Browsing by Author "Palau, Núria"

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  • A combined transcriptomic and genomic analysis identifies a gene signature associated with the response to anti-TNF therapy in rheumatoid arthritis
    Aterido Ballonga, Adrià, 1990-; Cañete Crespillo, Juan de Dios; Tornero, Jesús; Blanco, Francisco; Fernández-Gutiérrez, Benjamín; Pérez-García, Carolina; Alperiz, Mercedes; Olivé, Alex; Corominas, Héctor; Martínez-Taboada, Víctor; González-Alvaro, Isidoro; Fernández-Nebro, Antonio; Erra, Alba; López Lasanta, María; López Corbeto, Mireia; Palau, Núria; Marsal, Sara; Julià, Antonio (Frontiers, 2019)
    Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients do not show ...
  • Genome-wide pathway analysis identifies genetic pathways associated with psoriasis
    Aterido Ballonga, Adrià, 1990-; Julià, Antonio; Ferrándiz, Carlos; Puig, Lluís; Fonseca, Eduardo; Fernández-López, Emilia; Dauden, Esteban; Sánchez-Carazo, José Luís; López-Estebaranz, José Luís; Moreno-Ramírez, David; Vanaclocha, Francisco; Herrera, Enrique; Cueva, Pablo de la; Dand, Nick; Palau, Núria; Alonso, Arnald; López-Lasanta, María; Tortosa, Raül; García-Montero, Andrés; Codó, Laia; Gelpí, Josep Lluís; Bertranpetit, Jaume, 1952-; Absher, Devin; Capon, Francesca; Myers, Richard M.; Barker, Jonathan N.; Marsal, Sara (Elsevier, 2016)
    Psoriasis is a chronic inflammatory disease with a complex genetic architecture. To date, the psoriasis heritability is only partially explained. However, there is increasing evidence that the missing heritability in ...
  • Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy
    Julià, Antonio; López-Lasanta, María; Blanco, Francisco; Gómez, Antonio; Haro, Isabel; Mas, Antonio Juan; Erra, Alba; García Vivar, María Luz; Monfort Faure, Jorge; Sánchez-Fernández, Simón; González, Isidoro; Alperi, Mercedes; Castellanos-Moreira, Raúl; Fernández-Nebro, Antonio; Díaz Torne, César; Palau, Núria; Lastra Borràs, Raquel; Lladós, Jordi; Sanmartí, Raimon; Marsal, Sara (BioMed Central, 2021)
    Background: blocking of the Tumor Necrosis Factor (TNF) activity is a successful therapeutic approach for 50-60% of rheumatoid arthritis (RA) patients. However, there are yet no biomarkers to stratify patients for anti-TNF ...
  • Sampling time-dependent artifacts in single-cell genomics studies
    Massoni-Badosa, Ramon; Iacono, Giovanni; Moutinho, Catia; Kulis, Marta; Palau, Núria; Marchese, Domenica, 1986-; Rodríguez Ubreva, Javier; Ballestar, Esteban; Rodríguez Esteban, Gustavo; Marsal, Sara; Aymerich, Marta; Colomer Pujol, Dolors; Campo, Elias; Julià Cano, Antoni; Martín-Subero, José Ignacio; Heyn, Holger (BioMed Central, 2020)
    Robust protocols and automation now enable large-scale single-cell RNA and ATAC sequencing experiments and their application on biobank and clinical cohorts. However, technical biases introduced during sample acquisition ...

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