Browsing by Author "Marrugat de la Iglesia, Jaume"

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  • NCD Risk Factor Collaboration (NCD-RisC); Álvarez Pedrerol, Mar; Marrugat de la Iglesia, Jaume; Porta Serra, Miquel; Sunyer Deu, Jordi (eLife, 2016)
    Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height ...
  • Dégano, Irene R.; Subirana Cachinero, Isaac; Torre, Marina; Grau Magaña, Maria; Vila, Joan; Fusco, Danilo; Kirchberger, Inge; Ferrières, Jean; Malmivaara, Antti; Azevedo, Ana; Meisinger, Christa; Bongard, Vanina; Farmakis, Dimitrios; Davoli, Marina; Häkkinen, Unto; Araújo, Carla; Lekakis, John; Elosua Llanos, Roberto; Marrugat de la Iglesia, Jaume (Elsevier, 2015)
    BACKGROUND: Hospital performance models in acute myocardial infarction (AMI) are useful to assess patient management. While models are available for individual countries, mainly US, cross-European performance models are ...
  • Sayols, Sergi; Fernández Sanlés, Alba; Prats Uribe, Albert; Subirana Cachinero, Isaac; Plusquin, Michelle; Künzli, Nino; Marrugat de la Iglesia, Jaume; Basagaña Flores, Xavier; Elosua Llanos, Roberto (Elsevier, 2019)
    INTRODUCTION: Limited evidence suggests that epigenetic mechanisms may partially mediate the adverse effects of air pollution on health. Our aims were to identify new genomic loci showing differential DNA methylation ...
  • Rivera, Marcela, 1982-; Basagaña Flores, Xavier; Aguilera Jiménez, Inmaculada, 1977-; Foraster Pulido, Maria, 1984-; Agis, David; Groot, Eric de; Pérez Grau, Laura; Mendez, Michelle A.; Bouso, Laura; Targa, Jaume; Ramos, Rafel; Sala, Joan; Marrugat de la Iglesia, Jaume; Elosua Llanos, Roberto; Künzli, Nino (National Institute of Environmental Health Sciences (NIEHS), 2013)
    BACKGROUND: Epidemiological evidence of the effects of long-term exposure to air pollution on the chronic processes of atherogenesis is limited. OBJECTIVE: We investigated the association of long-term exposure to traffic-related ...
  • Dégano, Irene R.; Camps-Vilaró, Anna; Subirana Cachinero, Isaac; García-Mateo, Nadia; Cidad, Pilar; Muñoz Aguayo, Daniel; Puigdecanet Riubugent, Eulàlia; Nonell Mazelón, Lara; Vila, Joan; Crepaldi, Felipe M.; Gonzalo-Calvo, David de; Llorente-Cortés, Vicenta; Pérez García, María Teresa; Elosua Llanos, Roberto; Fitó Colomer, Montserrat; Marrugat de la Iglesia, Jaume (MDPI, 2020)
    Risk prediction tools cannot identify most individuals at high coronary artery disease (CAD) risk. Oxidized low-density lipoproteins (oxLDLs) and microRNAs are actively involved in atherosclerosis. Our aim was to examine ...
  • Foraster Pulido, Maria, 1984-; Basagaña Flores, Xavier; Aguilera Jiménez, Inmaculada, 1977-; Rivera, Marcela, 1982-; Agis, David; Bouso, Laura; Deltell, Alexandre; Marrugat de la Iglesia, Jaume; Ramos, Rafel; Sunyer Deu, Jordi; Vila, Joan; Elosua Llanos, Roberto; Künzli, Nino (National Institute of Environmental Health Sciences (NIEHS), 2014)
    Background: Long-term exposure to traffic-related air pollution may increase blood pressure (BP) and induce hypertension. However, evidence supporting these associations is limited, and they may be confounded by exposure ...
  • Elosua Llanos, Roberto; Lluís Ganella, Carla, 1984-; Subirana Cachinero, Isaac; Havulinna, Aki; Läll, Kristi; Lucas, Gavin, 1977-; Sayols, Sergi; Pietilä, Arto; Alver, Maris; Cabrera de León, Antonio; Sentí Clapés, Mariano; Siscovick, David; Mellander, Olle; Fischer, Krista; Salomaa, Veikko; Marrugat de la Iglesia, Jaume (Lippincott Williams & Wilkins, 2016)
    BACKGROUND: Cardiovascular risk factors tend to aggregate. The biological and predictive value of this aggregation is questioned and genetics could shed light on this debate. Our aims were to reappraise the impact of risk ...
  • Fa-Binefa, Manel; Clarà Velasco, Alberto; Pérez-Fernández, Silvia; Grau Magaña, Maria; Dégano, Irene R.; Martí-Lluch, Ruth; Ramos, Rafel; Marrugat de la Iglesia, Jaume; Elosua Llanos, Roberto (Elsevier, 2019)
    Early smoking onset age (SOA) is a public health concern with scant empirical evidence of its role in health outcomes. The study had two aims: i) to assess whether an early SOA was associated with the risk of fatal and ...
  • Garcia Gil, Maria; Comas Cufí, Marc; Ramos, Rafel; Martí, Ruth; Alves-Cabratosa, Lia; Parramon, Dídac; Prieto-Alhambra, Daniel; Baena Díez, Jose M.; Salvador-González, Betlem; Elosua Llanos, Roberto; Dégano, Irene R.; Marrugat de la Iglesia, Jaume; Grau Magaña, Maria (SAGE Publications, 2019)
    Background: Cardiovascular guidelines do not give firm recommendations on statin therapy in patients with gout because evidence is lacking. Aim: To analyze the effectiveness of statin therapy in primary prevention of ...
  • Cuadrado Godia, Elisa; Regueiro, Ander; Núñez, Julio; Díaz-Ricard, Maribel; Novella, Susana; Oliveras, Anna; Valverde, M. A. (Miguel Ángel), 1963-; Marrugat de la Iglesia, Jaume; Ois Santiago, Angel Javier; Giralt-Steinhauer, Eva; Sanchís, Juan; Escolar, Ginès; Hermenegildo, Carlos; Heras, Magda; Roquer, Jaume (Public Library of Science, 2015)
    INTRODUCTION: The aim of this study was to determine prognostic factors for the risk of new vascular events during the first 6 months after acute myocardial infarction (AMI) or atherothrombotic stroke (AS). We were interested ...
  • Camps-Vilaró, Anna; Delgado-Jiménez, Juan F.; Farré López, Núria; Tizón-Marcos, Helena; Álvarez-García, Jesus; Cinca, Juan; Dégano, Irene R.; Marrugat de la Iglesia, Jaume (MDPI, 2020)
    Heart failure (HF) is one of the main causes of morbidity, mortality, and high healthcare costs. Dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, reduced cardiovascular mortality and hospitalization for ...
  • Zamora, Alberto; Masana, Luís; Comas Cufí, Marc; Vila, Alex; Plana, Nuria; Garcıa-Gil, Maria; Alves-Cabratosa, Lia; Marrugat de la Iglesia, Jaume; Roman Degano, Irene; Ramos, Rafel; XULA and ISV-Girona groups (Elsevier, 2017)
    BACKGROUND: Familial hypercholesterolemia (FH), the most frequent hereditary cause of premature coronary heart disease (CHD), is underdiagnosed and insufficiently treated. OBJECTIVES: The objectives of the study were to ...
  • Fernández-Fernández, José Manuel, 1967-; Tomás Mestres, Marta; Vázquez Gómez, Esther; Orio, Patricio; Latorre, Ramón; Sentí Clapés, Mariano; Marrugat de la Iglesia, Jaume; Valverde, M. A. (Miguel Ángel), 1963- (American Society for Clinical Investigation, 2004)
    Hypertension is the most prevalent risk factor for cardiovascular diseases, present in almost 30% of adults. A key element in the control of vascular tone is the large-conductance, Ca(2+)-dependent K(+) (BK) channel. The ...
  • Sayols, Sergi; Subirana Cachinero, Isaac; Lluís Ganella, Carla, 1984-; Civeira, Fernando; Roquer, Jaume; Do, AN; Absher, Devin; Cenarro, A.; Muñoz, Dani; Soriano Tarraga, Carolina; Jiménez Conde, Jordi; Ordovás, José M.; Sentí Clapés, Mariano; Aslibekyan, Stella W.; Marrugat de la Iglesia, Jaume; Arnett, Donna K.; Elosua Llanos, Roberto (Oxford University Press, 2016)
    Lipid traits (total, low-densityand high-density lipoproteincholesterol, and triglycerides) are risk factors for cardiovascular disease. DNA methylation is an inherited but also modifiable epigenetic mark ...
  • Sayols, Sergi; Lluís Ganella, Carla, 1984-; Subirana Cachinero, Isaac; Salas, Lucas A.; Vilahur Chiaraviglio, Nadia, 1982-; Corella, Dolores; Muñoz, Dani; Segura, Antoni, 1952-; Jiménez Conde, Jordi; Moran, Sebastian; Soriano Tarraga, Carolina; Roquer, Jaume; Lopez-Farré, Antonio; Marrugat de la Iglesia, Jaume; Fitó Colomer, Montserrat; Elosua Llanos, Roberto (Taylor & Francis, 2015)
    Smoking increases the risk of many diseases and could act through changes in DNA methylation patterns. The aims of this study were to determine the association between smoking and DNA methylation throughout the genome at ...
  • Masana, Luís; Zamora, Alberto; Plana, Nuria; Comas Cufí, Marc; Garcıa-Gil, Maria; Martí, Ruth; Ponjoan, Anna; Alves-Cabratosa, Lia; Elosua Llanos, Roberto; Marrugat de la Iglesia, Jaume; Dégano, Irene R.; Ramos, Rafel (MDPI, 2019)
    In the statin era, the incidence of atherosclerotic cardiovascular diseases (ASCVD) in patients with familial hypercholesterolemia (FH) has not been updated. We aimed to determine the incidence of ASCVD in patients with ...
  • Barroso, María; Goday Arno, Alberto; Marrugat de la Iglesia, Jaume; FRESCO Investigators (Elsevier, 2018)
    The effect of above-normal body mass index (BMI) on health outcomes is controversial because it is difficult to distinguish from the effect due to BMI-associated cardiovascular risk factors. The objective was to analyze ...
  • Wain, Louise V.; Marrugat de la Iglesia, Jaume; Elosua Llanos, Roberto; Ehret, Georg B. (American Hearth Association, 2017)
    Elevated blood pressure is a major risk factor for cardiovascular disease and has a substantial genetic contribution. Genetic variation influencing blood pressure has the potential to identify new pharmacological targets ...
  • Dégano, Irene R.; Subirana Cachinero, Isaac; Fusco, Danilo; Tavazzi, Luigi; Kirchberger, Inge; Farmakis, Dimitrios; Ferrières, Jean; Azevedo, Ana; Torre, Marina; Garel, Pascal; Brosa, Max; Davoli, Marina; Meisinger, Christa; Bongard, Vanina; Araújo, Carla; Lekakis, John; Francès, Albert; Castell, Conxa; Elosua Llanos, Roberto; Marrugat de la Iglesia, Jaume; EUROTRACS investigators (Elsevier, 2017)
    BACKGROUND: Percutaneous coronary intervention (PCI) reduces mortality in most myocardial infarction (MI) patients but the effect on elderly patients with comorbidities is unclear. Our aim was to analyse the effect of PCI ...
  • Subirana Cachinero, Isaac; Fitó Colomer, Montserrat; Díaz Gil, Oscar; Vila, Joan; Francés Comalat, Albert; Delpon, Eva; Sanchís, Juan; Elosua Llanos, Roberto; Muñoz-Aguayo, D.; Dégano, Irene R.; Marrugat de la Iglesia, Jaume (Nature Research, 2019)
    The effect of circulating biomarkers in predicting coronary artery disease (CAD) is not fully elucidated. This study aimed to determine the relationship with CAD and the predictive capacity of nine biomarkers of inflammation ...