Browsing by Author "Munteanu, Andreea"

Sort by: Order: Results:

  • A spectrum of modularity in multi‐functional gene circuits
    Jiménez, Alba; Cotterell, James; Munteanu, Andreea; Sharpe, James (EMBO Press, 2017)
    A major challenge in systems biology is to understand the relationship between a circuit's structure and its function, but how is this relationship affected if the circuit must perform multiple distinct functions within ...
  • Avoiding transcription factor competition at promoter level increases the chances of obtaining oscillations
    Munteanu, Andreea; Constante Pereira, Marco; Isalan, Mark; Solé Vicente, Ricard, 1962- (BioMed Central, 2010)
    Background: The ultimate goal of synthetic biology is the conception and construction of genetic circuits that are reliable with respect to their designed function (e.g. oscillators, switches). This task remains still to ...
  • Design principles of stripe-forming motifs: the role of positive feedback
    Munteanu, Andreea; Cotterell, James; Solé Vicente, Ricard, 1962-; Sharpe, James (Nature Publishing Group, 2014)
    Interpreting a morphogen gradient into a single stripe of gene-expression is a fundamental unit of patterning in early embryogenesis. From both experimental data and computational studies the feed-forward motifs stand out ...
  • Dynamics of gene circuits shapes evolvability
    Jiménez, Alba; Cotterell, James; Munteanu, Andreea; Sharpe, James (Cold Spring Harbor Laboratory Press, 2015)
    To what extent does the dynamical mechanism producing a specific biological phenotype bias the ability to evolve into novel phenotypes? We use the interpretation of a morphogen gradient into a single stripe of gene expression ...
  • Human synthetic lethal inference as potential anti-cancer target gene detection
    Conde Pueyo, Núria, 1983-; Munteanu, Andreea; Solé Vicente, Ricard, 1962-; Rodríguez Caso, Carlos (BioMed Central, 2009)
    Background: Two genes are called synthetic lethal (SL) if mutation of either alone is not lethal, but mutation of both leads to death or a significant decrease in organism's fitness. The detection of SL gene pairs constitutes ...
  • On the relationship between structure and function of gene circuits : Study of evolvability and multi-functionality
    Jiménez Asins, Alba (Universitat Pompeu Fabra, 2016-12-14)
    Per tal d'estudiar la relació complexa entre l'estructura d'un circuit genètic i la seva funció, ens centrem en estudiar dues proprietas: la seva capacitat evolutiva i la seva multi-functionalitat. Primer, fins a quin punt ...

Search DSpace

Browse

My Account

In collaboration with Compliant to Partaking