i Bonet, Tomàs, 1975- (BioMed Central, 2014)
    Background: Although a variety of genetic changes have been implicated in causing phenotypic differences among dogs, the role of copy number variants (CNVs) and their impact on phenotypic variation is still poorly understood. ...
  • Tamazian, Gaik; Simonov, Serguei; Dobrynin, Pavel; Makunin, Alexey; Logachev, Anton; Komissarov, Aleksey; Shevchenko, Andrey; Brukhin, Vladimir; Cherkasov, Nikolay; Svitin, Anton; Goldman, David B. (David Benjamin); Antunes, Agostinho; Quilez Oliete, Javier; Lorente-Galdós, Belén, 1981-; Alkan, Can; Marquès i Bonet, Tomàs, 1975-; Menotti-Raymond, Marylin; David, Victor A; Narfström, Kristina; O’Brien, Stephen J. (BioMed Central, 2014)
    Background. Domestic cats enjoy an extensive veterinary medical surveillance which has described nearly 250 genetic diseases analogous to human disorders. Feline infectious agents offer powerful natural models of deadly ...
  • Olade, Iñigo; Sánchez Quinto, Federico A, 1985-; Santpere Baró, Gabriel, 1981-; Rodríguez Pérez, Juan Antonio, 1985-; Quilez Oliete, Javier; Ramírez, Oscar; Marigorta, Urko M.; Fernández Callejo, Marcos; Marquès i Bonet, Tomàs, 1975-; Navarro i Cuartiellas, Arcadi, 1969-; Lalueza Fox, Carles, 1965- (Nature Research, 2014)
    Ancient genomic sequences have started to reveal the origin and the demographic impact of farmers from the Neolithic period spreading into Europe. The adoption of farming, stock breeding and sedentary societies during the ...
  • Venkatesh, Byrappa; Lorente-Galdós, Belén, 1981-; Quilez Oliete, Javier; Marquès i Bonet, Tomàs, 1975-; Warren, Wesley C. (Nature Publishing Group, 2014)
    The emergence of jawed vertebrates (gnathostomes) from jawless vertebrates was accompanied by major morphological and physiological innovations, such as hinged jaws, paired fins and immunoglobulin-based adaptive immunity. ...
  • Abascal, Federico; Corvelo, André; Cruz, Fernando; Villanueva Cañas, José Luis, 1984-; Vlasova, Anna; Marcet Houben, Marina; Prieto Barja, Pablo, 1986-; Quilez Oliete, Javier; Frias, Leonor; Ribeca, Paolo; Capella Gutiérrez, Salvador Jesús, 1985-; Câmara Ferreira, Francisco; Lowy Gallego, Ernesto; Cozzuto, Luca; Erb, Ionas; Rodríguez Ales, José Luis; Ruiz Orera, Jorge, 1988-; Reverter Comes, Ferran; Derdak, Sophia; Blanc, Julie; Gut, Marta; Lorente-Galdós, Belén, 1981-; Gut, Ivo Glynne; Guigó Serra, Roderic; Gabaldón Estevan, Juan Antonio, 1973-; Godoy, José A. (BioMed Central, 2016)
    Background: Genomic studies of endangered species provide insights into their evolution and demographic history, reveal patterns of genomic erosion that might limit their viability, and offer tools for their effective ...
  • Carbone, Lucia; Lorente-Galdós, Belén, 1981-; Fernández Callejo, Marcos; Hernández Rodríguez, Jéssica, 1983-; Quilez Oliete, Javier; Marquès i Bonet, Tomàs, 1975-; Gibbs, Richard A. (Nature Publishing Group, 2014)
    Gibbons are small arboreal apes that display an accelerated rate of evolutionary chromosomal rearrangement and occupy a key node in the primate phylogeny between Old World monkeys and great apes. Here we present the assembly ...
  • Le Dily, François; Vidal, Enrique; Cuartero, Yasmina; Quilez Oliete, Javier; Nacht, A. Silvina; Vicent, Guillermo Pablo; Carbonell-Caballero, Jose; Sharma, Priyanka; Villanueva Cañas, José Luis, 1984-; Ferrari, Roberto; De Llobet, Lara Isabel; Verde, Gaetano; Wright, Roni H.G.; Beato, Miguel (Cold Spring Harbor Laboratory Press (CSHL Press), 2019)
    In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. Here we further ...
  • Nacht, A. Silvina; Pohl, Andy, 1979-; Zaurín Quer, Roser; Soronellas, Daniel; Quilez Oliete, Javier; Sharma, Priyanka; Wright, Roni H.G.; Beato, Miguel; Vincent, Guillermo P. (Wiley-Blackwell, 2016)
    Eukaryotic gene regulation is associated with changes in chromatin compaction that modulate access to DNA regulatory sequences relevant for transcriptional activation or repression. Although much is known about the mechanism ...
  • Quilez Oliete, Javier; Guilmatre, Audrey; Garg, Paras; Highnam, Gareth; Gymrek, Melissa; Erlich, Yaniv; Joshi, Ricky S.; Mittelman, David; Sharp, Andrew J. (Oxford University Press, 2016)
    Despite representing an important source of genetic variation, tandem repeats (TRs) remain poorly studied due to technical difficulties. We hypothesized that TRs can operate as expression (eQTLs) and methylation (mQTLs) ...
  • Amat, Ramon; Böttcher, René; Le Dily, François; Vidal Ocabo, Enrique; Quilez Oliete, Javier; Cuartero, Yasmina; Beato, Miguel; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Cold Spring Harbor Laboratory Press (CSHL Press), 2019)
    Nuclear architecture is decisive for the assembly of transcriptional responses. However, how chromosome organization is dynamically modulated to permit rapid and transient transcriptional changes in response to environmental ...
  • Serres Armero, Aitor; Povolotskaya, Inna, 1986-; Quilez Oliete, Javier; Ramírez, Oscar; Santpere Baró, Gabriel, 1981-; Kuderna, Lukas F.K.; Hernández Rodríguez, Jéssica, 1983-; Fernández Callejo, Marcos; Gómez Sánchez, Daniel; Freedman, Adam H.; Fan, Zhenxin; Novembre, John; Navarro i Cuartiellas, Arcadi, 1969-; Boyko, Adam; Wayne, Robert K.; Vilà, Carles; Lorente-Galdós, Belén, 1981-; Marquès i Bonet, Tomàs, 1975- (BioMed Central, 2017)
    BACKGROUND: Whole genome re-sequencing data from dogs and wolves are now commonly used to study how natural and artificial selection have shaped the patterns of genetic diversity. Single nucleotide polymorphisms, microsatellites ...
  • Stadhouders, Ralph; Vidal Ocabo, Enrique; Serra, François; Di Stefano, Bruno, 1984-; Le Dily, François; Quilez Oliete, Javier; Gómez, Antonio; Collombet, Samuel; Berenguer, Clara; Cuartero, Yasmina; Hecht, Jochen; Filion, Guillaume; Beato, Miguel; Martí Renom, Marc A.; Graf, T. (Thomas) (Nature Publishing Group, 2018)
    Chromosomal architecture is known to influence gene expression, yet its role in controlling cell fate remains poorly understood. Reprogramming of somatic cells into pluripotent stem cells (PSCs) by the transcription factors ...