Browsing by Author "Manichanh, Chaysavanh"

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  • Guigó Serra, Roderic; Manichanh, Chaysavanh; Chapple, Charles E.; Frangeul, Lionel; Gloux, Karine; Dore, Joel (Oxford University Press, 2008)
    The construction of metagenomic libraries has permitted the study of microorganisms resistant to isolation and the analysis of 16S rDNA sequences has been used for over two decades to examine bacterial biodiversity. Here, ...
  • Martinez, Xavier; Pozuelo, Marta; Pascal, Victoria; Campos, David; Gut, Ivo Glynne; Gut, Marta; Azpiroz, Fernando; Guarner, Francisco; Manichanh, Chaysavanh (Nature Publishing Group, 2016)
    To date, meta-omic approaches use high-throughput sequencing technologies, which produce a huge amount of data, thus challenging modern computers. Here we present MetaTrans, an efficient open-source pipeline to analyze the ...
  • Manichanh, Chaysavanh; Reeder, Jens; Gibert, Prudence; Varela, Encarna; Llopis, Marta; Antolin, Maria; Guigó Serra, Roderic; Knight, Rob; Guarner, Francisco (Cold Spring Harbor Laboratory Press, 2010)
    The intestinal microbiota consists of over 1000 species, which play key roles in gut physiology and homeostasis. Imbalances in the composition of this bacterial community can lead to transient intestinal dysfunctions and ...
  • Nikolaou, Christoforos; Bermúdez, Ignacio; Manichanh, Chaysavanh; García Martínez, José; Guigó Serra, Roderic; Pérez Ortín, José E.; Roca, Joaquim (Oxford University Press, 2013)
    Eukaryotic topoisomerase II (topo II) is the essential decatenase of newly replicated chromosomes and the main relaxase of nucleosomal DNA. Apart from these general tasks, topo II participates in more specialized functions. ...

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