Browsing by Author "Pastor, Antonio"

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  • Pastor, Antonio; Fernández Aranda, Fernando; Fitó Colomer, Montserrat; Jiménez Murcia, Susana; Botella, Cristina; Fernández Real, Jose M.; Frühbeck, Gema; Tinahones Madueño, Francisco José; Fagundo, Ana B.; Rodríguez Rodríguez, Juan Francisco; Agüera, Zaida; Langohr, Klaus; Casanueva, Felipe F.; Torre Fornell, Rafael de la (Public Library of Science , 2016)
    The endocannabinoid (eCB) system can promote food intake by increasing odor detection in mice. The eCB system is over-active in human obesity. Our aim is to measure circulating eCB concentrations and olfactory capacity in ...
  • Rivera, Patricia; Pastor, Antonio; Arrabal, Sergio; Decara, Juan M.; Vargas, Antonio; Sánchez-Marín, Laura; Pavón, Francisco Javier; Serrano, Antonia; Bautista, Dolores; Boronat Rigol, Anna; Torre Fornell, Rafael de la; Baixeras, Elena; Lucena, Maria Isabel; Rodríguez de Fonseca, Fernando; Suárez, Juan (Frontiers, 2017)
    Protective mechanisms against drug-induced liver injury are actively being searched to identify new therapeutic targets. Among them, the anti-inflammatory N-acyl ethanolamide (NAE)-peroxisome proliferators activated receptor ...
  • Pastor, Antonio; Rodríguez-Morató, Jose, 1987-; Olesti Muñoz, Eulàlia; Pujadas Bastardes, Mitona; Pérez Mañá, Clara; Khymenets, Olha, 1974-; Fitó Colomer, Montserrat; Covas Planells, Maria Isabel; Solà, Rosa; Motilva, Maria-José; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Elsevier, 2016)
    Hydroxytyrosol (HT) from olive oil, a potent bioactive molecule with health benefits, has a poor bioavailability, its free form (free HT) being undetectable so far. This fact leads to the controversy whether attained HT ...
  • Navarro-Romero, Alba; Vázquez-Oliver, Anna; Gomis González, Maria; Garzón-Montesinos, Carlos; Falcón-Moya, Rafael; Pastor, Antonio; Martín García, Elena, 1975-; Pizarro Lozano, Mª Nieves; Busquets Garcia, Arnau, 1985-; Revest, Jean-Michel; Piazza, Pier Vincenzo; Bosch, Fatima; Dierssen, Mara; Torre Fornell, Rafael de la; Rodríguez-Moreno, Antonio; Maldonado, Rafael, 1961-; Ozaita Mintegui, Andrés, 1969- (Elsevier, 2019)
    Intellectual disability is the most limiting hallmark of Down syndrome, for which there is no gold-standard clinical treatment yet. The endocannabinoid system is a widespread neuromodulatory system involved in multiple ...
  • Saravia, Rocío; Flores de los Heros, África, 1985-; Plaza-Zabala, Ainhoa, 1982-; Busquets Garcia, Arnau, 1985-; Pastor, Antonio; Torre Fornell, Rafael de la; Di Marzo, Vicenzo; Marsicano, Giovanni; Ozaita Mintegui, Andrés, 1969-; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2017)
    BACKGROUND: Tobacco withdrawal is associated with deficits in cognitive function, including attention, working memory, and episodic memory. Understanding the neurobiological mechanisms involved in these effects is crucial ...
  • Viñals, Xavier; Moreno, Estefanía; Lanfumey, Laurence; Cordomí, Arnau; Pastor, Antonio; Torre Fornell, Rafael de la; Gasperini, Paola; Navarro, Gemma; Howell, Lesley A.; Pardo, Leonardo; Lluís, Carmen; Canela, Enric I.; McCormick, Peter J.; Maldonado, Rafael, 1961-; Robledo, Patricia, 1958- (Public Library of Science, 2015)
    Activation of cannabinoid CB1 receptors (CB1R) by delta9-tetrahydrocannabinol (THC) produces a variety of negative effects with major consequences in cannabis users that constitute important drawbacks for the use of ...
  • García Marchena, Nuria; Araos, Pedro; Pavón, Francisco Javier; Ponce, Guillermo; Pedraz, María; Serrano, Antonia; Arias, Francisco; Romero Sanchiz, Pablo; Suárez, Juan; Pastor, Antonio; Torre Fornell, Rafael de la; Torrens, Marta; Rubio, Gabriel; Rodríguez de Fonseca, Fernando (Sociedad Científica Española de Estudios sobre el Alcohol, el Alcoholismo y las otras Toxicomanías, 2017)
    La adicción al alcohol se asocia con una elevada comorbilidad psiquiátrica que complica el tratamiento, siendo necesaria una fenotipación clínica objetiva de estos pacientes para optimizar la atención y mejorar el pronóstico. ...
  • Fonseca Casals, Francina, 1972-; Torre Fornell, Rafael de la; Díaz, Laura; Pastor, Antonio; Cuyàs, Elisabet; Pizarro Lozano, Mª Nieves; Khymenets, Olha, 1974-; Farré Albaladejo, Magí; Torrens, Marta (Public Library of Science (PLoS), 2011)
    Although the efficacy of methadone maintenance treatment (MMT) in opioid dependence disorder has been well established, the influence of methadone pharmacokinetics in dose requirement and clinical outcome remains controversial. ...
  • Buckland, Genevieve; Pastor, Antonio; Lujan Barroso, Leila; González Svatetz, Carlos Alberto; Travier, Noemie; Amiano, Pilar; Huerta, José María; Agudo Trigueros, Antonio; Navarro, Carmen; Chirlaque, María Dolores; Sánchez, María José; Rodríguez Barranco, Miguel; Barricarte, Aurelio; Ardanaz Aicua, Eva; Dorronsoro, Miren; Molinuevo, Amaia; Quirós, José Ramón; Torre Fornell, Rafael de la (Wiley-Blackwell, 2017)
    SCOPE: Oleanolic acid (OA) is an important triterpenic compound found in olive oil, however little is known about its concentrations in human plasma. We aimed to determine plasma OA levels in a healthy Spanish population ...
  • Portero Tresserra, Marta; Gracia Rubio, Irene, 1986-; Cantacorps, Lídia; Pozo Mendoza, Óscar J., 1975-; Gomez-Gomez, Àlex; Pastor, Antonio; López Arnau, Raúl; Torre Fornell, Rafael de la; Valverde Granados, Olga (Elsevier, 2018)
    Childhood adversity is associated with an increased risk of mood, anxiety and substance use disorders. Maternal separation is a reliable rodent model of early life adversity that leads to depression-like symptoms, which ...
  • Rodríguez-Morató, Jose, 1987-; Boronat Rigol, Anna; Kotronoulas, Aristotelis; Pujadas Bastardes, Mitona; Pastor, Antonio; Olesti Muñoz, Eulàlia; Pérez Mañá, Clara; Khymenets, Olha, 1974-; Fitó Colomer, Montserrat; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Taylor & Francis, 2016)
    Hydroxytyrosol and tyrosol are dietary phenolic compounds present in virgin olive oil and wine. Both compounds are also endogenously synthesized in our body as byproducts of dopamine and tyramine metabolisms, respectively. ...
  • Fernández Aranda, Fernando; Sauchelli, Sarah; Pastor, Antonio; González, Marcela L.; Torre Fornell, Rafael de la; Granero, Roser; Jiménez Murcia, Susana; Baños, Rosa; Botella, Cristina; Fernández Real, Jose M.; Fernández García, José C.; Frühbeck, Gema; Gómez Ambrosi, Javier; Rodríguez, Roser; Tinahones Madueño, Francisco José; Arcelus, Jon; Fagundo, Ana B.; Agüera, Zaida; Miró, Jordi; Casanueva, Felipe F. (Public Library of Science (PLoS), 2014)
    Background: Endocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females. The aims of this cross-sectional ...
  • Fagundo, Ana B.; Jiménez Murcia, Susana; Giner Bartolomé, Cristina; Anisul Islam, Mohammed; Torre Fornell, Rafael de la; Pastor, Antonio; Casanueva, Felipe F.; Crujeiras, Ana B.; Granero, Roser; Baños, Rosa; Botella, Cristina; Fernández Real, Jose M.; Frühbeck, Gema; Gómez Ambrosi, Javier; Menchón, José M.; Tinahones Madueño, Francisco José; Fernández Aranda, Fernando (Public Library of Science, 2015)
    The prefrontal (PFC) and orbitofrontal cortex (OFC) appear to be associated with both executive functions and olfaction. However, there is little data relating olfactory processing and executive functions in humans. The ...
  • Fagundo, Ana B.; Torre Fornell, Rafael de la; Jiménez Murcia, Susana; Agüera, Zaida; Pastor, Antonio; Casanueva, Felipe F.; Granero, Roser; Baños, Rosa; Botella, Cristina; de Pino Gutiárrez, Amparo; Fernández Real, Jose M.; Fernández García, José C.; Frühbeck, Gema; Gómez Ambrosi, Javier; Menchón, José M.; Moragrega, Inés; Rodríguez, Roser; Tárrega, Salomé; Tinahones Madueño, Francisco José; Fernández Aranda, Fernando (Public Library of Science (PLoS), 2013)
    Animal studies point to an implication of the endocannabinoid system on executive functions. In humans, several studies have suggested an association between acute or chronic use of exogenous cannabinoids (Δ9-tetrahydrocannabinol) ...
  • Pérez Mañá, Clara; Farré Albaladejo, Magí; Pastor, Antonio; Fonseca Casals, Francina, 1972-; Torrens, Marta; Menoyo Colomer, Esther; Pujadas Bastardes, Mitona; Frias, Silvia; Langohr, Klaus; Torre Fornell, Rafael de la (Oxford University Press, 2017)
    AIMS: Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) are non-oxidative metabolites of alcohol that can be detected in conventional and non-conventional biological matrices for longer periods than alcohol. The ...
  • Haijen, Eline; Farré Albaladejo, Magí; Torre Fornell, Rafael de la; Pastor, Antonio; Olesti Muñoz, Eulàlia; Pizarro Lozano, Mª Nieves; Ramaekers, Johannes G.; Kuypers, Kim PC (Springer, 2018)
    BACKGROUND: Preclinical data have suggested involvement of the endocannabinoid (eCB) system in MDMA-induced memory impairment. Clinical research has shown that blockade of the 5-HT2 receptor nulls memory impairment during ...
  • Rivera, Patricia; Bindila, Laura; Pastor, Antonio; Pérez Martín, Margarita; Pavón, Francisco Javier; Serrano, Antonia; Torre Fornell, Rafael de la; Lutz, Beat; Rodríguez de Fonseca, Fernando; Suárez, Juan (Frontiers, 2015)
    Endocannabinoids participate in the control of neurogenesis, neural cell death and gliosis. The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which limits the endocannabinoid degradation, ...
  • La Porta, Carmen, 1985-; Bura, S. Andreea, 1978-; Llorente Onaindia, Jone; Pastor, Antonio; Navarrete, Francisco; García-Gutiérrez, María S.; Torre Fornell, Rafael de la; Manzanares, Jorge; Monfort, Jordi; Maldonado, Rafael, 1961- (Lippincott Williams & Wilkins, 2015)
    In this study, we investigated the role of the endocannabinoid system (ECS) in the emotional and cognitive alterations associated with osteoarthritis pain. The monosodium iodoacetate model was used to evaluate the affective ...
  • Pedraz, María; Araos, Pedro; García Marchena, Nuria; Serrano, Antonia; Romero Sanchiz, Pablo; Suárez, Juan; Castilla Ortega, Estela; Mayoral Cleries, Fermín; Ruiz, Juan Jesús; Pastor, Antonio; Barrios, Vicente; Chowen, Julie A.; Argente, Jesús; Torrens, Marta; Torre Fornell, Rafael de la; Rodríguez de Fonseca, Fernando; Pavón, Francisco Javier (Frontiers, 2015)
    There are sex differences in the progression of drug addiction, relapse, and response to therapies. Because biological factors participate in these differences, they should be considered when using biomarkers for addiction. ...
  • Busquets Garcia, Arnau, 1985-; Gomis González, Maria; Guegan, Thomas, 1983-; Agustín Pavón, Carmen; Pastor, Antonio; Mato, Susana; Pérez Samartín, A.; Matute, Carlos; Torre Fornell, Rafael de la; Dierssen, Mara; Maldonado, Rafael, 1961-; Ozaita Mintegui, Andrés, 1969- (Nature Publishing Group, 2013)
    Fragile X syndrome (FXS), the most common monogenic cause of inherited intellectual disability and autism, is caused by the silencing of the FMR1 gene, leading to the loss of fragile X mental retardation protein (FMRP), a ...