Browsing by Author "Picón-Pagès, Pol"

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  • Picón-Pagès, Pol; Gutiérrez, Daniela A.; Barranco Almohalla, Alejandro; Crepin, Giulia; Tajes Orduña, Marta; Ill-Raga, Gerard, 1982-; Guix Ràfols, Francesc Xavier; Menéndez, Silvia; Arumí Uría, Montserrat; Vicente García, Rubén, 1978-; Álvarez, Alejandra R.; Muñoz López, Francisco José, 1964- (Hindawi, 2020)
    Alzheimer's disease (AD) is tightly linked to oxidative stress since amyloid beta-peptide (Aβ) aggregates generate free radicals. Moreover, the aggregation of Aβ is increased by oxidative stress, and the neurotoxicity ...
  • Picón-Pagès, Pol; Garcia Buendia, Joan; Muñoz López, Francisco José, 1964- (Elsevier, 2019)
    Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood flow and also has important roles in intracellular signaling in neurons from the regulation of the neuronal metabolic status to ...
  • Picón-Pagès, Pol; Bonet Martínez, Jaume, 1982-; García-García, Javier, 1982-; Garcia-Buendia, Joan; Gutierrez, Daniela; Valle, Javier; Gómez-Casuso, Carmen E.S.; Sidelkivska, Valeriya; Alvarez, Alejandra; Perálvarez Marín, Alex; Suades, Albert; Fernàndez Busquets, Xavier; Andreu Martínez, David; Vicente García, Rubén, 1978-; Oliva Miguel, Baldomero; Muñoz López, Francisco José, 1964- (Elsevier, 2019)
    Alzheimer's disease (AD) is a neurodegenerative process characterized by the accumulation of extracellular deposits of amyloid β-peptide (Aβ), which induces neuronal death. Monomeric Aβ is not toxic but tends to aggregate ...
  • Godoy Zeballos, Juan Alejandro, 1959-; Rios, Juvenal A.; Picón-Pagès, Pol; Herrera-Fernández, Víctor; Swaby, Bronte; Crepin, Giulia; Vicente García, Rubén, 1978-; Fernández-Fernández, José Manuel, 1967-; Muñoz López, Francisco José, 1964- (MDPI, 2021)
    Mitochondria play key roles in ATP supply, calcium homeostasis, redox balance control and apoptosis, which in neurons are fundamental for neurotransmission and to allow synaptic plasticity. Their functional integrity is ...
  • Hammouda, Souha; Ghzaiel, Imen; Picón-Pagès, Pol; Meddeb, Wiem; Khamlaoui, Wided; Hammami, Sonia; Muñoz López, Francisco José, 1964-; Hammami, Mohamed; Zarrouk, Amira (MDPI, 2021)
    Oxysterols are assumed to be the driving force behind numerous neurodegenerative diseases. In this work, we aimed to study the ability of 7β-hydroxycholesterol (7β-OHC) to trigger oxidative stress and cell death in human ...