Browsing by Author "Moiseeva, Victoria, 1992-"

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  • 3-Deazaadenosine alleviates senescence to promote cellular fitness and cell therapy efficiency in mice
    Guerrero, Ana; Innes, Andrew J.; Roux, Pierre-François; Buisman, Sonja C.; Jung, Johannes; Ortet Cortada, Laura; Moiseeva, Victoria, 1992-; Wagner, Verena; Robinson, Lucas; Ausema, Albertina; Potapova, Anna; Perdiguero, Eusebio, 1968-; Weersing, Ellen; Aarts, Marieke; Martin, Nadine; Wuestefeld, Torsten; Muñoz Cánoves, Pura, 1962-; Haan, Gerald de; Bischof, Oliver; Gil, Jesús (Nature Research, 2022)
    Cellular senescence is a stable type of cell cycle arrest triggered by different stresses. As such, senescence drives age-related diseases and curbs cellular replicative potential. Here, we show that 3-deazaadenosine (3DA), ...
  • Protocol for RNA-seq library preparation starting from a rare muscle stem cell population or a limited number of mouse embryonic stem cells
    Dell'Orso, Stefania; Juan, Aster H.; Moiseeva, Victoria, 1992-; García Prat, Laura; Muñoz Cánoves, Pura, 1962-; Sartorelli, Vittorio (Elsevier, 2021)
    It remains challenging to generate reproducible, high-quality cDNA libraries from RNA derived from rare cell populations. Here, we describe a protocol for high-throughput RNA-seq library preparation, including isolation ...
  • Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration
    Moiseeva, Victoria, 1992-; Cisneros, Andrés; Sica, Valentina; Deryagin, Oleg; Andrés, Eva; Segalés Dalmau, Jessica; Ortet Cortada, Laura; Lukesova, Vera; Serrano Sánchez, Antonio L.; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962- (Nature Research, 2023)
    Tissue regeneration requires coordination between resident stem cells and local niche cells1,2. Here we identify that senescent cells are integral components of the skeletal muscle regenerative niche that repress regeneration ...

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