Browsing by Author "Pybus Oliveras, Marc, 1985-"

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  • Pybus Oliveras, Marc, 1985-; Dall'Olio, Giovanni Marco, 1983-; Luisi, Pierre, 1985-; Uzkudun, Manu; Carreño Torres, Angel; Pavlidis, Pavlos; Laayouni, Hafid, 1968-; Bertranpetit, Jaume, 1952-; Engelken, Johannes (Oxford University Press, 2014)
    Searching for Darwinian selection in natural populations has been the focus of a multitude of studies over the last decades. Here we present the 1000 Genomes Selection Browser 1.0 (http://hsb.upf.edu) as a resource for ...
  • Pybus Oliveras, Marc, 1985- (Universitat Pompeu Fabra, 2015-09-28)
    Detecting positive selection in genomic regions is a recurrent topic in human population genetics studies. Over the years, many positive selection tests have been implemented to highlight specific genomic patterns left by ...
  • Engelken, Johannes; Carnero-Montoro, Elena, 1985-; Pybus Oliveras, Marc, 1985-; Andrews, Glen K.; Lalueza Fox, Carles, 1965-; Comas, David, 1969-; Sekler, Israel; de la Rasilla, Marco; Rosas, Antonio; Stoneking, Mark; Valverde, M. A. (Miguel Ángel), 1963-; Vicente García, Rubén, 1978-; Bosch Fusté, Elena (Public Library of Science (PLoS), 2014)
    Extreme differences in allele frequency between West Africans and Eurasians were observed for a leucine-to-valine substitution (Leu372Val) in the human intestinal zinc uptake transporter, ZIP4, yet no further evidence was ...
  • Mattle-Greminger, Maja P.; Bilgin Sonay, Tugce; Nater, Alexander; Pybus Oliveras, Marc, 1985-; Desai, Tariq; de Valles-Ibáñez, Guillem; Casals López, Ferran; Scally, Aylwyn; Bertranpetit, Jaume, 1952-; Marquès i Bonet, Tomàs, 1975-; Van Schaik, Carel P.; Anisimova, Maria; Krützen, Michael (BioMed Central, 2018)
    Background: Integrating demography and adaptive evolution is pivotal to understanding the evolutionary history and conservation of great apes. However, little is known about the adaptive evolution of our closest relatives, ...
  • Sánchez Quinto, Federico A, 1985-; Schroeder, Hannes; Ramírez, Oscar; Ávila Arcos, María C.; Pybus Oliveras, Marc, 1985-; Olalde Marquínez, Íñigo, 1987-; Velázquez, Amhed M.V.; Prada Marcos, María Encina; Vidal Encinas, Julio Manuel; Bertranpetit, Jaume, 1952-; Orlando, Ludovic; Gilbert, M Thomas; Lalueza Fox, Carles, 1965- (Elsevier, 2012)
    The genetic background of the European Mesolithic and the extent of population replacement during the Neolithic is poorly understood, both due to the scarcity of human remains from that period and the inherent methodological ...
  • Mondal, Mayukh, 1989-; Casals López, Ferran; Xu, Tina; Dall'Olio, Giovanni Marco, 1983-; Pybus Oliveras, Marc, 1985-; Netea, Mihai G; Comas, David, 1969-; Laayouni, Hafid, 1968-; Li, Qibin; Majumder, Partha P.; Bertranpetit, Jaume, 1952- (Nature Publishing Group, 2016)
    To shed light on the peopling of South Asia and the origins of the morphological adaptations found there, we analyzed whole-genome sequences from 10 Andamanese individuals and compared them with sequences for 60 individuals ...
  • Prado Martínez, Javier, 1987-; Lorente-Galdós, Belén, 1981-; Santpere Baró, Gabriel, 1981-; Casals López, Ferran; Laayouni, Hafid, 1968-; Hernández Rodríguez, Jéssica, 1983-; Hernando Herráez, Irene, 1985-; Pybus Oliveras, Marc, 1985-; Petit, Natalia; Fernández Callejo, Marcos; Dabad, Marc; Carvalho, Tiago Loureiro de, 1987-; Melé Messeguer, Marta, 1982-; Comas, David, 1969-; Navarro i Cuartiellas, Arcadi, 1969-; Bertranpetit, Jaume, 1952-; Marquès i Bonet, Tomàs, 1975- (Nature Publishing Group, 2013)
    Most great ape genetic variation remains uncharacterized1, 2; however, its study is critical for understanding population history3, 4, 5, 6, recombination7, selection8 and susceptibility to disease9, 10. Here we sequence ...
  • Pybus Oliveras, Marc, 1985-; Luisi, Pierre, 1985-; Dall'Olio, Giovanni Marco, 1983-; Uzkudun, Manu; Laayouni, Hafid, 1968-; Bertranpetit, Jaume, 1952-; Engelken, Johannes (Oxford University Press, 2015)
    MOTIVATION: Detecting positive selection in genomic regions is a recurrent topic in natural population genetic studies. However, there is little consistency among the regions detected in several genome-wide scans using ...
  • Colonna, Vincenza; Ayub, Qasim; Cheng, Yuan; Pagani, Luca; Luisi, Pierre, 1985-; Pybus Oliveras, Marc, 1985-; Garrison, Erik; Xue, Yali; Tyler-Smith, Chris; The 1000 Genomes Project Consortium (BioMed Central, 2014)
    Background: Population differentiation has proved to be effective for identifying loci under geographically localized positive selection, and has the potential to identify loci subject to balancing selection. We have ...
  • Magri, Giuliana, 1978-; Pybus Oliveras, Marc, 1985-; Sintes, Jordi; Lligé, David; Segura-Garzón, Daniel; Bascones, Sabrina; Yeste, Ada; Grasset, Emilie K.; Gutzeit, Cindy; Uzzan, Mathieu; Ramanujam, Meera; van Zelm, Menno C.; Albero-González, Raquel; Vazquez, Ivonne; Iglesias, Mar; Serrano Figueras, Sergi; Márquez, Lucía; Mercade, Elena; Mehandru, Saurabh; Cerutti, Andrea, 1965- (Elsevier, 2017)
    Secretory immunoglobulin A (SIgA) enhances host-microbiota symbiosis, whereas SIgM remains poorly understood. We found that gut IgM+ plasma cells (PCs) were more abundant in humans than mice and clonally related to a large ...
  • Nater, Alexander; Mattle-Greminger, Maja P.; Nurcahyo, Anton; Novak, Matthew G.; de Manuel, Marc; Desai, Tariq; Groves, Colin; Pybus Oliveras, Marc, 1985-; Sonay, Tugce Bilgin; Roos, Christian; Lameira, Adriano R.; Wich, Serge A.; Askew, James; Davila-Ross, Marina; Fredriksson, Gabriella; de Valles-Ibáñez, Guillem; Casals López, Ferran; Prado Martínez, Javier, 1987-; Goossens, Benoit; Verschoor, Ernst J.; Warren, Kristin S.; Singleton, Ian; Marques, David A.; Pamungkas, Joko; Perwitasari-Farajallah, Dyah; Rianti, Puji; Tuuga, Augustine; Gut, Ivo Glynne; Gut, Marta; Orozco-terWengel, Pablo; Van Schaik, Carel P.; Bertranpetit, Jaume, 1952-; Anisimova, Maria; Scally, Aylwyn; Marquès i Bonet, Tomàs, 1975-; Meijaard, Erik; Krützen, Michael (Elsevier, 2017)
    Six extant species of non-human great apes are currently recognized: Sumatran and Bornean orangutans, eastern and western gorillas, and chimpanzees and bonobos [1]. However, large gaps remain in our knowledge of fine-scale ...
  • Cagan, Alexander; Theunert, Christoph; Laayouni, Hafid, 1968-; Santpere Baró, Gabriel, 1981-; Pybus Oliveras, Marc, 1985-; Casals López, Ferran; Prüfer, Kay; Navarro i Cuartiellas, Arcadi, 1969-; Marquès i Bonet, Tomàs, 1975-; Bertranpetit, Jaume, 1952-; Andrés Morán, Aida (Oxford University Press, 2016)
    Natural selection is crucial for the adaptation of populations to their environments. Here, we present the first global study of natural selection in the Hominidae (humans and great apes) based on genome-wide information ...
  • Melé Messeguer, Marta, 1982-; Javed, Asif; Pybus Oliveras, Marc, 1985-; Calafell i Majó, Francesc; Parida, Laxmi; Bertranpetit, Jaume, 1952-; The Genographic Consortium (Public Library of Science (PLoS), 2010)
    Recombination is one of the main forces shaping genome diversity, but the information it generates is often overlooked. A recombination event creates a junction between two parental sequences that may be transmitted to the ...
  • Luisi, Pierre, 1985-; Álvarez Ponce, David; Pybus Oliveras, Marc, 1985-; Fares, Mario A.; Bertranpetit, Jaume, 1952-; Laayouni, Hafid, 1968- (Oxford University Press, 2015)
    Genes vary in their likelihood to undergo adaptive evolution. The genomic factors that determine adaptability, however, remain poorly understood. Genes function in the context of molecular networks, with some occupying ...
  • Luisi, Pierre, 1985-; Alvarez-Ponce, David; Pybus Oliveras, Marc, 1985-; Fares, Mario A.; Bertranpetit, Jaume, 1952-; Laayouni, Hafid, 1968- (Oxford University Press, 2015)
    Genes vary in their likelihood to undergo adaptive evolution. The genomic factors that determine adaptability, however, remain poorly understood. Genes function in the context of molecular networks, with some occupying ...