Browsing by Author "Pohl, Andy, 1979-"

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  • bwtool: a tool for bigWig files
    Pohl, Andy, 1979-; Beato, Miguel (Oxford University Press, 2014)
    BigWig files are a compressed, indexed, binary format for genome-wide signal data for calculations (e.g. GC percent) or experiments (e.g. ChIP-seq/RNA-seq read depth). bwtool is a tool designed to read bigWig files rapidly ...
  • Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation
    Le Dily, François; Baù, Davide; Pohl, Andy, 1979-; Vicent, Guillermo Pablo; Serra, François; Soronellas, Daniel; Castellano, Giancarlo; Wright, Roni H.G.; Ballare, Cecilia Julia; Filion, Guillaume; Marti-Renom, Marc A.; Beato, Miguel (Cold Spring Harbor Laboratory Press (CSHL Press), 2014)
    The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the distribution of ...
  • Hormone-induced repression of genes requires BRG1-mediated H1.2 deposition at target promoters
    Nacht, A. Silvina; Pohl, Andy, 1979-; Zaurín Quer, Roser; Soronellas, Daniel; Quilez Oliete, Javier; Sharma, Priyanka; Wright, Roni H.G.; Beato, Miguel; Vincent, Guillermo P. (EMBO Press, 2016)
    Eukaryotic gene regulation is associated with changes in chromatin compaction that modulate access to DNA regulatory sequences relevant for transcriptional activation or repression. Although much is known about the mechanism ...
  • Relationship between nucleosome positioning and progesterone-induced alternative splicing in breast cancer cells
    Iannone, Camilla, 1984-; Pohl, Andy, 1979-; Papasaikas, Panagiotis; Soronellas, Daniel; Vicent, Guillermo Pablo; Beato, Miguel; Valcárcel, J. (Juan) (Cold Spring Harbor Laboratory Press, 2015)
    Splicing of mRNA precursors can occur cotranscriptionally and it has been proposed that chromatin structure influences splice site recognition and regulation. Here we have systematically explored potential links between ...

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