Browsing by Author "Martí, Eulàlia"

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  • A high-throughput screening identifies microRNA inhibitors that influence neuronal maintenance and/or response to oxidative stress
    Pallarès Albanell, Joan, 1988-; Zomeño-Abellán, M. Teresa; Escaramís, Geòrgia; Pantano Rubiño, Lorena, 1982-; Soriano, Aroa; Segura, Miguel F.; Martí, Eulàlia (Elsevier, 2019)
    Small non-coding RNAs (sncRNAs), including microRNAs (miRNAs) are important post-transcriptional gene expression regulators relevant in physiological and pathological processes. Here, we combined a high-throughput functional ...
  • A highly expressed miR-101 isomiR is a functional silencing small RNA
    Llorens, Franc; Bañez Coronel, Mónica; Pantano Rubiño, Lorena, 1982-; del Río, José Antonio; Ferrer, Isidre; Estivill, Xavier, 1955-; Martí, Eulàlia (BioMed Central, 2013)
    Background: MicroRNAs (miRNAs) are short non-coding regulatory RNAs that control gene expression usually producing translational repression and gene silencing. High-throughput sequencing technologies have revealed heterogeneity ...
  • A common 56-kilobase deletion in a primate-specific segmental duplication creates a novel butyrophilin-like protein
    Aigner, Johanna, 1981-; Villatoro, Sergi; Rabionet, Raquel; Roquer, Jaume; Jiménez Conde, Jordi; Martí, Eulàlia; Estivill, Xavier, 1955- (BioMed Central, 2013)
    Background: The Butyrophilin-like (BTNL) proteins are likely to play an important role in inflammation and immune response. Like the B7 protein family, many human and murine BTNL members have been shown to control T ...
  • Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor
    Llorens, Franc; Hummel, Manuela; Pantano Rubiño, Lorena, 1982-; Pastor, Xavier; Vivancos Prellezo, Ana; Castillo Andreo, Esther; Mattlin, Heidi; Ferrer Admetlla, Anna; Ingham, Matthew; Noguera, Marc; Kofler, Robert; Dohm, Juliane C.; Pluvinet, Raquel; Bayés, Mònica; Himmelbauer, Heinz; del Río, José Antonio; Martí, Eulàlia; Sumoy Van Dyck, Lauro (BioMed Central, 2013)
    Background: Epidermal Growth Factor (EGF) plays an important function in the regulation of cell growth, proliferation, and differentiation by binding to its receptor (EGFR) and providing cancer cells with increased survival ...
  • Small non-coding RNAs add complexity to the RNA pathogenic mechanisms in trinucleotide repeat expansion diseases
    Martí, Eulàlia; Estivill, Xavier, 1955- (Frontiers, 2013)
    Trinucleotide-repeat expansion diseases (TREDs) are a group of inherited human genetic disorders normally involving late-onset neurological/neurodegenerative affectation. Trinucleotide-repeat expansions occur in coding and ...
  • Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
    Rué, Laura; Bañez Coronel, Mónica; Creus-Muncunill, Jordi; Giralt, Albert; Alcalá-Vida, Rafael; Mentxaka, Gartze; Kagerbauer, Birgit; Zomeño-Abellán, M. Teresa; Aranda, Zeus; Venturi, Veronica; Pérez-Navarro, Esther; Estivill, Xavier, 1955-; Martí, Eulàlia (American Society for Clinical Investigation, 2016)
    Huntington's disease (HD) is a polyglutamine disorder caused by a CAG expansion in the Huntingtin (HTT) gene exon 1. This expansion encodes a mutant protein whose abnormal function is traditionally associated with HD ...

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