Browsing by Author "Prosper, Felipe"

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  • Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation
    Vilarrasa-Blasi, Roser; Soler-Vila, Paula; Verdaguer-Dot, Núria; Russiñol, Núria; Di Stefano, Marco; Chapaprieta, Vicente; Clot, Guillem; Farabella, Irene; Cuscó Pons, Pol, 1987-; Kulis, Marta; Agirre, Xabier; Prosper, Felipe; Beekman, Renée; Beà, Sílvia; Colomer Pujol, Dolors; Stunnenberg, Hendrik G.; Gut, Ivo Glynne; Campo, Elias; Marti-Renom, Marc A.; Martin-Subero, José Ignacio (Nature Research, 2021)
    To investigate the three-dimensional (3D) genome architecture across normal B cell differentiation and in neoplastic cells from different subtypes of chronic lymphocytic leukemia and mantle cell lymphoma patients, here we ...
  • Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene epigenetically regulated
    Martínez-Calle, Nicolás; Pascual, Marien; Ordóñez, Raquel; San José-Enériz, Edurne; Kulis, Marta; Miranda, Estíbaliz; Guruceaga, Elisabeth; Segura, Víctor; Larráyoz, María José; Bellosillo Paricio, Beatriz; Calasanz, María José; Besses Raebel, Carles; Rifón, José; Martín-Subero, José Ignacio; Agirre, Xabier; Prosper, Felipe (Ferrata Storti Foundation, 2019)
    In this study we have interrogated the DNA methylome of myelofibrosis patients using high-density DNA methylation arrays. We detected 35,215 differentially methylated CpGs corresponding to 10,253 genes between myelofibrosis ...

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