Browsing by Author "Pascual Guàrdia, Sergi, 1979-"

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  • Chalela Rengifo, Roberto José, 1985-; Gallart Gallego, Lluís; Pascual Guàrdia, Sergi, 1979-; Sancho Muñoz, Antonio; Gea Guiral, Joaquim; Orozco Levi, Mauricio (DOVE Medical Press, 2018)
    Background: Hypercapnic encephalopathy is relatively frequent in severe exacerbations of COPD (ECOPDs), with its intensity usually being evaluated through clinical scales. Bispectral index (BIS) is a relatively new technique, ...
  • Barreiro Portela, Esther; Sancho Muñoz, Antonio; Puig Vilanova, Ester, 1987-; Salazar Degracia, Anna; Pascual Guàrdia, Sergi, 1979-; Casadevall Fusté, Carme; Gea Guiral, Joaquim (American Physiological Society, 2019)
    Quadriceps muscle weakness and wasting are common comorbidities in chronic obstructive pulmonary disease (COPD). Micro-RNA expression upregulation may favor muscle mass growth and differentiation. We hypothesized that the ...
  • Pascual Guàrdia, Sergi, 1979-; Badenes Bonet, Diana; Martín-Ontiyuelo, Clara; Zuccarino, Flavio; Marín Corral, Judith; Rodríguez, Alejandro; Barreiro Portela, Esther; Gea Guiral, Joaquim (Dove Medical Press, 2017)
    BACKGROUND: Vertebral compression fractures (VCF) are common in COPD patients, with osteoporosis being the main cause. The clinical impact of VCF derives mostly from both pain and chest deformity, which may lead to ventilatory ...
  • Millares, Laura; Pascual Guàrdia, Sergi, 1979-; Montón, Concepción; García-Nuñez, Marian; Lalmolda, Cristina; Faner, Rosa; Casadevall Fusté, Carme; Setó, Laia; Capilla, Silvia; Moreno, Amàlia; Castro-Acosta, Ady Angélica; Alvarez-Martinez, Carlos José; Sibila, Oriol; Peces-Barba, Germán; Cosio, Borja G.; Agustí, Alvar; Gea Guiral, Joaquim; Monsó, Eduard (BioMed Central, 2019)
    Background: The respiratory microbiome is altered in COPD patients but its relationship with core components of the disease, such as the severity of airflow limitation, the frequency of exacerbations or the circulating ...
  • Barreiro Portela, Esther; Puig Vilanova, Ester, 1987-; Salazar Degracia, Anna; Pascual Guàrdia, Sergi, 1979-; Casadevall Fusté, Carme; Gea Guiral, Joaquim (American Physiological Society, 2018)
    Peripheral muscle weakness and mass loss are characteristic features in severe chronic obstructive pulmonary disease (COPD). We hypothesized that the phosphodiesterase (PDE)-4 inhibitor roflumilast-induced cAMP may ameliorate ...