Browsing by Author "Manichanh, Chaysavanh"

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  • A comparison of random sequence reads versus 16S rDNA sequences for estimating the biodiversity of a metagenomic library
    Guigó Serra, Roderic; Manichanh, Chaysavanh; Chapple, Charles E.; Frangeul, Lionel; Gloux, Karine; Dore, Joel (Oxford University Press, 2008)
    The construction of metagenomic libraries has permitted the study of microorganisms resistant to isolation and the analysis of 16S rDNA sequences has been used for over two decades to examine bacterial biodiversity. Here, ...
  • MetaTrans: an open-source pipeline for metatranscriptomics
    Martinez, Xavier; Pozuelo, Marta; Pascal, Victoria; Campos, David; Gut, Ivo Glynne; Gut, Marta; Azpiroz, Fernando; Guarner, Francisco; Manichanh, Chaysavanh (Nature Publishing Group, 2016)
    To date, meta-omic approaches use high-throughput sequencing technologies, which produce a huge amount of data, thus challenging modern computers. Here we present MetaTrans, an efficient open-source pipeline to analyze the ...
  • Reshaping the gut microbiome with bacterial transplantation and antibiotic intake
    Manichanh, Chaysavanh; Reeder, Jens; Gibert, Prudence; Varela, Encarna; Llopis, Marta; Antolin, Maria; Guigó Serra, Roderic; Knight, Rob; Guarner, Francisco (Cold Spring Harbor Laboratory Press, 2010)
    The intestinal microbiota consists of over 1000 species, which play key roles in gut physiology and homeostasis. Imbalances in the composition of this bacterial community can lead to transient intestinal dysfunctions and ...
  • Topoisomerase II regulates yeast genes with singular chromatin architectures
    Nikolaou, Christoforos; Bermúdez, Ignacio; Manichanh, Chaysavanh; García Martínez, José; Guigó Serra, Roderic; Pérez Ortín, José E.; Roca, Joaquim (Oxford University Press, 2013)
    Eukaryotic topoisomerase II (topo II) is the essential decatenase of newly replicated chromosomes and the main relaxase of nucleosomal DNA. Apart from these general tasks, topo II participates in more specialized functions. ...

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