Browsing by Author "Meyerhans, Andreas"

Sort by: Order: Results:

  • Tretyakova, Rufina M.; Meyerhans, Andreas; Bocharov, Gennady A. (De Gruyter, 2015)
    In our study we developed a computational algorithm for finding optimal dosages of antiretroviral drug administration for the stabilization of HIV load at low levels. The novelty is that the pharmacokinetics and pharmacodynamics ...
  • Banks, H.T.; Sutton, Karyn L.; Thompson, W. Clayton; Bocharov, Gennady A.; Doumic, Marie; Schenkel, Tim; Argilaguet Marqués, Jordi, 1977-; Giest, Sandra; Peligero Cruz, Cristina, 1986-; Meyerhans, Andreas (Elsevier, 2011)
    CFSE analysis of a proliferating cell population is a popular tool for the study of cell division and divisionlinked changes in cell behavior. Recently Banks et al. (2011), Luzyanina et al. (2009), Luzyanina et al. (2007), ...
  • Banks, H.T.; Kapraun, Dustin F.; Thompson, W. Clayton; Peligero Cruz, Cristina, 1986-; Argilaguet, Jordi; Meyerhans, Andreas (Taylor & Francis (Routledge), 2013)
    A recently developed class of models incorporating the cyton model of population generation structure into a conservation-based model of intracellular label dynamics is reviewed. Statistical aspects of the data collection ...
  • Latorre, Irene; Leidinger, Petra; Backes, Christina; Domínguez, Jose; de Souza-Galvao, Malú; Maldonado, Jose; Prat, Cristina; Ruiz, Juan Jesús; Sánchez Martínez, Francisca; Casas, Irma; Keller, Andreas; Briesen, Hagen von; Knobel Freud, Hernando; Meese, Eckart; Meyerhans, Andreas (European Respiratory Society, 2015)
    Background: Deregulation of microRNAs (miRNAs)has been associated with various human pathologies including bacterial infections.Aim: To investigate the role of miRNAs as blood biomarkers for the diagnosis of active pulmonary ...
  • Banks, H.T.; Kapraun, Dustin F.; Link, Kathryn; Thompson, W. Clayton; Peligero Cruz, Cristina, 1986-; Argilaguet, Jordi; Meyerhans, Andreas (De Gruyter, 2015)
    In this article we assess variability in cell proliferation dynamics observed for CD4+ and CD8+ T cells collected from two healthy donors. We review a recently developed class of models that incorporates the so-called ...
  • Meyerhans, Andreas; Schultz, Anke; Koch, Stefanie; Fuss, Martina; Mazzotta, Angela S.; Sarzotti-Kelsoe, Marcella; Ozaki, Daniel A.; Montefiori, David C; Briesen, Hagen von; Zimmermann, Heiko (Public Library of Science (PLoS), 2012)
    Background: Infections with HIV still represent a major human health problem worldwide and a vaccine is the only long-term option to fight efficiently against this virus. Standardized assessments of HIV-specific immune ...
  • Olvera, Alex; Martínez, Javier P.; Casadellà, Maria; Llano, Anuska; Rosás, Míriam; Mothe, Beatriz; Ruiz Riol, Marta; Arsequell, Gemma; Valencia, Gregorio; Noguera Julián, Marc; Paredes, Roger; Meyerhans, Andreas; Brander, Christian (Frontiers, 2018)
    Glycosylation of host and viral proteins is an important posttranslational modification needed to ensure correct function of glycoproteins. For this reason, we asked whether inhibition of O-glycosylation during human ...
  • Fleta Soriano, Eric, 1983- (Universitat Pompeu Fabra, 2015-12-18)
    Hundreds of host factors related to viral infections like HIV, hepatitis C virus, dengue virus or West Nile virus have been identified. As many of these host factors are shared by different viruses, chemical blockade of ...
  • Latorre, Irene; Esteve-Solé, Ana; Redondo Pachón, María Dolores; Giest, Sandra; Argilaguet, Jordi; Álvarez, Sara; Peligero Cruz, Cristina, 1986-; Forstmann, Isabelle; Crespo Barrio, Marta; Pascual Santos, Julio; Meyerhans, Andreas (Elsevier, 2016)
    BACKGROUND: Regulatory B (Breg) and T (Treg) cells represent a biomarker for tolerance in transplant patients. Despite the importance of Treg and Breg in transplantation and the suggested crosstalk between both suppressive ...
  • Meyerhans, Andreas (BioMed Central, 2010)
    Background: Investigations on pulmonary macrophages (MΦ) mostly focus on alveolar MΦ (AM) as a well-defined cell population. Characteristics of MΦ in the interstitium, referred to as lung interstitial MΦ (IM), are rather ...
  • Banks, H.T.; Sutton, Karyn L.; Thompson, W. Clayton; Bocharov, Gennady A.; Roose, Dirk; Schenkel, Tim; Meyerhans, Andreas (Springer, 2011)
    Advances in fluorescent labeling of cells as measured by flow cytometry have allowed for quantitative studies of proliferating populations of cells. The investigations (Luzyanina et al. in J. Math. Biol. 54:57-89, 2007; ...
  • Banks, H.T.; Kapraun, Dustin F.; Peligero Cruz, Cristina, 1986-; Argilaguet, Jordi; Meyerhans, Andreas (Academic Publications, 2015)
    We carry out computational inverse problem investigations to determine the importance of allowing for unequal label allocation to daughter cells during mitosis. Parameter estimations are performed using previously developed ...
  • Martinez, Javier P.; Bocharov, Gennady A.; Ignatovich, Anna; Reiter, Jochen; Dittmar, Matthias T; Wain-Hobson, Simon; Meyerhans, Andreas (Public Library of Science (PLoS), 2011)
    Fitness interactions between mutations, referred to as epistasis, can strongly impact evolution. For RNA viruses and retroviruses with their high mutation rates, epistasis may be particularly important to overcome fitness ...
  • Kobayashi-Ishihara, Mie; Terahara, Kazutaka; Martínez Vesga, Javier Pablo; Yamagishi, Makoto; Iwabuchi, Ryutaro; Brander, Christian; Ato, Manabu; Watanabe, Toshiki; Meyerhans, Andreas; Tsunetsugu-Yokota, Yasuko (Frontiers, 2018)
    Latently infected T lymphocytes are an important barrier toward eliminating a persistent HIV infection. Here we describe an HIV-based recombinant fluorescent-lentivirus referred to as “rfl-HIV” that enables to analyze sense ...
  • Tsunetsugu-Yokota, Yasuko; Kobayashi-Ishihara, Mie; Wada, Yamato; Terahara, Kazutaka; Takeyama, Haruko; Kawana-Tachikawa, Ai; Tokunaga, Kenzo; Yamagishi, Makoto; Martínez Vesga, Javier Pablo; Meyerhans, Andreas (Frontiers, 2016)
    Homeostatic proliferation (HSP) is a major mechanism by which long-lived naïve and memory CD4+ T cells are maintained in vivo and suggested to contribute to the persistence of the latent HIV-1 reservoir. However, while ...
  • Bouchnita, Anass; Bocharov, Gennady A.; Meyerhans, Andreas; Volpert, Vitaly (BioMed Central, 2017)
    BACKGROUND: Moving from the molecular and cellular level to a multi-scale systems understanding of immune responses requires the development of novel approaches to integrate knowledge and data from different biological ...
  • Martinez, Javier P.; Hinkelmann, Bettina; Fleta Soriano, Eric, 1983-; Steinmetz, Heinrich; Jansen, Rolf; Díez Antón, Juana, 1962-; Frank, Ronald; Sasse, Florenz; Meyerhans, Andreas (BioMed Central, 2013)
    Drug-resistance and therapy failure due to drug-drug interactions are the main challenges in current treatment against Human Immunodeficiency Virus (HIV) infection. As such, there is a continuous need for the development ...
  • Herrmann, Madeleine; Ruprecht, Klemens; Sauter, Marlies; Martinez, Javier P.; van Heteren, Pearl; Glas, Michael; Best, Barbara; Meyerhans, Andreas; Roemer, Klaus; Mueller-Lantzsch, Nikolaus (Elsevier, 2010)
    Retrovirus replication critically depends on a dynamic interplay between retroviral and host proteins. We report on the binding of the surface subunit (glycoprotein 120 (gp120)) of the human immunodeficiency virus type 1 ...
  • Riera Domínguez, María Graciela, 1987- (Universitat Pompeu Fabra, 2018-12-10)
    The host immune response against infection requires the coordinated action of many diverse cell subsets that dynamically adapt to a pathogen threat. Due to the complexity of such a response, most immunological studies have ...
  • Carreras Sureda, Amado, 1986-; Rubio Moscardó, Fanny; Olvera, Alex; Argilaguet, Jordi; Kiefer, Kerstin, 1986-; Mothe, Beatriz; Meyerhans, Andreas; Brander, Christian; Vicente García, Rubén, 1978- (Public Library of Science (PLoS), 2016)
    Single nucleotide polymorphisms (SNPs) located in the chromosome region 17q12-q21 are risk factors for asthma. Particularly, there are cis-regulatory haplotypes within this region that regulate differentially the expression ...