Browsing by Author "Montserrat Pulido, Núria"

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  • Developing new strategies to understand human kidney development and target human disease
    Prado Peralta, Patricia Katherine, 1992- (2021-04-30)
    In recent years considerable progress has been made in the development of approaches for human pluripotent stem cells (hPSCs) differentiation. An important step in this direction has been the derivation of hPSCs derived ...
  • Direct reprogramming of human fibroblasts into insulin-producing cells using transcription factors
    Fontcuberta-PiSunyer, Marta; García-Alamán, Ainhoa; Prades, Èlia; Téllez, Noèlia; Alves-Figueiredo, Hugo; Ramos-Rodríguez, Mireia; Enrich, Carlos; Fernandez-Ruiz, Rebeca; Cervantes, Sara; Clua, Laura; Ramón-Azcón, Javier; Broca, Christophe; Wojtusciszyn, Anne; Montserrat Pulido, Núria; Pasquali, Lorenzo; Novials, Anna; Servitja, Joan-Marc; Vidal Alaball, Josep; Gomis, Ramon; Gasa, Rosa (Nature Research, 2023)
    Direct lineage reprogramming of one somatic cell into another without transitioning through a progenitor stage has emerged as a strategy to generate clinically relevant cell types. One cell type of interest is the pancreatic ...
  • Engineering human pluripotent stem cells to understand kidney development and disease
    Selfa Aspiroz, Idoia Lucía, 1992- (2022-02-09)
    During the last years, the development of procedures to direct the differentiation of human pluripotent stem cells (hPSCs) towards different renal cell types has resulted in the establishment of approaches focused on the ...
  • Generation and validation of a CRISPR platform for rapid and inducible genome editing in human pluripotent stem cells and kidney organoids
    Marco Giménez, Andrés, 1993- (2022-03-16)
    Our current knowledge about the function of human genes is mostly based on data from genetic studies using animal models. However, divergence among species may hamper the understanding of genetic mechanisms underlying human ...
  • Generation of feeder-free pig induced pluripotent stem cells without Pou5f1
    Montserrat Pulido, Núria; Oñate Monje, Lorena de, 1985-; Garreta Bahima, Elena; González, Federico; Adamo, Antonio; Eguizábal, Cristina; Häfner, Sophia; Vassena, Rita; Izpisúa Belmonte, J. C. (Cognizant Communication Corporation, 2012)
    The pig represents an ideal large-animal model, intermediate between rodents and humans, for the preclinical assessment of emerging cell therapies. As no validated pig embryonic stem (pES) cell lines have been derived so ...
  • Generation of induced pluripotent stem cells from human cord blood cells with only two factors:OCT4 and SOX2
    Giorgetti, Alessandra; Montserrat Pulido, Núria; Rodríguez Pizà, Ignasi; Azqueta, Carmen; Veiga, Anna; Izpisúa Belmonte, J. C. (Nature Publishing Group, 2010)
    Induced pluripotent stem cells (iPSC ) provide an invaluable resource for regenerative medicine as they allow the generation/nof patient-specific progenitors with potential value for cell therapy. However, in many instances, ...
  • Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector
    Rodríguez Pizà, Ignasi; Barragan, Montserrat; González, Federico; Izpisúa Belmonte, J. C.; Batlle Morera, Laura; Vassena, Rita; Montserrat Pulido, Núria; Tiscornia, Gustavo (National Academy of Sciences, 2009)
    Induced pluripotent stem (iPS) cells have generated keen interest/ndue to their potential use in regenerative medicine. They have/nbeen obtained from various cell types of both mice and humans by/nexogenous delivery of ...
  • Müller glia fused with adult stem cells undergo neural differentiation in human retinal models
    Bonilla-Pons, Sergi A.; Nakagawa, Shoma; Garreta Bahima, Elena; Fernández-Blanco, Álvaro; Pesaresi, Martina, 1991-; D'Antin, Justin Christopher; Sebastian-Perez, Ruben; Greco, Daniela; Domínguez-Sala, Eduardo; Gómez-Riera, Raúl; Barraquer Compte, Rafael Ignacio; Dierssen, Mara; Montserrat Pulido, Núria; Cosma, Maria Pia (Elsevier, 2022)
    Background: Visual impairments are a critical medical hurdle to be addressed in modern society. Müller glia (MG) have regenerative potential in the retina in lower vertebrates, but not in mammals. However, in mice, in vivo ...
  • Research on cardiac differentiation from human pluripotent stem cells: how to get beating cells in a dish
    Oñate Monje, Lorena de, 1985- (Universitat Pompeu Fabra, 2016-12-14)
    Probably, the gain in organ complexity and cell function has led to a decrease in healing capacities in the adult mammalian heart. In an effort to generate new venues for the generation of functional cardiac cells, in the ...