Visualitza per autoria "Moreno, Víctor"

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  • Adherence to nutrition-based cancer prevention guidelines and breast, prostate and colorectal cancer risk in the MCC-Spain case-control study
    Romaguera Bosch, Dora; Gracia Lavedan, Esther; Molinuevo, Amaia; De Batlle, Jordi; Mendez, Michelle A.; Moreno, Víctor; Vidal, Carmen; Castelló, Adela; Pérez-Gómez, Beatriz; Martín Sánchez, Vicente; Molina, Antonio J.; Dávila-Batista, Verónica; Dierssen Sotos, Trinidad; Gómez-Acebo, Inés; Llorca, Javier; Guevara, Marcela; Castilla, Jesús; Urtiaga, Carmen; Llorens-Ivorra, Cristóbal; Fernández-Tardón, Guillermo; Tardón, Adonina; Lorca Marín, José Andrés; Marcos-Gragera, Rafael; Huerta, José María; Olmedo-Requena, Rocío; Jiménez-Moleón, José Juan; Altzibar, Jone Miren; de Sanjosé, Silvia; Pollan, Marina; Aragonés, Núria; Castaño Vinyals, Gemma; Kogevinas, Manolis; Amiano, Pilar (Wiley, 2017)
    Prostate, breast and colorectal cancer are the most common tumours in Spain. The aim of the present study was to evaluate the association between adherence to nutrition-based guidelines for cancer prevention and prostate, ...
  • Association of occupational heat exposure and colorectal cancer in the MCC-Spain study
    Hinchliffe, Alice; Kogevinas, Manolis; Molina, Antonio J.; Moreno, Víctor; Aragonés, Núria; Castaño Vinyals, Gemma; Jiménez Moleón, José Juan; Gómez Acebo, Inés; Ederra, María; Amiano, Pilar; Molina-Barceló, Ana; Fernandez-Tardon, Guillermo; Alguacil Ojeda, Juan; Chirlaque, María Dolores; Hernández-Segura, Natalia; Pérez-Gómez, Beatriz; Pollan, Marina; Turner, Michelle C. (Nordic Association of Occupational Safety and Health (NOROSH), 2023)
    Objective: Heat exposure and heat stress/strain is a concern for many workers. There is increasing interest in potential chronic health effects of occupational heat exposure, including cancer risk. We examined potential ...
  • Circulating miRNAs signature on breast cancer: the MCC-Spain project
    Gómez-Acebo, Inés; Llorca, Javier; Alonso-Molero, Jéssica; Díaz-Martínez, Marta; Pérez-Gómez, Beatriz; Amiano, Pilar; Belmonte, Thalía; Molina, Antonio J.; Burgui, Rosana; Castaño Vinyals, Gemma; Moreno, Víctor; Molina-Barceló, Ana; Marcos-Gragera, Rafael; Kogevinas, Manolis; Pollán, Marina; Dierssen Sotos, Trinidad (BioMed Central, 2023)
    Purpose: To build models combining circulating microRNAs (miRNAs) able to identify women with breast cancer as well as different types of breast cancer, when comparing with controls without breast cancer. Method: miRNAs ...
  • Cohort profile: the MCC-Spain follow-up on colorectal, breast and prostate cancers: study design and initial results
    Alonso-Molero, Jéssica; Molina, Antonio J.; Jiménez-Moleón, José Juan; Pérez-Gómez, Beatriz; Martín, Vicente; Moreno, Víctor; Amiano, Pilar; Ardanaz Aicua, Eva; Sanjosé Llongueras, Silvia de; Salcedo-Bellido, Inmaculada; Fernández-Tardón, Guillermo; Alguacil Ojeda, Juan; Salas, Dolores; Marcos-Gragera, Rafael; Chirlaque, María Dolores; Aragonés, Núria; Castaño Vinyals, Gemma; Pollan, Marina; Kogevinas, Manolis; Llorca, Javier (BMJ Publishing Group, 2019)
    Purpose: Since 2016, the multicase-control study in Spain (MCC-Spain) has focused towards the identification of factors associated with cancer prognosis. Inception cohorts of patients with colorectal, breast and prostate ...
  • Common polymorphic inversions at 17q21.31 and 8p23.1 associate with cancer prognosis
    Ruiz-Arenas, Carlos; Cáceres, Alejandro; Moreno, Víctor; González, Juan Ramón (BioMed Central, 2019)
    Background: Chromosomal inversions are structural genetic variants where a chromosome segment changes its orientation. While sporadic de novo inversions are known genetic risk factors for cancer susceptibility, it is unknown ...
  • Differential mortality and the excess rates of hip fracture associated with Type 2 Diabetes: accounting for competing risks in fracture prediction matters
    Tebé, Cristian; Martínez-Laguna, Daniel; Moreno, Víctor; Cooper, Cyrus; Diez-Perez, Adolfo; Collins, Gary S.; Prieto-Alhambra, Daniel (Wiley, 2018)
    Type 2 diabetes (T2DM) is associated with a reduced life expectancy. The latest published evidence suggests an increased risk of fractures among T2DM patients. We conducted a population-based cohort study to determine the ...
  • DNA methylation levels and long-term trihalomethane exposure in drinking water: an epigenome-wide association study.
    Salas, Lucas A.; Bustamante Pineda, Mariona; González Ruiz, Juan Ramón; Gracia Lavedan, Esther; Moreno, Víctor; Kogevinas, Manolis; Villanueva Belmonte, Cristina (Taylor & Francis, 2015)
    Trihalomethanes (THM) are undesired disinfection byproducts (DBPs) formed during water treatment. Mice exposed to DBPs showed global DNA hypomethylation and c-myc and c-jun gene-specific hypomethylation, while evidence of ...
  • Expression of endoplasmic reticulum stress proteins is a candidate marker of brain metastasis in both ErbB-2+ and ErbB-2- primary breast tumors
    Sanz Pamplona, Rebeca; Aragüés Peleato, Ramón; Driouch, Keltouma; Martín, Berta; Oliva Miguel, Baldomero; Gil, Miguel; Boluda, Susana; Fernández, Pedro Luís; Martínez, Antonio; Moreno, Víctor; Acebes, Juan José; Lidereau, Rosette; Reyal, Fabien; Van De Vijver, Marc Joan; Sierra, Angels (Elsevier, 2011)
    The increasing incidence of breast cancer brain metastasis in patients with otherwise well-controlled systemic cancer is a key challenge in cancer research. It is necessary to understand the properties of brain-tropic tumor ...
  • FN14 and GRP94 expression are prognostic/predictive biomarkers of brain metastasis outcome that open up new therapeutic strategies
    Martínez Aranda, Antonio; Hernández, Vanessa; Güney, Emre, 1983-; Muixí, Laia; Foj, Ruben; Baixeras, Núria; Cuadras, Daniel; Moreno, Víctor; Urruticoechea, Ander; Gil, Miguel; Oliva Miguel, Baldomero; Moreno, Ferran; González Suárez, Eva; Vidal, Noemí; Andreu, Xavier; Seguí, Miquel A.; Ballester, Rosa; Castella, Eva; Sierra, Angels (Impact Journals, 2015)
    Brain metastasis is a devastating problem in patients with breast, lung and melanoma tumors. GRP94 and FN14 are predictive biomarkers over-expressed in primary breast carcinomas that metastasized in brain. To further ...
  • Genetic and genomic analysis modeling of germline c-MYC overexpression and cancer susceptibility
    Solé, Xavier; Hernández, Pilar; López de Heredia, Miguel de; Armengol i Dulcet, Lluís; Rodríguez Santiago, Benjamín; Gómez, Laia; Maxwell, Christopher A.; Aguilo, Fernando; Condom, Enric; Abril, Jesús; Pérez Jurado, Luis Alberto; Estivill, Xavier, 1955-; Nunes, Virginia; Capellá, Gabriel; Gruber, Stephen B.; Moreno, Víctor; Pujana, Miguel Angel (BioMed Central, 2008)
    Background: Germline genetic variation is associated with the differential expression of many human genes. The phenotypic effects of this type of variation may be important when considering susceptibility to common genetic ...
  • Long-term exposure to nitrate and trihalomethanes in drinking water and prostate cancer: a multicase–control study in Spain (MCC-Spain)
    Donat-Vargas, Carolina; Kogevinas, Manolis; Castaño Vinyals, Gemma; Pérez-Gómez, Beatriz; Llorca, Javier; Vanaclocha-Espi, Mercedes; Fernandez-Tardon, Guillermo; Costas, Laura; Aragonés, Núria; Gómez-Acebo, Inés; Moreno, Víctor; Pollan, Marina; Villanueva, Cristina M. (National Institute of Environmental Health Sciences, 2023)
    Nitrate and trihalomethanes (THMs) in drinking water are widespread and are potential human carcinogens. We evaluated the association between drinking-water exposure to nitrate and THMs and prostate cancer. During the ...
  • Mendelian randomization analysis rules out disylipidaemia as colorectal cancer cause
    Ibáñez-Sanz, Gemma; Bustamante Pineda, Mariona; Castaño Vinyals, Gemma; Kogevinas, Manolis; Moreno, Víctor (Nature Research, 2019)
    Dyslipidemia and statin use have been associated with colorectal cancer (CRC), but prospective studies have shown mixed results. We aimed to determine whether dyslipidemia is causally linked to CRC risk using a Mendelian ...
  • Physical activity domains and risk of gastric adenocarcinoma in the MCC-Spain case-control study.
    Huerta, José María; Chirlaque, María Dolores; Molina, Antonio J.; Amiano, Pilar; Martín Sánchez, Vicente; Fernández-Villa, Tania; Pérez-Gómez, Beatriz; Moreno, Víctor; Burgui, Rosana; Gómez-Acebo, Inés; Ramos-Lora, Manuel; Fernández-Tardón, Guillermo; Peiró, Rosana; Olmedo-Requena, Rocío; Pollan, Marina; Kogevinas, Manolis; Castaño Vinyals, Gemma; Aragonés, Núria; Navarro, Carmen (Public Library of Science (PLoS), 2017)
    BACKGROUND:Evidence for a protective role of physical activity against development of stomach cancer is yet inconclusive. We studied the association of domain-specific physical activity and the risk of gastric adenocarcinoma ...
  • Population-based multicase-control study in common tumors in Spain (MCC-Spain): rationale and study design
    Castano-Vinyals, Gemma; Aragonés, Núria; Pérez-Gómez, Beatriz; Martín, Vicente; Llorca, Javier; Moreno, Víctor; Altzibar, Jone Miren; Ardanaz, Eva; Sanjosé Llongueras, Silvia de; Jiménez-Moleón, José Juan; Tardón, Adonina; Alguacil, Juan; Peiró, Rosana; Marcos-Gragera, Rafael; Navarro, Carmen; Pollán, Marina; Kogevinas, Manolis; MCC-Spain Study Group (Elsevier, 2015)
    Introduction. We present the protocol of a large population-based case-control study of 5 common tumors in Spain (MCC-Spain) that evaluates environmental exposures and genetic factors. Methods. Between 2008-2013, 10,183 ...
  • Possible role of chondroitin sulphate and glucosamine for primary prevention of colorectal cancer. Results from the MCC-Spain study
    Ibáñez-Sanz, Gemma; Gracia Lavedan, Esther; Castaño Vinyals, Gemma; Kogevinas, Manolis; Moreno, Víctor (Nature Research, 2018)
    A safe and effective colorectal cancer (CRC) chemoprevention agent remains to be discovered. We aim to evaluate the association between the use of glucosamine and/or chondroitin sulphate and risk of colorectal cancer (CRC) ...
  • Reproductive risk factors in breast cancer and genetic hormonal pathways: a gene-environment interaction in the MCC-Spain project
    Dierssen Sotos, Trinidad; Palazuelos, Camilo; Jiménez-Moleón, José Juan; Aragonés, Núria; Altzibar, Jone Miren; Castaño Vinyals, Gemma; Martín Sánchez, Vicente; Gómez-Acebo, Inés; Guevara, Marcela; Tardón, Adonina; Pérez-Gómez, Beatriz; Amiano, Pilar; Moreno, Víctor; Molina, Antonio J.; Alonso Molero, Jessica; Moreno-Iribas, Conchi; Kogevinas, Manolis; Pollan, Marina; Llorca, Javier (BioMed Central, 2018)
    BACKGROUND: Reproductive factors are well known risk factors for breast cancer; however, little is known about how genetic variants in hormonal pathways interact with that relationship. METHODS: One thousand one hundred ...
  • Risk model for colorectal cancer in spanish population using environmental and genetic factors: results from the MCC-Spain study
    Ibáñez-Sanz, Gemma; Bustamante Pineda, Mariona; Espinos, Anna; Castaño Vinyals, Gemma; Kogevinas, Manolis; Moreno, Víctor (Nature Publishing Group, 2017)
    Colorectal cancer (CRC) screening of the average risk population is only indicated according to age. We aim to elaborate a model to stratify the risk of CRC by incorporating environmental data and single nucleotide ...
  • Risk Model for Prostate Cancer Using Environmental and Genetic Factors in the Spanish Multi-Case-Control (MCC) Study
    Gómez-Acebo, Inés; Dierssen Sotos, Trinidad; Fernández-Navarro, Pablo; Palazuelos, Camilo; Moreno, Víctor; Aragonés, Núria; Castaño Vinyals, Gemma; Jiménez-Moleón, José Juan; Ruiz-Cerdá, Jose Luis; Pérez-Gómez, Beatriz; Ruiz Dominguez, José Manuel; Alonso Molero, Jessica; Pollan, Marina; Kogevinas, Manolis; Llorca, Javier (Nature Publishing Group, 2017)
    Prostate cancer (PCa) is the second most common cancer among men worldwide. Its etiology remains largely unknown compared to other common cancers. We have developed a risk stratification model combining environmental factors ...
  • Sleep duration and napping in relation to colorectal and gastric cancer in the MCC-Spain study
    Papantoniou, Kyriaki, 1983-; Castaño Vinyals, Gemma; Espinosa Díaz, Ana; Turner, Michelle C.; Kogevinas, Manolis; Moreno, Víctor (Nature Research, 2021)
    Sleep duration is a novel and potentially modifiable risk factor for cancer. We evaluated the association of self-reported sleep duration and daytime napping with odds of colorectal and gastric cancer. We included 2008 ...
  • Type 2 Diabetes, antidiabetic medications, and colorectal cancer risk: two case-control studies from Italy and Spain
    Rosato, Valentina; Tavani, Alessandra; Gràcia Lavedan, Esther; Guinó, Elisabet; Castaño Vinyals, Gemma; Villanueva Belmonte, Cristina; Kogevinas, Manolis; Polesel, Jerry; Serraino, Diego; Pisa, Federica; Barbone, Fabio; Moreno, Víctor; La Vecchia, Carlo; Bosetti, Cristina (Frontiers, 2016)
    BACKGROUND: Type 2 diabetes mellitus has been associated with an excess risk of colorectal cancer, although the time-risk relationship is unclear, and there is limited information on the role of antidiabetic medications. ...

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