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Browsing by Author "Mendoza, Manuel (Mendoza Palomares)"

Browsing by Author "Mendoza, Manuel (Mendoza Palomares)"

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  • Ivanova, Tsvetomira Georgieva, 1978-; Maier, Michael, 1983-; Missarova, Alsu, 1990-; Ziegler-Birling, Céline; Dam, Monica; Gomar-Alba, Mercè; Carey, Lucas, 1980-; Mendoza, Manuel (Mendoza Palomares) (Nature Research, 2020)
    To faithfully transmit genetic information, cells must replicate their entire genome before division. This is thought to be ensured by the temporal separation of replication and chromosome segregation. Here we show that ...
  • Battola, Andrea (Universitat Pompeu Fabra, 2018-12-20)
    Problemes en la replicació de l’ADN, condensació o de-catenació generen ponts anafàsics al punt de divisió, que en molts casos provoquen inestabilitat genòmica. La cèl·lula respon a aquest problema activant la via del ...
  • Masgrau Fortuny, Aina, 1986-; Battola, Andrea, 1987-; Sanmartín Olmo, Trinidad; Pryszcz, Leszek Piotr, 1985-; Gabaldón Estevan, Juan Antonio, 1973-; Mendoza, Manuel (Mendoza Palomares) (American Society for Cell Biology, 2017)
    Boi1 and Boi2 (Boi1/2) are budding yeast plasma membrane proteins that function in polarized growth, and in cytokinesis inhibition in response to chromosome bridges via the NoCut abscission checkpoint. How Boi1/2 act in ...
  • Maya Miles, Douglas; Peñate, Xenia; Sanmartín Olmo, Trinidad; Jourquin, Frederic; Muñoz Centeno, Maria Cruz; Mendoza, Manuel (Mendoza Palomares); Simon, Marie-Noelle; Chávez, Sebastián; Geli, Vincent (eLife, 2018)
    Whole-genome duplications (WGDs) have played a central role in the evolution of genomes and constitute an important source of genome instability in cancer. Here, we show in Saccharomyces cerevisiae that abnormal accumulations ...
  • Di Stefano, Marco; Di Giovanni, Francesca, 1985-; Pozharskaia, Vasilia; Gomar-Alba, Mercè; Baù, Davide; Carey, Lucas, 1980-; Marti-Renom, Marc A.; Mendoza, Manuel (Mendoza Palomares) (Genetics Society of America, 2020)
    The three-dimensional (3D) organization of chromosomes can influence transcription. However, the frequency and magnitude of these effects remain debated. To determine how changes in chromosome positioning affect transcription ...
  • Amaral, Nuno (Universitat Pompeu Fabra, 2017-06-02)
    La coordinació de la citocinesis amb la segregació cromosòmica és essencial per mantenir l’estabilitat cromosòmica durant la proliferació cel•lular. Tant en llevat com en cèl•lules animals, els ponts de cromatina en anafase ...
  • Amaral, Nuno, 1984-; Vendrell Arasa, Alexandre; Funaya, Charlotta; Idrissi, Fatima-Zahra; Maier, Michael, 1983-; Kumar, Arun; Neurohr, Gabriel Erich; Colomina, Neus; Torres Rosell, Jordi; Geli, María-Isabel; Mendoza, Manuel (Mendoza Palomares) (Nature Publishing Group, 2016)
    Anaphase chromatin bridges can lead to chromosome breakage if not properly resolved before completion of cytokinesis. The NoCut checkpoint, which depends on Aurora B at the spindle midzone, delays abscission in response ...

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