Browsing by Author "Morris, Quaid"

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  • Jiao, Wei; Atwal, Gurnit; Polak, Paz; Karlic, Rosa; Cuppen, Edwin; PCAWG Tumor Subtypes and Clinical Translation Working Group; Danyi, Alexandra; Ridder, Jeroen de; van Herpen, Carla; Lolkema, Martijn P.; Steeghs, Neeltje; Getz, Gad; Morris, Quaid; Stein, Lincoln D.; PCAWG Consortium; Stobbe, Miranda D. (Nature Research, 2020)
    In cancer, the primary tumour's organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as ...
  • Solana, Jordi; Irimia Martínez, Manuel; Ayoub, Salah; Rodriguez Orejuela, Marta; Zywitza, Vera; Jens, Marvin; Tapial Rodríguez, Javier, 1990-; Ray, Debashish; Morris, Quaid; Hughes, Timothy R.; Blencowe, Benjamin J.; Rajewsky, Nicolaus (eLife, 2016)
    In contrast to transcriptional regulation, the function of alternative splicing (AS) in stem cells is poorly understood. In mammals, MBNL proteins negatively regulate an exon program specific of embryonic stem cells; ...
  • Spruce, Thomas; Plass Pórtulas, Mireya, 1982-; Gohr, André; Ray, Debashish; Martínez de Lagrán Cabredo, María; Rot, Gregor; Nóvoa, Ana; Burguera, Demián; Permanyer, Jon; Miret-Cuesta, Marta; Zheng, Hong; Swanson, Maurice S.; Morris, Quaid; Mallo, Moises; Dierssen, Mara; Hughes, Timothy R.; Pernaute, Barbara; Irimia Martínez, Manuel (Public Library of Science (PLoS), 2022)
    Understanding the regulatory interactions that control gene expression during the development of novel tissues is a key goal of evolutionary developmental biology. Here, we show that Mbnl3 has undergone a striking process ...

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