Browsing by Author "Merkenschlager, Matthias"

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  • Robles-Rebollo, Irene; Cuartero, Sergi; Canellas-Socias, Adria; Wells, Sarah; Karimi, Mohammad M.; Mereu, Elisabetta; Chivu, Alexandra G.; Heyn, Holger; Whilding, Chad; Dormann, Dirk; Marguerat, Samuel; Rioja, Inmaculada; Prinjha, Rab K.; Stumpf, Michael P.H.; Fisher, Amanda G.; Merkenschlager, Matthias (Nature Research, 2022)
    Innate immune responses rely on inducible gene expression programmes which, in contrast to steady-state transcription, are highly dependent on cohesin. Here we address transcriptional parameters underlying this cohesin-dependence ...
  • Karimi, Mohammad M.; Ruiz Gil, Sara; Rodríguez Esteban, Gustavo; Merkenschlager, Matthias (Nature Research, 2021)
    CD4 and CD8 mark helper and cytotoxic T cell lineages, respectively, and serve as coreceptors for MHC-restricted TCR recognition. How coreceptor expression is matched with TCR specificity is central to understanding CD4/CD8 ...
  • Cuartero, Sergi; Innes, Andrew J.; Merkenschlager, Matthias (Frontiers, 2019)
    Classical driver mutations in acute myeloid leukemia (AML) typically affect regulators of cell proliferation, differentiation, and survival. The selective advantage of increased proliferation, improved survival, and reduced ...

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