Browsing by Author "Perdiguero, Eusebio, 1968-"

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  • Mann, Christopher J.; Perdiguero, Eusebio, 1968-; Kharraz, Yacine; Aguilar, Susana; Pessina, Patrizia; Serrano, Antonio L.; Muñoz Cánoves, Pura, 1962- (BioMed Central, 2011)
    The repair process of damaged tissue involves the coordinated activities of several cell types in response to local and systemic signals. Following acute tissue injury, infiltrating inflammatory cells and resident stem ...
  • Solanas, Guiomar; Oliveira Peixoto, Francisca; Perdiguero, Eusebio, 1968-; Jardí, Mercè; Ruiz Bonilla, Vanesa, 1979-; Datta, Debayan; Symeonidi, Aikaterini; Castellanos, Andrés; Welz, Patrick-Simon; Martín Caballero, Juan; Sassone-Corsi, Paolo; Muñoz Cánoves, Pura, 1962-; Aznar Benitah, Salvador (Elsevier, 2017)
    Normal homeostatic functions of adult stem cells have rhythmic daily oscillations that are believed to become arrhythmic during aging. Unexpectedly, we find that aged mice remain behaviorally circadian and that their ...
  • Segalés Dalmau, Jessica; Islam, Abul, 1978-; Kumar, Roshan; Liu, Qi-Cai; Sousa-Victor, Pedro; Dilworth, F. Jeffrey; Ballestar, Esteban; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962- (BioMed Central, 2016)
    Background: Extracellular stimuli induce gene expression responses through intracellular signaling mediators. The p38 signaling pathway is a paradigm of the mitogen-activated protein kinase (MAPK) family that, although ...
  • Perdiguero, Eusebio, 1968-; Serrano Sánchez, Antonio L.; Muñoz Cánoves, Pura, 1962- (Elsevier, 2017)
    Fibro/adipogenic progenitors (FAPs) are emerging as crucial regulators of fibrous and fat deposits during skeletal muscle regeneration. In a recent issue of Cell, Kopinke et al. (2017) report that primary cilia induce the ...
  • Pessina, Patrizia; Kharraz, Yacine; Jardí, Mercè; Fukada, So-ichiro; Serrano, Antonio L.; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962- (Elsevier, 2015)
    Preservation of cell identity is necessary for homeostasis of most adult tissues. This process is challenged every time a tissue undergoes regeneration after stress or injury. In the lethal Duchenne muscular dystrophy ...
  • Baar, Marjolein P.; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962-; de Keizer, Peter LJ (Elsevier, 2018)
    Aging is the prime risk factor for the broad-based development of diseases. Frailty is a phenotypical hallmark of aging and is often used to assess whether the predicted benefits of a therapy outweigh the risks for older ...
  • Perdiguero, Eusebio, 1968-; Sousa-Victor, Pedro; Ruiz Bonilla, Vanesa, 1979-; Jardí, Mercè; Caelles Franch, Carme; Serrano, Antonio L.; Muñoz Cánoves, Pura, 1962- (Rockefeller University Press, 2011)
    Repair of damaged tissue requires the coordinated action of inflammatory and tissue-specific cells to restore homeostasis, but the underlying regulatory mechanisms are poorly understood. In this paper, we report new roles ...
  • Ardite, Esther; Perdiguero, Eusebio, 1968-; Vidal Iglesias, Berta; Gutarra, Susana; Serrano, Antonio L.; Muñoz Cánoves, Pura, 1962- (Rockefeller University Press, 2012)
    There is a widespread awareness that the wealth of preclinical toxicity data that the pharmaceutical industry has generated in recent decades is not exploited as efficiently as it could be. Enhanced data availability for ...
  • Segalés Dalmau, Jessica; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962- (Frontiers, 2016)
    Formation of skeletal muscle fibers (myogenesis) during development and after tissue injury in the adult constitutes an excellent paradigm to investigate the mechanisms whereby environmental cues control gene expression ...
  • Bengal, Eyal; Perdiguero, Eusebio, 1968-; Serrano, Antonio L.; Muñoz Cánoves, Pura, 1962- (F1000Research, 2017)
    Adult muscle stem cells, originally called satellite cells, are essential for muscle repair and regeneration throughout life. Besides a gradual loss of mass and function, muscle aging is characterized by a decline in the ...
  • Victor, Pedro Sousa (Universitat Pompeu Fabra, 2012-02-27)
    Muscle aging, in particular, is characterized by the reduction of tissue mass and function, which are particularly prominent in geriatric individuals undergoing sarcopenia. The age-associated muscle wasting is also associated ...
  • Gómez-Del Arco, Pablo; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962-; Redondo, Juan Miguel (Elsevier, 2016)
    Heart muscle maintains blood circulation, while skeletal muscle powers skeletal movement. Despite having similar myofibrilar sarcomeric structures, these striated muscles differentially express specific sarcomere components ...