Browsing by Author "Paliwal, Sumit"

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  • A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer
    Kloesch, Bernhard; Ionasz, Vivien; Paliwal, Sumit; Hruschka, Natascha; Martínez de Villarreal, Jaime; Öllinger, Robert; Mueller, Sebastian; Dienes, Hans Peter; Schindl, Martin; Gruber, Elisabeth S.; Stift, Judith; Herndler-Brandstetter, Dietmar; Lomberk, Gwen A.; Seidler, Barbara; Saur, Dieter; Rad, Roland; Urrutia, Raul A.; Real, Francisco X.; Martinelli, Paola (BMJ Publishing Group, 2022)
    Objective: Molecular taxonomy of tumours is the foundation of personalised medicine and is becoming of paramount importance for therapeutic purposes. Four transcriptomics-based classification systems of pancreatic ductal ...
  • NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation
    Cobo, Isidoro; Paliwal, Sumit; Bodas, Cristina; Felipe, Irene; Melià-Alomà, Júlia; Torres, Ariadna; Martínez-Villarreal, Jaime; Malumbres, Marina; García, Fernando; Millán, Irene; Pozo, Natalia del; Park, Joo-Cheol; MacDonald, Ray J.; Muñoz, Javier; Méndez, Raúl; Real, Francisco X. (Nature Research, 2023)
    Pancreatic acinar cells rely on PTF1 and other transcription factors to deploy their transcriptional program. We identify NFIC as a NR5A2 interactor and regulator of acinar differentiation. NFIC binding sites are enriched ...

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