Browsing by Author "Moro, Simone G."

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  • Extensive post-transcriptional buffering of gene expression in the response to severe oxidative stress in baker's yeast
    Blevins, William Robert, 1987-; Tavella, Teresa; Moro, Simone G.; Blasco Moreno, Bernat, 1986-; Closa-Mosquera, Adrià; Díez Antón, Juana, 1962-; Carey, Lucas, 1980-; Albà Soler, Mar (Nature Research, 2019)
    Cells responds to diverse stimuli by changing the levels of specific effector proteins. These changes are usually examined using high throughput RNA sequencing data (RNA-Seq); transcriptional regulation is generally assumed ...
  • Impact of uORFs in mediating regulation of translation in stress conditions
    Moro, Simone G.; Hermans, Cedric; Ruiz Orera, Jorge, 1988-; Albà Soler, Mar (BioMed Central, 2021)
    Background: A large fraction of genes contains upstream ORFs (uORFs) in the 5' untranslated region (5'UTR). The translation of uORFs can inhibit the translation of the main coding sequence, for example by causing premature ...
  • Native RNA sequencing in fission yeast reveals frequent alternative splicing isoforms
    Montañés, José Carlos; Huertas, Marta; Moro, Simone G.; Blevins, William Robert, 1987-; Carmona, Mercè; Ayté del Olmo, José; Hidalgo Hernando, Elena; Albà Soler, Mar (Cold Spring Harbor Laboratory Press (CSHL Press), 2022)
    The unicellular yeast Schizosaccharomyces pombe (fission yeast) retains many of the splicing features observed in humans and is thus an excellent model to study the basic mechanisms of splicing. Nearly half the genes contain ...