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Browsing by Author "Ordovás, José M."

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CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial.

Corella, Dolores; Asensio, Eva María; Coltell, Oscar; Sorlí, José Vicente; Ramón, Estruch; Martínez-González, Miguel A.; Salas-Salvadó, Jordi; Castañer, Olga; Arós, Fernando; Lapetra, José; Serra-Majem, Luis; Gómez-Gracia, Enrique; Ortega‑Azorín, Carolina; Fiol, Miquel; Díez Espino, Javier; Díaz‑López, Andrés; Fitó Colomer, Montserrat; Ros, Emilio; Ordovás, José M. (Springer Verlag, 2016)

BACKGROUND: Circadian rhythms regulate key biological processes influencing metabolic pathways. Disregulation is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). Circadian rhythms are generated by ...
Epigenomic assessment of cardiovascular disease risk and interactions with traditional risk metrics

Westerman, Kenneth; Fernández Sanlés, Alba, 1988-; Patil, Prasad; Sebastiani, Paola; Jacques, Paul; Starr, John M.; Deary ,Ian J.; Liu, Qing; Liu, Simi; Elosua Llanos, Roberto; DeMeo, Dawn L; Ordovás, José M. (Wiley-Blackwell, 2020)

Background Epigenome-wide association studies for cardiometabolic risk factors have discovered multiple loci associated with incident cardiovascular disease (CVD). However, few studies have sought to directly optimize a ...
Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population

Coltell, Oscar; Asensio, Eva María; Sorlí, José Vicente; Barragán, Rocio; Fernández-Carrión, Rebeca; Portolés, Olga; Ortega-Azorín, Carolina; Martínez-LaCruz, Raul; González, José I.; Zanon-Moreno, Vicente; Gimenez-Alba, Ignacio; Ros, Emilio; Ordovás, José M.; Corella, Dolores (MDPI, 2019)

Although, for decades, increased serum bilirubin concentrations were considered a threatening sign of underlying liver disease and had been associated with neonatal jaundice, data from recent years show that bilirubin is ...
Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study.

Sayols, Sergi; Subirana Cachinero, Isaac; Lluís Ganella, Carla, 1984-; Civeira, Fernando; Roquer, Jaume; Do, AN; Absher, Devin; Cenarro, A.; Muñoz, Dani; Soriano Tarraga, Carolina; Jiménez Conde, Jordi; Ordovás, José M.; Sentí Clapés, Mariano; Aslibekyan, Stella W.; Marrugat de la Iglesia, Jaume; Arnett, Donna K.; Elosua Llanos, Roberto (Oxford University Press, 2016)

Lipid traits (total, low-densityand high-density lipoproteincholesterol, and triglycerides) are risk factors for cardiovascular disease. DNA methylation is an inherited but also modifiable epigenetic mark ...
Impact of phenol-enriched virgin olive oils on the postprandial levels of circulating microRNAs related to cardiovascular disease

Daimiel, Lidia; Micó, Víctor; Valls, Rosa M.; Pedret, Anna; Motilva, Maria-José; Rubió, Laura; Fitó Colomer, Montserrat; Farràs Mañé, Marta; Covas Planells, Maria Isabel; Solá, Rosa; Ordovás, José M. (Wiley-VCH Verlag, 2020)

Scope: We investigate the postprandial modulation of cardiovascular-related microRNAs elicited by extra virgin olive oil (EVOOs) containing different levels of their own polyphenols. Methods and results: It is randomized, ...
Physical fitness and physical activity association with cognitive function and quality of life: baseline cross-sectional analysis of the PREDIMED-Plus trial

Daimiel, Lidia; Schröder, Helmut, 1958-; Cuenca Royo, Aida Ma, 1981-; Gisbert Sellés, Cristina; Torre Fornell, Rafael de la; Ordovás, José M. (Nature Research, 2020)

Physical activity (PA) has been hypothesized to be effective to maintaining cognitive function and delay cognitive decline in the elderly, but physical fitness (PF) could be a better predictor of cognitive function. We ...
Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores

Corella, Dolores; Coltell, Oscar; Sorlí, José Vicente; Estruch, Ramón; Quiles, Laura; Martínez-González, Miguel A.; Salas Salvadó, Jordi; Castañer, Olga; Arós, Fernando; Ortega Calvo, Manuel; Serra Majem, Lluís; Gómez-Gracia, Enrique; Portolés, Olga; Fiol, Miquel; Díez Espino, Javier; Basora, Josep; Fitó Colomer, Montserrat; Ros, Emilio; Ordovás, José M. (MDPI Publishing, 2016)

Nutrigenetic studies analyzing gene-diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by ...
Sweet taste preference: Relationships with other tastes, liking for sugary foods and exploratory genome-wide association analysis in subjects with metabolic syndrome

Fernández-Carrión, Rebeca; Sorlí, José Vicente; Coltell, Oscar; Pascual, Eva C.; Ortega-Azorín, Carolina; Barragán, Rocio; Giménez-Alba, Ignacio M.; Alvarez-Sala, Andrea; Fitó Colomer, Montserrat; Ordovás, José M.; Corella, Dolores (MDPI, 2021)

Taste perception and its association with nutrition and related diseases (type 2 diabetes, obesity, metabolic syndrome, cardiovascular, etc.) are emerging fields of biomedicine. There is currently great interest in ...

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Browsing by Author "Ordovás, José M."

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