Browsing by Author "Olea, Nicolás"

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  • Changes in the total effective xenoestrogen burden (TEXB) of breast cancer patients during an 18-month post-surgical follow-up
    Fernandez, Mariana F.; Pumarega Rodríguez, José Antonio; Porta Serra, Miquel; Molina-Molina, Jose Manuel; Arrebola, Juan Pedro; Olea, Nicolás (Elsevier, 2017)
    We aimed to assess changes in the total effective xenoestrogen burden (TEXB) -a biomarker of combined effect of mixtures of xenoestrogens- in breast cancer patients at surgery (breast adipose tissue) and at different time ...
  • Genome-wide DNA methylation study in human placenta identifies novel loci associated with maternal smoking during pregnancy
    Morales, Eva; Vilahur Chiaraviglio, Nadia, 1982-; Salas Díaz, Lucas Andrés, 1980-; Motta, Valeria; Fernandez, Mariana F.; Murcia, Mario; Llop, Sabrina; Tardón, Adonina; Fernandez-Tardon, Guillermo; Santa Marina, Loreto; Gallastegui, Mara; Bollati, Valentina; Estivill, Xavier, 1955-; Olea, Nicolás; Sunyer Deu, Jordi; Bustamante Pineda, Mariona (Oxford University Press, 2016)
    BACKGROUND: We conducted an epigenome-wide association study (EWAS) of DNA methylation in placenta in relation to maternal tobacco smoking during pregnancy and examined whether smoking-induced changes lead to low birthweight. ...
  • In utero exposure to mixtures of xenoestrogens and child neuropsychological development
    Vilahur Chiaraviglio, Nadia, 1982-; Fernandez, Mariana F.; Bustamante Pineda, Mariona; Ramos, Rosa; Forns i Guzman, Joan, 1981-; Ballester Díez, Ferran; Murcia, Mario; Riaño, Isolina; Ibarluzea, Jesús; Olea, Nicolás; Sunyer Deu, Jordi (Elsevier, 2014)
    BACKGROUND: To date, no epidemiological studies have explored the impact and persistence of in utero exposure to mixtures of xenoestrogens on the developing brain. We aimed to assess whether the cumulative effect of ...
  • Prenatal exposure to mixtures of xenoestrogens and genome-wide DNA methylation in human placenta
    Vilahur Chiaraviglio, Nadia, 1982-; Bustamante Pineda, Mariona; Morales, Eva; Motta, Valeria; Fernandez, Mariana F.; Salas, Lucas A.; Escaramís, Geòrgia; Ballester Díez, Ferran; Murcia, Mario; Tardón, Adonina; Riaño, Isolina; Santa Marina, Loreto; Ibarluzea, Jesús; Arrebola, Juan Pedro; Estivill, Xavier, 1955-; Bollati, Valentina; Sunyer Deu, Jordi; Olea, Nicolás (Future Medicine, 2016)
    BACKGROUND: In utero exposure to xenostrogens may modify the epigenome. We explored the association of prenatal exposure to mixtures of xenoestrogens and genome-wide placental DNA methylation. MATERIALS & METHODS: Sex-specific ...
  • Prenatal exposure to mixtures of xenoestrogens and repetitive element DNA methylation changes in human placenta
    Vilahur Chiaraviglio, Nadia, 1982-; Bustamante Pineda, Mariona; Byun, Hyang-Min; Fernandez, Mariana F.; Santa Marina, Loreto; Basterrechea, Mikel; Ballester Díez, Ferran; Murcia, Mario; Tardón, Adonina; Fernández Somoano, Ana; Estivill, Xavier, 1955-; Olea, Nicolás; Sunyer Deu, Jordi; Baccarelli, Andrea A. (Elsevier, 2014)
    BACKGROUND: Prenatal exposure to endocrine disrupting compounds (EDCs) has previously shown to alter epigenetic marks. OBJECTIVES: In this work we explore whether prenatal exposure to mixtures of xenoestrogens has the ...
  • Total effective xenoestrogen burden in serum samples and risk for breast cancer in a population-based multicase-control study in Spain.
    Pastor-Barriuso, Roberto; Fernandez, Mariana F.; Castaño Vinyals, Gemma; Whelan, Denis ; Pérez-Gómez, Beatriz; Llorca, Javier; Villanueva Belmonte, Cristina; Guevara, Marcela; Molina-Molina, Jose Manuel; Artacho-Cordón, Francisco; Barriuso-Lapresa, Laura; Tusquets Trias de Bes, Ignacio; Dierssen Sotos, Trinidad; Aragonés, Núria; Olea, Nicolás; Kogevinas, Manolis; Pollan, Marina (National Institute of Environmental Health Sciences, 2016)
    BACKGROUND: Most studies on endocrine-disrupting chemicals and breast cancer have focused on single compounds and have produced inconclusive findings. OBJECTIVES: We assessed the combined estrogenic effects of mixtures of ...

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