Browsing by Author "Mayneris Perxachs, Jordi"

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  • Adipose tissue coregulates cognitive function
    Oliveras Cañellas, Núria; Castells-Nobau, Anna; Vega-Correa, Lisset de la; Latorre-Luque, Jessica; Motger-Albertí, Anna; Arnoriaga Rodríguez, María; Garre-Olmo, Josep; Zapata-Tona, Cristina; Coll Martínez, Clàudia; Ramió-Torrentà, Lluís; Moreno-Navarrete, José Maria; Puig, Josep; Villarroya, Francesc; Ramos, Rafel; Casadó-Anguera, Verònica; Martín García, Elena, 1975-; Maldonado, Rafael, 1961-; Mayneris Perxachs, Jordi; Fernández Real, Jose M. (American Association for the Advancement of Science (AAAS), 2023)
    Obesity is associated with cognitive decline. Recent observations in mice propose an adipose tissue (AT)-brain axis. We identified 188 genes from RNA sequencing of AT in three cohorts that were associated with performance ...
  • Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans
    Mayneris Perxachs, Jordi; Castells-Nobau, Anna; Arnoriaga Rodríguez, María; Garre-Olmo, Josep; Puig, Josep; Ramos, Rafel; Martínez Hernández, Francisco; Burokas, Aurelijus, 1982-; Coll, Clàudia; Moreno-Navarrete, José Maria; Zapata-Tona, Cristina; Pedraza, Salvador; Pérez Brocal, Vicente; Ramió-Torrentà, Lluís; Ricart, Wifredo; Moya, Andrés; Martínez García, Manuel; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (Elsevier, 2022)
    Growing evidence implicates the gut microbiome in cognition. Viruses, the most abundant life entities on the planet, are a commonly overlooked component of the gut virome, dominated by the Caudovirales and Microviridae ...
  • Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile
    Arnoriaga Rodríguez, María; Mayneris Perxachs, Jordi; Burokas, Aurelijus, 1982-; Pérez Brocal, Vicente; Moya, Andrés; Portero Otín, Manuel; Ricart, Wifredo; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (BioMed Central, 2020)
    Background: The chaperone ClpB, a bacterial protein, is a conformational antigen-mimetic of α-melanocyte-stimulating hormone (α-MSH) implicated in body weight regulation in mice. We here investigated the potential associations ...
  • Gut microbiota signatures of vulnerability to food addiction in mice and humans
    Samulenaite, Solveiga; García Blanco, Alejandra; Mayneris Perxachs, Jordi; Domingo Rodriguez, Laura, 1992-; Cabana-Domínguez, Judit; Fernàndez-Castillo, Noèlia; Gago-García, Edurne; Pineda-Cirera, Laura; Burokas, Aurelijus, 1982-; Espinosa-Carrasco, José; Arboleya, Silvia; Latorre, Jessica; Stanton, Catherine; Hosomi, Koji; Kunisawa, Jun; Cormand, Bru; Fernández Real, Jose M.; Maldonado, Rafael, 1961-; Martín García, Elena, 1975- (BMJ Publishing Group, 2024)
    Objective: Food addiction is a multifactorial disorder characterised by a loss of control over food intake that may promote obesity and alter gut microbiota composition. We have investigated the potential involvement of ...
  • Gut microbiota steroid sexual dimorphism and its impact on gonadal steroids: influences of obesity and menopausal status
    Mayneris Perxachs, Jordi; Arnoriaga Rodríguez, María; Luque-Córdoba, Diego; Priego-Capote, Feliciano; Pérez Brocal, Vicente; Moya, Andrés; Burokas, Aurelijus, 1982-; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (BioMed Central, 2020)
    Background: Gonadal steroid hormones have been suggested as the underlying mechanism responsible for the sexual dimorphism observed in metabolic diseases. Animal studies have also evidenced a causal role of the gut microbiome ...
  • Impact of phenol-enriched olive oils on serum metabonome and its relationship with cardiometabolic parameters. a randomized, double-blind, cross-over, controlled trial
    Farràs Mañé, Marta; Swann, Jonathan Richard; Rowland, Ian; Rubió, Laura; Subirana Cachinero, Isaac; Catalán, Úrsula; Motilva, Maria-José; Solà, Rosa; Covas Planells, Maria Isabel; Blanco-Vaca, Francisco; Fitó Colomer, Montserrat; Mayneris Perxachs, Jordi (MDPI, 2022)
    Phenol-rich foods consumption such as virgin olive oil (VOO) has been shown to have beneficial effects on cardiovascular diseases. The broader biochemical impact of VOO and phenol-enriched OOs remains, however, unclear. A ...
  • Microbiota alterations in proline metabolism impact depression
    Mayneris Perxachs, Jordi; Martin, Miquel; Burokas, Aurelijus, 1982-; Escrichs, Anira; Deco, Gustavo; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (Elsevier, 2022)
    The microbiota-gut-brain axis has emerged as a novel target in depression, a disorder with low treatment efficacy. However, the field is dominated by underpowered studies focusing on major depression not addressing microbiome ...
  • miRNA signatures associated with vulnerability to food addiction in mice and humans
    García Blanco, Alejandra; Domingo Rodriguez, Laura, 1992-; Cabana-Domínguez, Judit; Fernández-Castillo, Noèlia; Pineda-Cirera, Laura; Mayneris Perxachs, Jordi; Burokas, Aurelijus, 1982-; Espinosa-Carrasco, José; Arboleya, Silvia; Latorre, Jessica; Stanton, Catherine; Cormand, Bru; Fernández Real, Jose M.; Martín-García, Elena; Maldonado, Rafael, 1961- (American Society for Clinical Investigation, 2022)
    Food addiction is characterized by a loss of behavioral control over food intake and is associated with obesity and other eating disorders. The mechanisms underlying this behavioral disorder are largely unknown. We aimed ...
  • Presence of blastocystis in gut microbiota is associated with cognitive traits and decreased executive function
    Mayneris Perxachs, Jordi; Arnoriaga Rodríguez, María; Garre-Olmo, Josep; Puig, Josep; Ramos, Rafel; Trelis, Maria; Burokas, Aurelijus; Coll, Clàudia; Zapata-Tona, Cristina; Pedraza, Salvador; Pérez Brocal, Vicente; Ramió-Torrentà, Lluís; Ricart, Wifredo; Moya, Andrés; Jové, Mariona; Sol, Joaquim; Portero Otín, Manuel; Pamplona, Reinald; Maldonado, Rafael, 1961-; Fernández Real, Jose M. (Nature Research, 2022)
    Growing evidence implicates the gut microbiome in cognition. Blastocystis is a common gut single-cell eukaryote parasite frequently detected in humans but its potential involvement in human pathophysiology has been poorly ...

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