Browsing by Author "Palumbo, Emilio"

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  • Altimiras, Francisco; Uszczynska-Ratajczak, Barbara; Cámara, Francisco; Vlasova, Anna; Palumbo, Emilio; Newhouse, Stephen; Deacon, Robert M. J.; Farias, Leandro A. E.; Hurley, Michael J.; Loyola, David E.; Vásquez, Rodrigo A.; Dobson, Richard; Guigó Serra, Roderic; Cogram, Patricia (Frontiers, 2017)
  • Rodríguez Martín, Bernardo; Palumbo, Emilio; Marco Sola, Santiago; Griebel, Thasso; Ribeca, Paolo; Alonso, Graciela; Rastrojo, Alberto; Aguado, Begoña; Guigó Serra, Roderic; Djebali, Sarah (BioMed Central, 2017)
    Background: Chimeric transcripts are commonly defined as transcripts linking two or more different genes in the genome, and can be explained by various biological mechanisms such as genomic rearrangement, read-through or ...
  • Lanzos Camaioni, Andrés Arturo; Carlevaro-Fita, Joana; Mularoni, Loris; Reverter Comes, Ferran; Palumbo, Emilio; Guigó Serra, Roderic; Johnson, Rory (Nature Publishing Group, 2017)
    Long noncoding RNAs (lncRNAs) represent a vast unexplored genetic space that may hold missing drivers of tumourigenesis, but few such “driver lncRNAs” are known. Until now, they have been discovered through changes in ...
  • Garrido-Martín, Diego; Palumbo, Emilio; Guigó Serra, Roderic; Breschi, Alessandra, 1988- (Public Library of Science (PLoS), 2018)
    We present ggsashimi, a command-line tool for the visualization of splicing events across multiple samples. Given a specified genomic region, ggsashimi creates sashimi plots for individual RNA-seq experiments as well as ...
  • Mas Ponte, David; Carlevaro-Fita, Joana; Palumbo, Emilio; Hermoso Pulido, Antonio; Guigó Serra, Roderic; Johnson, Rory (Cold Spring Harbor Laboratory Press (CSHL Press), 2017)
    The subcellular localization of long noncoding RNAs (lncRNAs) holds valuable clues to their molecular function. However, measuring localization of newly discovered lncRNAs involves time-consuming and costly experimental ...
  • Pulido-Quetglas, Carlos; Aparicio i Prat, Estel, 1986-; Arnan Ros, Carme; Polidori, Taisia; Hermoso Pulido, Antonio; Palumbo, Emilio; Ponomarenko, Julia; Guigó Serra, Roderic; Johnson, Rory (Public Library of Science (PLoS), 2017)
    CRISPR-Cas9 technology can be used to engineer precise genomic deletions with pairs of single guide RNAs (sgRNAs). This approach has been widely adopted for diverse applications, from disease modelling of individual loci, ...
  • Molnar, Cristina; Heinen, Jan Peter; Reina, José; Llamazares, Salud; Palumbo, Emilio; Breschi, Alessandra, 1988-; Gay, Marina; Villarreal, Laura; Vilaseca, Marta; Pollarolo, Giulia; González, Cayetano (American Association for the Advancement of Science (AAAS), 2019)
    The notable male predominance across many human cancer types remains unexplained. Here, we show that Drosophila l(3)mbt brain tumors are more invasive and develop as malignant neoplasms more often in males than in females. ...
  • Di Tommaso, Paolo; Palumbo, Emilio; Chatzou, Maria, 1985-; Prieto Barja, Pablo, 1986-; Heuer, Michael L.; Notredame, Cedric (PeerJ Inc., 2015)
    Genomic pipelines consist of several pieces of third party software and, because of their experimental nature, frequent changes and updates are commonly necessary thus raising serious deployment and reproducibility issues. ...
  • Chen, Lu; Breschi, Alessandra, 1988-; Guigó Serra, Roderic; Palumbo, Emilio; Rendon, Augusto (American Association for the Advancement of Science (AAAS), 2014)
    Blood cells derive from hematopoietic stem cells through stepwise fating events. To characterize gene expression programs driving lineage choice, we sequenced RNA from eight primary human hematopoietic progenitor populations ...