Browsing by Author "Martinelli, Paola"

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  • Zhong, Yi; Wang, Zheng; Fu, Baojin; Pan, Fan; Yachida, Shinichi; Dhara, Mousumi; Albesiano, Emilia; Li, Li; Naito, Yoshiki; Vilardell, Felip; Cummings, Christopher; Martinelli, Paola; Li, Ang; Yonescu, Raluca; Ma, Qingyong; Griffin, Constance A; Real, Francisco X.; Iacobuzio Donahue, Christine A (Public Library of Science (PLoS), 2011)
    Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease characterized by late diagnosis and treatment resistance. Recurrent genetic alterations in defined genes in association with perturbations of developmental ...
  • Martinelli, Paola; Carrillo, Enrique; Cox, Trevor; Sainz, Bruno Jr; Dusetti, Nelson; Greenhalf, William; Rinaldi, Lorenzo, 1986-; Costello, Eithne; Ghaneh, Paula; Malats i Riera, Núria; Büchler, Markus; Pajic, Marina; Biankin, Andrew V.; Iovanna, Juan; Neoptolemos, John; Real, Francisco X. (BMJ Publishing Group, 2017)
    BACKGROUND AND AIMS: The role of GATA factors in cancer has gained increasing attention recently, but the function of GATA6 in pancreatic ductal adenocarcinoma (PDAC) is controversial. GATA6 is amplified in a subset of ...
  • Hruschka, Natascha; Andreu Martínez, David; Real, Francisco X.; Martinelli, Paola (Nature Research, 2020)
    As the catalog of oncogenic driver mutations is expanding, it becomes clear that alterations in a given gene might have different functions and should not be lumped into one class. The transcription factor GATA3 is a ...