Browsing by Author "Moreno Mateos, Miguel Ángel"

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  • Vicencio, Jeremy, 1990-; Sánchez-Bolaños, Carlos; Moreno-Sánchez, Ismael; Brena, David; Vejnar, Charles E.; Kukhtar, Dmytro; Ruiz-López, Miguel; Cots-Ponjoan, Mariona; Rubio, Alejandro; Rodrigo Melero, Natalia; Crespo-Cuadrado, Jesús; Carolis, Carlo; Pérez-Pulido, Antonio J.; Giráldez, Antonio; Kleinstiver, Benjamin P.; Cerón Madrigal, Julián; Moreno Mateos, Miguel Ángel (Nature Research, 2022)
    The requirement for Cas nucleases to recognize a specific PAM is a major restriction for genome editing. SpCas9 variants SpG and SpRY, recognizing NGN and NRN PAMs, respectively, have contributed to increase the number of ...
  • Fernández, Juan Pablo; Moreno Mateos, Miguel Ángel; Gohr, André; Miao, Liyun; Chan, Shun Hang; Irimia Martínez, Manuel; Giraldez, Antonio J. (Public Library of Science (PLoS), 2018)
    Pre-mRNA splicing is a critical step of gene expression in eukaryotes. Transcriptome-wide splicing patterns are complex and primarily regulated by a diverse set of recognition elements and associated RNA-binding proteins. ...

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