Browsing by Author "Morales, Hernán G."

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  • Breaking the state of the heart: meshless model for cardiac mechanics
    Lluch Alvarez, Èric; Craene, Mathieu de; Bijnens, Bart; Sermesant, Maxime; Noailly, Jérôme; Camara, Oscar; Morales, Hernán G. (Springer, 2019)
    Cardiac modeling has recently emerged as a promising tool to study pathophysiology mechanisms and to predict treatment outcomes for personalized clinical decision support. Nevertheless, achieving convergence under large ...
  • Endovascular coiling and its influence on intra-aneurysmal hemodynamics by image-based modeling
    Morales, Hernán G. (Universitat Pompeu Fabra, 2012-09-28)
    Nowadays, most popular therapies for cerebral aneurysms are clipping and coiling. Nonetheless, it is not easy to elucidate which therapeutic option is the most suitable and reliable for a patient-specific aneurysm. To face ...
  • From pixels to particles: multi-physics meshless model of the heart
    Lluc Álvarez, Èric (Universitat Pompeu Fabra, 2019-10-21)
    The functioning of the heart, which main role is pumping blood to the rest of the body, is the result of a complex combination of multi-scale physical processes from the molecular to the tissue level. The predominance of ...
  • How do coil configuration and packing density influence intra-aneurysmal hemodynamics?
    Morales, Hernán G.; Kim, Minsuok; Vivas, EE; Villa-Uriol, Maria-Cruz; Larrabide, Ignacio, 1978-; Sola, T; Guimaraens, Leopoldo; Frangi Caregnato, Alejandro (American Society of Neuroradiology, 2011)
    Endovascular coiling is a well-established therapy for treating intracranial aneurysms. Nonetheless, postoperative hemodynamic changes induced by this therapy remain not fully understood. The purpose of this work is to ...
  • Meshless electrophysiological modeling of cardiac resynchronization therapy: benchmark analysis with finite-element methods in experimental data
    Albors Lucas, Carlos; Lluch Alvarez, Èric; Gomez, Juan Francisco; Cedilnik, Nicolas; Mountris, Konstantinos A.; Mansi, Tommaso; Khamzin, Svyatoslav; Dokuchaev, Arsenii; Solovyova, Olga; Pueyo, Esther; Sermesant, Maxime; Sebastian, Rafael; Morales, Hernán G.; Camara, Oscar (MDPI, 2022)
    Computational models of cardiac electrophysiology are promising tools for reducing the rates of non-response patients suitable for cardiac resynchronization therapy (CRT) by optimizing electrode placement. The majority of ...
  • Personalized computational framework to study arrhythmia mechanisms on top of ECGI-detected sub-strate
    Cluitmans, Matthijs J.M.; Lluch Alvarez, Èric; Morales, Hernán G.; Heijman, Jordi; Vaulders, Paul (Institute of Electrical and Electronics Engineers (IEEE), 2018)
    Electrocardiographic Imaging (ECGI) can unmask electrical abnormalities that were difficult to detect using the standard 12-lead ECG. However, it is still challenging to interpret the potential arrhythmogenic consequence ...
  • Sensitivity analysis of geometrical parameters to study haemodynamics and thrombus formation in the left atrial appendage
    García-Isla, Guadalupe; Olivares Miyares, Andy Luis; Silva, Etelvino; Nuñez-Garcia, Marta; Butakoff, Constantine; Sanchez-Quintana, Damian; Morales, Hernán G.; Freixa, Xavier; Noailly, Jérôme; De Potter, Tom; Camara, Oscar (Wiley, 2018)
    The left atrial appendage (LAA) is a complex and heterogeneous protruding structure of the left atrium (LA). In atrial fibrillation patients, it is the location where 90% of the thrombi are formed. However, the role of the ...
  • Smoothed particle hydrodynamics for electrophysiological modeling: an alternative to finite element methods
    Lluch Alvarez, Èric; Doste Beltrán, Rubén; Giffard-Roisin, Sophie; This, Alexandre; Sermesant, Maxime; Camara, Oscar; Craene, Mathieu de; Morales, Hernán G. (Springer, 2017)
    Finite element methods (FEM) are generally used in cardiac 3D-electromechanical modeling. For FEM modeling, a step of a suitable mesh construction is required, which is non-trivial and time-consuming for complex geometries. ...
  • Toward integrated management of cerebral aneurysms
    Villa-Uriol, Maria-Cruz; Larrabide, Ignacio, 1978-; Pozo Soler, José Ma. (José María); Kim, Minsuok; Camara, Oscar; Craene, Mathieu de; Zhang, Chong; Geers, Arjan; Morales, Hernán G.; Bogunovic, Hrvoje; Cardenes, Rubén; Frangi Caregnato, Alejandro (Royal Society, 2010)
    In the last few years, some of the visionary concepts behind the virtual physiological human began to be demonstrated on various clinical domains, showing great promise for improving healthcare management. In the current ...