Browsing by Author "Pérez-Sáez, María José"

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  • A large, international study on post-transplant glomerular diseases: the TANGO project
    Uffing, Audrey; Pérez-Sáez, María José; Riella, Leonardo V. (BioMed Central, 2018)
    BACKGROUND: Long-term outcomes in kidney transplantation (KT) have not significantly improved during the past twenty years. Despite being a leading cause of graft failure, glomerular disease (GD) recurrence remains poorly ...
  • Activation of final complement components after kidney transplantation as a marker of delayed graft function severity
    Arias Cabrales, Carlos Enrique; Riera Oliva, Marta; Pérez-Sáez, María José; Gimeno Beltran, Javier; Benito, David; Redondo Pachón, María Dolores; Burballa Tàrrega, Carla, 1988-; Crespo Barrio, Marta; Pascual Santos, Julio; Rodríguez, Eva (Oxford University Press, 2020)
    Background: Ischaemia-reperfusion (I/R) damage is a relevant cause of delayed graft function (DGF). Complement activation is involved in experimental I/R injury, but few data are available from kidney transplant (KT) ...
  • Avances en la valoración de la salud ósea en el trasplantado renal
    Pérez-Sáez, María José; Prieto-Alhambra, Daniel; Díez Pérez, Adolfo; Pascual Santos, Julio (Elsevier, 2017)
    Bone disease related to chronic kidney disease and, particularly, to kidney transplant patients is a common cause or morbidity and mortality, especially due to a higher risk of osteoporotic fractures. Despite the fact that ...
  • Clinical profiles in renal patients with COVID-19
    Arenas Jiménez, María Dolores; Crespo Barrio, Marta; Pérez-Sáez, María José; Collado Nieto, Silvia; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Barbosa Puig, Francisco; Buxeda, Anna; Burballa Tàrrega, Carla, 1988-; Sans Atxer, Laia; Vázquez, Susana; Oliveras, Anna; Mir, Marisa; Outón González, Sara; Galceran Herrera, Isabel; Solà Porta, Eulàlia; Sierra Ochoa, Adriana; Barrios Barrera, Clara; Rodriguez García, Eva; Cao Baduell, Higinio (MDPI, 2020)
    The COVID-19 pandemic has led to frequent referrals to the emergency department on suspicion of this infection in maintenance hemodialysis (MHD) and kidney transplant (KT) patients. We aimed to describe their clinical ...
  • COVID-19 in elderly kidney transplant recipients
    Crespo Barrio, Marta; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Burballa Tàrrega, Carla, 1988-; Vázquez, Susana; Mir, Marisa; Sierra Ochoa, Adriana; Collado Nieto, Silvia; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Barbosa Puig, Francisco; Cao Baduell, Higinio; Arenas Jiménez, María Dolores; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Pascual Santos, Julio (Wiley, 2020)
    The SARS-Cov-2 infection disease (COVID-19) pandemic has posed at risk the kidney transplant (KT) population, particularly the elderly recipients. From March 12 until April 4, 2020, we diagnosed COVID-19 in 16 of our 324 ...
  • COVID-19 in grade 4-5 chronic kidney disease patients
    Collado Nieto, Silvia; Arenas Jiménez, María Dolores; Barbosa Puig, Francisco; Cao Baduell, Higinio; Montero, Maria Milagro; Villar García, Judit; Barrios Barrera, Clara; Rodriguez García, Eva; Sans Atxer, Laia; Sierra Ochoa, Adriana; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Coca, Armando; Maiques LLacer, José María; Güerri Fernández, Roberto; Horcajada Gallego, Juan Pablo; Crespo Barrio, Marta; Pascual Santos, Julio (Karger (S. Karger AG), 2020)
    Introduction: Chronic kidney disease (CKD) increases the risk of mortality during coronavirus disease 2019 (COVID-19) episodes, and some reports have underlined the high incidence and severity of this infection in dialysis ...
  • Early hypertransaminasemia after kidney transplantation: significance and evolution according to donor type
    Solà Porta, Eulàlia; Redondo Pachón, María Dolores; Arias Cabrales, Carlos Enrique; Navazo, Diego; Buxeda, Anna; Burballa Tàrrega, Carla, 1988-; Crespo Barrio, Marta; García-Retortillo, Montserrat; Pascual Santos, Julio; Pérez-Sáez, María José (MDPI, 2021)
    Early hypertransaminasemia after kidney transplantation (KT) is frequent. It has been associated with the crosstalk produced between the liver and the kidney in ischemia-reperfusion situations. However, the influence of ...
  • Effect of combined gluten-free, dairy-free diet in children with steroid-resistant nephrotic syndrome: an open pilot trial
    Leon, Juliette; Pérez-Sáez, María José; Uffing, Audrey; Murakami, Naoka; Watanabe, Andreia; Cureton, Pamela; Kenyon, Victoria; Keating, Leigh; Yee, Karen; Fernandes Satiro, Carla Aline; Yu, Bryant; Bonventre, Joseph V.; Fasano, Alessio; Riella, Leonardo V. (Elsevier, 2018)
    INTRODUCTION: Steroid-resistant nephrotic syndrome (SRNS) affects both children and adults and has a high rate of progression to end-stage renal disease. Although a subset of patients have well-characterized genetic ...
  • Frailty among chronic kidney disease patients on the kidney transplant waiting list: the sex-frailty paradox
    Pérez-Sáez, María José; Arias Cabrales, Carlos Enrique; Dávalos Yerovi, Vanesa; Redondo Pachón, María Dolores; Faura, Anna; Vera, María; Bach-Pascual, Anna; Pedreira Robles, Guillermo; Junyent-Iglesias, Ernestina; Crespo Barrio, Marta; Marco, Ester; Rodríguez-Mañas, Leocadio; Pascual Santos, Julio; FRAIL-MAR Study Group (Oxford University Press, 2021)
    Background: Frailty is defined as decreased physiologic reserve and resistance to stressors that predisposes patients towards poor health results. Its prevalence in chronic kidney disease (CKD) patients who are kidney ...
  • Gender differences in cancer risk after kidney transplantation
    Buxeda, Anna; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Bartolomé, Álvaro; Mir Fontana, M. Luisa; Pascual-Dapena, Ana; Sans, Anna; Duran Jordà, Xavier, 1974-; Crespo Barrio, Marta; Pascual Santos, Julio (Impact Journals, 2019)
    Kidney transplant (KT) recipients are at greater risk of developing some cancers than the general population. Moreover, cancer is the only cause of death that is currently increasing after kidney transplantation. We analyzed ...
  • Immunological impact of a gluten-free dairy-free diet in children with kidney disease: a feasibility study
    Pérez-Sáez, María José; Pascual Santos, Julio; Riella, Leonardo V. (Frontiers, 2021)
    Kidney disease affects 10% of the world population and is associated with increased mortality. Steroid-resistant nephrotic syndrome (SRNS) is a leading cause of end-stage kidney disease in children, often failing standard ...
  • Impact of intra-abdominal pressure on early kidney transplant outcomes
    Coca, Armando; Arias Cabrales, Carlos Enrique; Pérez-Sáez, María José; Fidalgo, Verónica; González, Pablo; Acosta-Ochoa, Isabel; Lorenzo, Arturo; Rollán, María Jesús; Mendiluce, Alicia; Crespo Barrio, Marta; Pascual Santos, Julio; Bustamante-Munguira, Juan (Nature Research, 2022)
    Increased intra-abdominal pressure (IAP) is common among post-surgical patients and may cause organ dysfunction. However, its impact after kidney transplantation on early postoperative complications and graft recovery ...
  • Impact of persistent and cleared preformed HLA DSA on kidney transplant outcomes
    Redondo Pachón, María Dolores; Pérez-Sáez, María José; Mir Fontana, M. Luisa; Gimeno Beltran, Javier; Llinàs-Mallol, Laura; García, Carmen; Hernández, Juan José; Yélamos López, José; Pascual Santos, Julio; Crespo Barrio, Marta (Elsevier, 2018)
    Preformed HLA donor-specific antibodies (DSA) only detected with Luminex have been associated with increased risk of antibody-mediated rejection (ABMR) and graft failure after kidney transplantation (KT). Their evolution ...
  • Impact of preformed and de novo anti-HLA DP antibodies in renal allograft survival.
    Redondo Pachón, María Dolores; Pascual Santos, Julio; Pérez-Sáez, María José; García, Carmen; Hernández, Juan José; Gimeno Beltran, Javier; Mir Fontana, M. Luisa; Crespo Barrio, Marta (Elsevier, 2016)
    The influence of antibodies against HLA-DP antigens detected with solid-phase assays on graft survival after kidney transplantation (KT) is uncertain. We evaluated with Luminex® the prevalence of pre- and posttransplant ...
  • Increased mortality after kidney transplantation in mildly frail recipients
    Pérez-Sáez, María José; Arias Cabrales, Carlos Enrique; Redondo Pachón, María Dolores; Burballa Tàrrega, Carla, 1988-; Buxeda, Anna; Bach-Pascual, Anna; Faura, Anna; Junyent-Iglesias, Ernestina; Marco, Ester; Rodríguez-Mañas, Leocadio; Crespo Barrio, Marta; Pascual Santos, Julio; FRAIL-MAR Study Group (Oxford University Press, 2022)
    Background: physical Frailty Phenotype (PFP) is the most used frailty instrument among kidney transplant recipients, classifying patients as pre-frail if they have 1-2 criteria and as frail if they have ≥3. However, different ...
  • El Kidney Donor Profile Index: ¿se puede extrapolar a nuestro entorno?
    Pascual Santos, Julio; Pérez-Sáez, María José (Sociedad Española de Nefrologia, 2016)
    Es frecuente que nos encontremos ante el dilema de aceptar o no un riñón aparentemente no óptimo en un paciente que lleva un determinado tiempo en diálisis y desea ser trasplantado. La evaluación de la «calidad» del riñón ...
  • Kidney Transplantation in the Diabetic Patient.
    Pérez-Sáez, María José; Pascual Santos, Julio (MDPI, 2015)
    Diabetes mellitus is one of the most important causes of chronic kidney disease (CKD). In patients with advanced diabetic kidney disease, kidney transplantation (KT) with or without a pancreas transplant is the treatment ...
  • Kidney transplantation outcomes from elderly donors after circulatory death: a comparison with elderly brain-dead donors
    Buxeda, Anna; Velis, Gonzalo; Arias Cabrales, Carlos Enrique; Zapatero, Ana; Burballa Tàrrega, Carla, 1988-; Redondo Pachón, María Dolores; Mir, Marisa; Crespo Barrio, Marta; Pascual Santos, Julio; Pérez-Sáez, María José (Oxford University Press, 2020)
    Background: The use of kidneys from elderly controlled donation after circulatory death (cDCD) donors has increased significantly in recent years. Concerns about outcomes achieved with these elderly cDCD kidneys have arisen. ...
  • Long-term redistribution of peripheral lymphocyte subpopulations after switching from calcineurin to mTOR inhibitors in kidney transplant recipients
    Llinàs-Mallol, Laura; Redondo Pachón, María Dolores; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Yélamos López, José; Duran Jordà, Xavier, 1974-; Faura, Anna; López-Botet, Miguel; Pascual Santos, Julio; Crespo Barrio, Marta (MDPI, 2020)
    Classical immunosuppression based on steroids, calcineurin inhibitors, and mycophenolate results in several unwanted effects and unsatisfactory long-term outcomes in kidney transplantation (KT). New immunosuppressors search ...
  • Mammalian target of rapamycin inhibitors combined with Calcineurin inhibitors as initial immunosuppression in renal transplantation: a meta-analysis
    Montero, Núria; Quero, Maria; Melilli, Edoardo; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Bestard, Oriol; Crespo Barrio, Marta; Cruzado, Josep Ma.; Pascual Santos, Julio (Lippincott Williams & Wilkins, 2019)
    Background: The current standard of care immunosuppressive regimen in kidney transplantation (KT) includes a combination of mycophenolates (MMF/MPA) with a calcineurin inhibitor (CNI). Methods: We designed a systematic ...

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