Browsing by Author "Martínez-Rodriguez, José E."

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  • Adaptive features of natural killer cells in multiple sclerosis
    Moreira Villanueva, Antía; Alari-Pahissa, Elisenda; Munteis Olivas, Elvira; Vera, Andrea; Zabalza, Ana; Llop, Mireia; Villarrubia, Noelia; Costa García, Marcel, 1989-; Álvarez-Lafuente, Roberto; Villar, Luisa Maria; López-Botet, Miguel; Martínez-Rodriguez, José E. (Frontiers, 2019)
    Human cytomegalovirus (HCMV) has been recently related with a lower susceptibility to multiple sclerosis (MS). HCMV promotes an adaptive development of NK cells bearing the CD94/NKG2C receptor with a characteristic phenotypic ...
  • Development of the adaptive NK cell response to human cytomegalovirus in the context ofaging
    López-Botet, Miguel; Muntasell i Castellví, Aura, 1972-; Martínez-Rodriguez, José E.; López-Montañés, María; Costa-García, Marcel; Pupuleku, Aldi, 1985- (Elsevier, 2016)
    Human cytomegalovirus (HCMV) establishes a highly prevalent life-long latent infection. Though generally subclinical, HCMV infection may have severe consequences during fetal development and in immunocompromised individuals. ...
  • Dynamics and predictors of cognitive impairment along the disease course in multiple sclerosis
    López-Soley, Elisabet; Martínez-Heras, Eloy; Andorrà, Magí; Solanes, Aleix; Radua, Joaquim; Montejo, Carmen; Alba-Arbalat, Salut; Solà-Valls, Núria; Pulido Valdeolivas, Irene; Sepúlveda, Maria; Romero-Pinel, Lucía; Munteis Olivas, Elvira; Martínez-Rodriguez, José E.; Blanco, Yolanda; Martínez Lapiscina, Elena H.; Villoslada, Pablo; Saiz, Albert; Solana, Elisabeth; Llufriu, Sara (MDPI, 2021)
    Background: the evolution and predictors of cognitive impairment (CI) in multiple sclerosis (MS) are poorly understood. We aimed to define the temporal dynamics of cognition throughout the disease course and identify ...
  • Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis.
    Ortiz, Miguel A.; Núñez, Concepción; Ordóñez, David; Álvarez Cermeño, Jose Carlos; Martínez-Rodriguez, José E.; Sánchez, Antonio J.; Arroyo, Rafael; Izquierdo, Guillermo; Malhotra, Sunny, 1984-; Montalbán Gairín, Xavier; García Merino, Antonio; Munteis Olivas, Elvira; Alcina, Antonio; Comabella López, Manuel; Matesanz, Fuencisla; Villar, Luisa Maria; Urcelay, Elena (Public Library of Science, 2015)
    BACKGROUND: Multiple sclerosis (MS) is a neurodegenerative, autoimmune disease of the central nervous system. Genome-wide association studies (GWAS) have identified over hundred polymorphisms with modest individual effects ...
  • Low cytomegalovirus seroprevalence in early multiple sclerosis: a case for the 'hygiene hypothesis'?
    Alari-Pahissa, Elisenda; Moreira Villanueva, Antía; Zabalza, Ana; Alvarez-Lafuente, Roberto; Munteis Olivas, Elvira; Vera, Andrea; Arroyo, Rafael; Álvarez Cermeño, Jose Carlos; Villar, Luisa Maria; López-Botet, Miguel; Martínez-Rodriguez, José E. (Wiley, 2018)
    BACKGROUND AND PURPOSE: Cytomegalovirus (CMV) infection has recently been associated with a lower multiple sclerosis (MS) susceptibility, although it remains controversial whether it has a protective role or is merely an ...