Browsing by Author "Portero Otín, Manuel"

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  • Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile
    Arnoriaga Rodríguez, María; Mayneris Perxachs, Jordi; Burokas, Aurelijus, 1982-; Pérez Brocal, Vicente; Moya, Andrés; Portero Otín, Manuel; Ricart, Wifredo; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (BioMed Central, 2020)
    Background: The chaperone ClpB, a bacterial protein, is a conformational antigen-mimetic of α-melanocyte-stimulating hormone (α-MSH) implicated in body weight regulation in mice. We here investigated the potential associations ...
  • Lipidomic signature of stroke recurrence after transient ischemic attack
    Purroy, Francisco; Ois Santiago, Angel Javier; Jové, Mariona; Arque, Gloria; Sol, Joaquim; Mauri Capdevila, Gerard; Rodríguez Campello, Ana; Pamplona, Reinald; Portero Otín, Manuel; Roquer, Jaume (Nature Research, 2023)
    While TIA patients have transient symptoms, they should not be underestimated, as they could have an underlying pathology that may lead to a subsequent stroke: stroke recurrence (SR). Previously, it has been described the ...
  • Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
    Fourcade, Stéphane; Morató, Laia; Parameswaran, Janani, 1990-; Ruiz, Montserrat; Ruiz Cortés, Tatiana; Jové, Mariona; Naudí, Alba; Martínez Redondo, Paloma; Dierssen, Mara; Ferrer, Isidre; Villarroya, Francesc; Pamplona, Reinald; Vaquero, Alejandro; Portero Otín, Manuel; Pujol, Aurora, 1968- (Wiley, 2018)
    Sirtuin 2 (SIRT2) is a member of a family of NAD+ -dependent histone deacetylases (HDAC) that play diverse roles in cellular metabolism and especially for aging process. SIRT2 is located in the nucleus, cytoplasm, and ...
  • Modulation of mitochondrial and inflammatory homeostasis through RIP140 is neuroprotective in an adrenoleukodystrophy mouse model
    Ranea-Robles, Pablo; Galino, Jorge; Espinosa Blay, Lluís; Schlüter, Agatha; Ruiz, Montserrat; Calingasan, Noel Ylagan; Villarroya, Francesc; Naudí, Alba; Pamplona, Reinald; Ferrer, Isidre; Beal, M. Flint; Portero Otín, Manuel; Fourcade, Stéphane; Pujol, Aurora, 1968- (Wiley, 2022)
    Aims: Mitochondrial dysfunction and inflammation are at the core of axonal degeneration in several multifactorial neurodegenerative diseases, including multiple sclerosis, Alzheimer's disease, and Parkinson's disease. The ...
  • Presence of blastocystis in gut microbiota is associated with cognitive traits and decreased executive function
    Mayneris Perxachs, Jordi; Arnoriaga Rodríguez, María; Garre-Olmo, Josep; Puig, Josep; Ramos, Rafel; Trelis, Maria; Burokas, Aurelijus; Coll, Clàudia; Zapata-Tona, Cristina; Pedraza, Salvador; Pérez Brocal, Vicente; Ramió-Torrentà, Lluís; Ricart, Wifredo; Moya, Andrés; Jové, Mariona; Sol, Joaquim; Portero Otín, Manuel; Pamplona, Reinald; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (Nature Research, 2022)
    Growing evidence implicates the gut microbiome in cognition. Blastocystis is a common gut single-cell eukaryote parasite frequently detected in humans but its potential involvement in human pathophysiology has been poorly ...
  • REMOTE ischemic perconditioning among acute ischemic stroke patients in Catalonia: REMOTE-CAT PROJECT
    Purroy, Francisco; Arque, Gloria; Mauri, Gerard; García-Vázquez, Cristina; Vicente-Pascual, Mikel; Pereira, Cristina; Vázquez-Justes, Daniel; Torres-Querol, Coral; Vena, Ana; Abilleira, Sonia; Cardona, Pere; Forné, Carles; Jiménez-Fàbrega, Xavier; Pagola, Jorge; Portero Otín, Manuel; Portero Otín, Manuel; Rodríguez-Campello, Ana; Rovira, Alex; Martí-Fàbregas, Joan (Frontiers, 2020)
    Rationale: Remote ischemic perconditioning during cerebral ischemia (RIPerC) refers to the application of brief episodes of transient limb ischemia commonly to a limb, it represents a new safe, simple and low-cost paradigm ...

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