Browsing by Author "Nadal i Roura, Xavier, 1980-"

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  • Crucial role of CB(2) cannabinoid receptor in the regulation of central immune responses during neuropathic pain
    Racz, Ildiko; Nadal i Roura, Xavier, 1980-; Alferink, Judith; Baños i Díez, Josep Eladi; Rehnelt, Jennifer; Martín Sánchez, Miquel, 1971-; Pintado, Belén; Gutierrez-Adan, Alfonso; Sanguino, Elena; Manzanares, Jorge; Zimmer, Andreas; Maldonado, Rafael, 1961- (Society for Neuroscience, 2008)
    Neuropathic pain is a clinical manifestation of nerve injury difficult to treat even with potent analgesic compounds. Here, we used different lines of genetically modified mice to clarify the role played by CB2 cannabinoid ...
  • Interferon-gamma is a critical modulator of CB(2) cannabinoid receptor signaling during neuropathic pain
    Racz, Ildiko; Nadal i Roura, Xavier, 1980-; Alferink, Judith; Baños i Díez, Josep Eladi; Rehnelt, Jennifer; Martín, Miguel; Pintado, Belén; Gutierrez-Adan, Alfonso; Sanguino, Elena; Bellora Pereyra, Nicolás; Manzanares, Jorge; Zimmer, Andreas; Maldonado, Rafael, 1961- (Society for Neuroscience, 2008)
    Nerve injuries often lead to neuropathic pain syndrome. The mechanisms contributing to this syndrome involve local inflammatory responses, activation of glia cells, and changes in the plasticity of neuronal nociceptive ...
  • Long-lasting oral analgesic effects of N-protected aminophosphinic dual ENKephalinase inhibitors (DENKIs) in peripherally controlled pain
    Bonnard, Elisabeth; Poras, Hervé; Nadal i Roura, Xavier, 1980-; Maldonado, Rafael, 1961-; Fournié-Zaluski, Marie-Claude; Roques, Bernard P. (Wiley Open Access, 2015)
    The peripheral endogenous opioid system is critically involved in neuropathic and inflammatory pain generation as suggested by the modulation of opioid receptors expression and enkephalins (ENKs) release observed in these ...
  • Participation of the endogenous opioid and cannabinoid systems in neuropathic pain
    Nadal i Roura, Xavier, 1980- (Universitat Pompeu Fabra, 2011-09-23)
    This work is focused in the study of the pathophysiology of neuropathic pain, particularly in the role of the endogenous opioid and cannabinoid systems. Neuropathic pain is a chronic illness with a high prevalence in the ...